Search Results - "Cope, L."

Intragenomic variation in non-adaptive nucleotide biases causes underestimation of selection on synonymous codon usage by Cope, Alexander L, Shah, Premal

“…Patterns of non-uniform usage of synonymous codons vary across genes in an organism and between species across all domains of life. This codon usage bias (CUB)…”
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Individual-based modeling explains the contrasted seasonality in size, growth, and reproduction of the sympatric Arctic (Thysanoessa raschii) and Nordic krill (Meganyctiphanes norvegica) in the St. Lawrence Estuary, eastern Canada by Benkort, D., Plourde, S., Winkler, G., Cabrol, J., Ollier, A., Cope, L.-E., Maps, F.

“…The Nordic krill Meganyctiphanes norvegica and Arctic krill Thysanoessa raschii both dominate the krill community within the Estuary and Gulf of St. Lawrence…”
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Quantifying shifts in natural selection on codon usage between protein regions: a population genetics approach by Cope, Alexander L, Gilchrist, Michael A

“…Codon usage bias (CUB), the non-uniform usage of synonymous codons, occurs across all domains of life. Adaptive CUB is hypothesized to result from various…”
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Randomised clinical trial: gut microbiome biomarkers are associated with clinical response to a low FODMAP diet in children with the irritable bowel syndrome by Chumpitazi, B. P., Cope, J. L., Hollister, E. B., Tsai, C. M., McMeans, A. R., Luna, R. A., Versalovic, J., Shulman, R. J.

“…Summary Background A low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet can ameliorate symptoms in adult irritable…”
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Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity by Ottolini, Matteo, Hong, Kwangseok, Cope, Eric L., Daneva, Zdravka, DeLalio, Leon J., Sokolowski, Jennifer D., Marziano, Corina, Nguyen, Nhiem Y., Altschmied, Joachim, Haendeler, Judith, Johnstone, Scott R., Kalani, Mohammad Y., Park, Min S., Patel, Rakesh P., Liedtke, Wolfgang, Isakson, Brant E., Sonkusare, Swapnil K.

“…BACKGROUND:Impaired endothelium-dependent vasodilation is a hallmark of obesity-induced hypertension. The recognition that Ca signaling in endothelial cells…”
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Anaesthetic depth and complications after major surgery: an international, randomised controlled trial by Campbell, Douglas, Frampton, Christopher, Myles, Paul S, Corcoran, Tomás B, Byrne, Kelly, Chu, Mandy H M, Leslie, Kate, Wallace, S, Farrington, C, Ditoro, A, Reynolds, J, Rowley, J, Wong, S, Pushpanathan, M, Cavill, D, Lucas, J, Allen, M, Jowett, C, Kearney, A, Bennett, M, Drummond, K, Osborn, S, Reynolds, H, Terblanche, N, Challis, M, Button, K, Cotter, R, Stewart, M, Middleton, D, Jeong, S, Connell, K, Kramer, K, Henderson, G, Buller, Y, Scott, D, Said, S, Baby, D, Jeffreys, A, Paranthoiene, R, Peng, P, Zhou, X, Jin, X, An, L, Cui, W, Jia, B, Fang, J, Koo, E, Lo, E, Fung, B, Lam, L, Pang, E, Yau, K, Lam, C, Buggy, D, Keane, H, Cervantes, A, Kennedy, R, McKellow, M, France, D, Moniwa, A, Chaddock, M, Gray, L, Vinish, S, Williams, E, Zhou, C, Goodman, L, Mans, G, Franks, R, van Kampen, A, Pai, A, Sevillano, A, Yeung, J, Melody, T, Atterbury, K, Dukes, S, Milan, Z, Kunst, G, MacNab, W, Moulding, R, Rees, B, Faulkner, B, Blackburn, J, Nair, A, Bell, G, Garratt, T, Pollard, M, Brown, G, Martin, T, Jhanji, S, Turan, M, Morris, A, Saxon, J, Ruiz, J, Dangler, L, Ifeanyi-Pillette, I, Erfe, R, Perez, A, Yang, G, Cooke, F, Friedlander, R

“…An association between increasing anaesthetic depth and decreased postoperative survival has been shown in observational studies; however, evidence from…”
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The timing of heat waves has multiyear effects on milkweed and its insect community by Cope, Olivia L., Zehr, Luke N., Agrawal, Anurag A., Wetzel, William C.

