Search Results - "Cooper, S T"

Characterisation of hypertensive heart disease: pathological insights from a sudden cardiac death cohort to inform clinical practice by Westaby, J. D., Miles, C., Chis Ster, I., Cooper, S. T. E., Antonios, T. F., Meijles, D., Behr, E. R., Sheppard, M. N.

“…Hypertensive heart disease refers to changes in the myocardium that result from hypertension. The relationship between hypertensive heart disease and sudden…”
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Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair by Redpath, G M I, Woolger, N, Piper, A K, Lemckert, F A, Lek, A, Greer, P A, North, K N, Cooper, S T

“…Dysferlin and calpain are important mediators of the emergency response to repair plasma membrane injury. Our previous research revealed that membrane injury…”
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Heterozygous CAPN3 missense variants causing autosomal‐dominant calpainopathy in seven unrelated families by González‐Mera, L., Ravenscroft, G., Cabrera‐Serrano, M., Ermolova, N., Domínguez‐González, C., Arteche‐López, A., Soltanzadeh, P., Evesson, F., Navas, C., Mavillard, F., Clayton, J., Rodrigo, P., Servián‐Morilla, E., Cooper, S. T, Waddell, L., Reardon, K., Corbett, A., Hernandez‐Laín, A., Sanchez, A., Esteban Perez, J., Paradas‐Lopez, C., Rivas‐Infante, E., Spencer, M., Laing, N., Olivé, M.

“…Aims Recessive variants in CAPN3 gene are the cause of the commonest form of autosomal recessive limb girdle muscle dystrophy. However, two distinct in‐frame…”
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Mechanisms underlying intranuclear rod formation by Domazetovska, Ana, Ilkovski, Biljana, Cooper, Sandra T., Ghoddusi, Majid, Hardeman, Edna C., Minamide, Laurie S., Gunning, Peter W., Bamburg, James R., North, Kathryn N.

“…Specific mutations within the α-skeletal actin gene (ACTA1) result in intranuclear rod myopathy (IRM), characterized by rod-like aggregates containing actin…”
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Mutagenesis of recombinant protein C inhibitor reactive site residues alters target proteinase specificity by PHILLIPS, J. E, COOPER, S. T, POTTER, E. E, CHURCH, F. C

“…Protein C inhibitor (PCI) is a heparin-binding plasma serine proteinase inhibitor (serpin) which is thought to be a physiological regulator of activated…”
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Identification of domains influencing assembly and ion channel properties in α7 nicotinic receptor and 5‐HT3 receptor subunit chimaeras by Gee, V J, Kracun, S, Cooper, S T, Gibb, A J, Millar, N S

“…Background and purpose: Nicotinic acetylcholine receptors (nAChRs) and 5‐hydroxytryptamine type 3 receptors (5‐HT3Rs) are members of the superfamily of…”
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Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin by FORTENBERRY, Y. M., WHINNA, H. C., COOPER, S. T., MYLES, T., LEUNG, L. L. K., CHURCH, F. C.

“…Background: Protein C inhibitor (PCI) and antithrombin (AT) are serine protease inhibitors (serpins) that inhibit a wide array of blood coagulation serine…”
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Nemaline Myopathy Caused by Mutations in the Muscle α-Skeletal-Actin Gene by Ilkovski, Biljana, Cooper, Sandra T., Nowak, Kristen, Ryan, Monique M., Yang, Nan, Schnell, Christina, Durling, Hayley J., Roddick, Laurence G., Wilkinson, Ian, Kornberg, Andrew J., Collins, Kevin J., Wallace, Geoff, Gunning, Peter, Hardeman, Edna C., Laing, Nigel G., North, Kathryn N.

“…Nemaline myopathy (NM) is a clinically and genetically heterogeneous disorder characterized by muscle weakness and the presence of nemaline bodies (rods) in…”
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Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin Complex (∗) by Rezaie, Alireza R., Cooper, Scott T., Church, Frank C., Esmon, Charles T.

