Search Results - "Coordes, Britta"
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Ctk1 function is necessary for full translation initiation activity in Saccharomyces cerevisiae
Published in Eukaryotic cell (01-01-2015)“…Translation is a fundamental and highly regulated cellular process. Previously, we reported that the kinase and transcription elongation factor Ctk1 increases…”
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Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling
Published in Nature structural & molecular biology (01-07-2012)“…The Mre11–Rad50–Nbs1 (MRN) complex plays a central role in DNA damage signaling. The crystal structures of the Schizosaccharomyces pombe Mre11 catalytic domain…”
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Cyclin-dependent Kinase 9 Links RNA Polymerase II Transcription to Processing of Ribosomal RNA
Published in The Journal of biological chemistry (19-07-2013)“…Ribosome biogenesis is a process required for cellular growth and proliferation. Processing of ribosomal RNA (rRNA) is highly sensitive to flavopiridol, a…”
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Structural biology of the Mre11:Nbs1 complex structure yields insights into ataxia–telangiectasia–like disease mutations and DNA damage signaling
Published in Nature structural & molecular biology (17-06-2012)“…The Mre11–Rad50–Nbs1 (MRN) complex tethers, processes and signals DNA double strand breaks, promoting genomic stability. To understand the functional…”
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