Search Results - "Cope, Heidi L"
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Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling
Published in The American journal of pathology (2016)“…Obesity is an independent risk factor for the development of liver fibrosis/cirrhosis and hepatocellular carcinoma (HCC). Tenascin-C (TnC), an extracellular…”
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Cyclooxygenase inhibition does not blunt thermal hyperemia in skeletal muscle of humans
Published in Journal of applied physiology (1985) (2024)“…Acute heat exposure increases skeletal muscle blood flow in humans. However, the mechanisms mediating this hyperemic response remain unknown. The…”
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Effect of acute heat exposure on the pressor response to a voluntary hypoxic apnea
Published in Journal of applied physiology (1985) (01-09-2023)“…The pressor response induced by a voluntary hypoxic apnea is mediated largely by increased sympathetic outflow. The neural control of blood pressure is altered…”
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Effect of Acute Heat Exposure on the Pressor Response to a Voluntary Hypoxic Apnea: A Cross‐Tolerance Study
Published in The FASEB journal (01-05-2022)“…The pressor response induced by a voluntary hypoxic apnea is exaggerated in individuals with obstructive sleep apnea and is strongly correlated to sympathetic…”
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A systematic framework for selecting gene-condition pairs for inclusion in newborn sequencing panels: Early Check implementation
Published in Genetics in medicine (01-12-2024)“…Research is underway worldwide to investigate the feasibility, acceptability, and utility of sequencing-based newborn screening. Different methods have been…”
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Enzyme replacement therapy with alglucosidase alfa in Pompe disease: Clinical experience with rate escalation
Published in Molecular genetics and metabolism (01-02-2018)“…Patients with Pompe disease have realized significant medical benefits due to enzyme replacement therapy (ERT) infusions with alglucosidase alfa. However,…”
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Genetic Association Analyses of Nitric Oxide Synthase Genes and Neural Tube Defects Vary by Phenotype
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01-10-2013)“…Neural tube defects (NTDs) are caused by improper neural tube closure during the early stages of embryonic development. NTDs are hypothesized to have a complex…”
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