“…Protein C inhibitor (PCI), a plasma serine protease inhibitor, inhibits several proteases including the anticoagulant enzyme, activated protein C (APC), and…”
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Construction of Recombinant Adeno-Associated Virus Vector Containing the Rat Preproinsulin II Gene by Peng, Lan, Sidner, Richard A., Bochan, Markian R., Burton, Matthew M., Cooper, Scott T., Jindal, Rahul M.

“…We have investigated a possible delivery system for the rat preproinsulin II gene (rI2) utilizing a recombinant adeno-associated virus (rAAV) vector system,…”
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Pig apolipoprotein R: A new member of the short consensus repeat family of proteins by Cooper, Scott T, Attie, Alan D

“…Apolipoprotein R (apoR) is a 23-kDa protein found on very low-density lipoprotein (VLDL), on chylomicrons, and in the d > 1.21 g/mL fraction of pig plasma. The…”
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Distal regulatory elements control MRF4 gene expression in early and late myogenic cell populations by Pin, Christopher L., Ludolph, David C., Cooper, Scott T., Klocke, Barbara J., Merlie, John P., Konieczny, Stephen F.

“…MRF4 is a muscle‐specific transcription factor that belongs to a family of basic helix‐loop‐helix proteins known as the myogenic regulatory factors (MRFs). In…”
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Intermolecular Interactions between Protein C Inhibitor and Coagulation Proteases by Cooper, Scott T, Whinna, Herbert C, Jackson, Tracy P, Boyd, Jennifer M, Church, Frank C

“…Protein C inhibitor (PCI) inhibits multiple plasma serine proteases. To determine which residues contribute to its specificity of inhibition, 19 mutations in…”
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PCI: protein C inhibitor? by Cooper, S T, Church, F C

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C2C12 Co-culture on a fibroblast substratum enables sustained survival of contractile, highly differentiated myotubes with peripheral nuclei and adult fast myosin expression by Cooper, S.T., Maxwell, A.L., Kizana, E., Ghoddusi, M., Hardeman, E.C., Alexander, I.E., Allen, D.G., North, K.N.

“…We describe a simple culture method for obtaining highly differentiated clonal C2C12 myotubes using a feeder layer of confluent fibroblasts, and document the…”
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Identification of domains influencing assembly and ion channel properties in α 7 nicotinic receptor and 5‐HT 3 receptor subunit chimaeras by Gee, V J, Kracun, S, Cooper, S T, Gibb, A J, Millar, N S

“…Background and purpose: Nicotinic acetylcholine receptors (nAChRs) and 5‐hydroxytryptamine type 3 receptors (5‐HT 3 Rs) are members of the superfamily of…”
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Assessment of the interaction between urokinase and reactive site mutants of protein C inhibitor by Jackson, T P, Cooper, S T, Church, F C

“…Urokinase-type plasminogen activator (uPA) is a serine protease involved in pericellular proteolysis and tumor cell metastasis via plasmin-mediated degradation…”
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Host Cell‐Specific Folding and Assembly of the Neuronal Nicotinic Acetylcholine Receptor α7 Subunit by Cooper, Sandra T., Millar, Neil S.

“…: Expression of the cloned neuronal nicotinic acetylcholine receptor (nAChR) α7 subunit in several cultured mammalian cell lines has revealed that the folding,…”
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Spectinomycin for Asian-acquired gonorrhea by Hafermann, D R, Cooper, T S, Chesney, M A

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Identification of domains influencing assembly and ion channel properties in alpha 7 nicotinic receptor and 5-HT3 receptor subunit chimaeras by Gee, V J, Kracun, S, Cooper, S T, Gibb, A J, Millar, N S

“…Nicotinic acetylcholine receptors (nAChRs) and 5-hydroxytryptamine type 3 receptors (5-HT(3)Rs) are members of the superfamily of neurotransmitter-gated ion…”
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