“…Extreme heat events are becoming more frequent and intense as climate variability increases, and these events inherently vary in their timing. We predicted…”
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Impact of Oral Fidaxomicin Administration on the Intestinal Microbiota and Susceptibility to Clostridium difficile Colonization in Mice by Ajami, N J, Cope, J L, Wong, M C, Petrosino, J F, Chesnel, L

“…infection (CDI), a common cause of hospital-acquired infections, typically occurs after disruption of the normal gut microbiome by broad-spectrum antibiotics…”
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Gene expression of functionally-related genes coevolves across fungal species: detecting coevolution of gene expression using phylogenetic comparative methods by Cope, Alexander L, O'Meara, Brian C, Gilchrist, Michael A

“…Researchers often measure changes in gene expression across conditions to better understand the shared functional roles and regulatory mechanisms of different…”
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Morphology and Classification of Right Ventricular Bands in the Domestic Dog (Canis familiaris) by Cope, L. A.

“…Summary Ventricular bands, also designated as ‘false tendons’, are described as single or multiple strands that cross the ventricles and have no connection to…”
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The Global Evolution of Foreign Relations Law by Cope, Kevin L., Verdier, Pierre-Hugues, Versteeg, Mila

“…The constitutional rules that govern how states engage with international law have profound implications for foreign affairs, yet we lack comprehensive data on…”
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Re-purposing 16S rRNA gene sequence data from within case paired tumor biopsy and tumor-adjacent biopsy or fecal samples to identify microbial markers for colorectal cancer by Shah, Manasi S, DeSantis, Todd, Yamal, Jose-Miguel, Weir, Tiffany, Ryan, Elizabeth P, Cope, Julia L, Hollister, Emily B

“…Microbes colonizing colorectal cancer (CRC) tumors have the potential to affect disease, and vice-versa. The manner in which they differ from microbes in…”
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Morphological Variations in the Canine (Canis familiaris) Right Ventricle Trabecula Septomarginalis Dextra and a Proposed Classification Scheme by Cope, L. A.

“…Summary The trabecula septomarginalis dextra is a structure routinely mentioned in veterinary anatomy. While there are several studies on the morphology of…”
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Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation by Cope, Claire L, Gilley, Rebecca, Balmanno, Kathryn, Sale, Matthew J, Howarth, Karen D, Hampson, Mark, Smith, Paul D, Guichard, Sylvie M, Cook, Simon J

“…The mechanistic target of rapamycin (mTOR) protein kinase coordinates responses to nutrients and growth factors and is an anti-cancer drug target. To…”
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A mechanical task for measuring sign- and goal-tracking in humans: A proof-of-concept study by Cope, L.M., Gheidi, A., Martz, M.E., Duval, E.R., Khalil, H., Allerton, T., Morrow, J.D.

“…Cue-based associative learning (i.e., Pavlovian conditioning) is a foundational component of behavior in almost all forms of animal life and may provide…”
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Nitric Oxide–Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries by Marziano, Corina, Hong, Kwangseok, Cope, Eric L., Kotlikoff, Michael I., Isakson, Brant E., Sonkusare, Swapnil K.

“…Background Recent studies demonstrate that spatially restricted, local Ca2+ signals are key regulators of endothelium‐dependent vasodilation in systemic…”
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The landscape of transcriptional and translational changes over 22 years of bacterial adaptation by Favate, John S, Liang, Shun, Cope, Alexander L, Yadavalli, Srujana S, Shah, Premal

“…Organisms can adapt to an environment by taking multiple mutational paths. This redundancy at the genetic level, where many mutations have similar phenotypic…”
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Atypical Chordae Tendineae of the Canine (Canis familiaris) Right Atrioventricular Valve by Cope, L. A.

“…Summary The canine right atrioventricular valve cusps are anchored to papillary muscles by chordae tendineae. During ventricular systole, these tendineae keep…”
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CONGRESS'S INTERNATIONAL LEGAL DISCOURSE by Cope, Kevin L.

“…Despite Congress's important role in enforcing U.S. international law obligations, the relevant existing literature largely ignores the branch. This omission…”
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Patients' reasons for consulting a GP when experiencing a dental problem: a qualitative study by Cope, Anwen L, Wood, Fiona, Francis, Nick A, Chestnutt, Ivor G

“…There are approximately 380 000 dental consultations in UK general practice every year. To explore the reasons why patients may consult a GP rather than a…”
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