Search Results - "Cooper, R. M."
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The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy
Published in Clinical pharmacology and therapeutics (01-07-2012)“…Cholesterol reduction from statin therapy has been one of the greatest public health successes in modern medicine. Simvastatin is among the most commonly used…”
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The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update
Published in Clinical pharmacology and therapeutics (01-10-2014)“…Simvastatin is among the most commonly used prescription medications for cholesterol reduction. A single coding single‐nucleotide polymorphism, rs4149056T>C,…”
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Measurement of forces applied during Macintosh direct laryngoscopy compared with GlideScope® videolaryngoscopy
Published in Anaesthesia (01-06-2012)“…Summary Laryngoscopy can induce stress responses that may be harmful in susceptible patients. We directly measured the force applied to the base of the tongue…”
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Alkaliphilic Bacillus species show potential application in concrete crack repair by virtue of rapid spore production and germination then extracellular calcite formation
Published in Journal of applied microbiology (01-05-2017)“…Aims Characterization of alkaliphilic Bacillus species for spore production and germination and calcite formation as a prelude to investigate their potential…”
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Preclinical activity of CPI-0610, a novel small-molecule bromodomain and extra-terminal protein inhibitor in the therapy of multiple myeloma
Published in Leukemia (01-08-2017)“…Inhibition of the bromodomain and extra-terminal (BET) proteins is a promising therapeutic strategy for various hematologic cancers. Previous studies suggest…”
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Impact of CYP2D6 Polymorphisms on Clinical Efficacy and Tolerability of Metoprolol Tartrate
Published in Clinical pharmacology and therapeutics (01-08-2014)“…Metoprolol is a selective β‐1 adrenergic receptor blocker that undergoes extensive metabolism by the polymorphic enzyme cytochrome P450 2D6 (CYP2D6). Our…”
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Ganoderma boninense basidiospores in oil palm plantations: evaluation of their possible role in stem rots of Elaeis guineensis
Published in Plant pathology (01-06-2012)“…Basidiospores are implicated in the distribution and genetic diversity of Ganoderma boninense, cause of basal stem rot (BSR) and upper stem rot (USR) of oil…”
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Basal stem rot of oil palm (Elaeis guineensis); mode of root infection and lower stem invasion by Ganoderma boninense
Published in Plant pathology (01-10-2009)“…Reproducible infection of intact roots of oil palm (Elaeis guineensis) with Ganoderma boninense, the cause of basal stem rot, showed penetration followed by…”
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Alemtuzumab in Previously Treated Chronic Lymphocytic Leukemia Patients Who Also Had Received Fludarabine
Published in Journal of clinical oncology (15-09-2002)“…This phase II pilot study determined the efficacy and safety of alemtuzumab (Campath-1H; Burroughs Wellcome, United Kingdom) in patients with chronic…”
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Depressive symptoms in early pregnancy disrupt attentional processing of infant emotion
Published in Psychological medicine (01-04-2010)“…Growing evidence suggests that perinatal depression is associated with disrupted mother-infant interactions and poor infant outcomes. Antenatal depression may…”
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Evaluation of Malaysian oil palm progenies for susceptibility, resistance or tolerance to Fusarium oxysporum f. sp. elaeidis and defence‐related gene expression in roots
Published in Plant pathology (01-06-2015)“…Vascular wilt of oil palm caused by Fusarium oxysporum f. sp. elaeidis (Foe) is a devastating disease in West and Central Africa. As the oil palm industry in…”
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Hydrochlorothiazide‐induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study
Published in Journal of internal medicine (01-11-2014)“…Objective Elevations in uric acid (UA) and the associated hyperuricaemia are commonly observed secondary to treatment with thiazide diuretics. We sought to…”
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Phase I Studies of Anti–Epidermal Growth Factor Receptor Chimeric Antibody C225 Alone and in Combination With Cisplatin
Published in Journal of clinical oncology (01-02-2000)“…The epidermal growth factor (EGF) receptor is frequently overexpressed in epithelial tumors. C225 is a human-to-murine chimeric monoclonal antibody that binds…”
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Effects of inoculum potential, shading and soil temperature on root infection of oil palm seedlings by the basal stem rot pathogen Ganoderma boninense
Published in Plant pathology (01-10-2007)“…Ganoderma boninense causes severe losses to oil palm in South East Asia. The disease typically manifests itself as basal stem rot, but there remains…”
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Forces generated by Macintosh and GlideScope® laryngoscopes in four airway‐training manikins
Published in Anaesthesia (01-05-2013)“…Summary We measured forces generated by Macintosh and GlideScope® laryngoscope blades during airway intubation by 16 participants in four manikins: Laerdal®…”
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Evolution of the Tyrone Ophiolite, Northern Ireland, during the Grampian-Taconic Orogeny; a correlative of the Annieopsquotch ophiolite belt of central Newfoundland?
Published in Journal of the Geological Society (01-11-2013)“…The Tyrone Plutonic Group of Northern Ireland represents the upper portions of a tectonically dissected suprasubduction-zone ophiolite accreted to the…”
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Age constraints and geochemistry of the Ordovician Tyrone igneous complex, Northern Ireland; implications for the Grampian Orogeny
Published in Journal of the Geological Society (01-07-2011)“…The Tyrone Igneous Complex is one of the largest areas of ophiolitic and arc-related rocks exposed along the northern margin of Iapetus within the British and…”
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Palaeogene Alpine tectonics and Icelandic plume-related magmatism and deformation in Northern Ireland
Published in Journal of the Geological Society (01-01-2012)“…The Cenozoic tectonic history of NW Europe is generally attributed to some combination of three principal controlling factors: North Atlantic opening, Alpine…”
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β-Adrenergic Receptor Gene Polymorphisms and β-Blocker Treatment Outcomes in Hypertension
Published in Clinical pharmacology and therapeutics (01-12-2008)“…Numerous studies have demonstrated that β1‐ and β2‐adrenergic receptor gene (ADRB1 and ADRB2) variants influence cardiovascular risk and β‐blocker responses in…”
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Difficult Airway Society guidelines for the management of tracheal extubation
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