Search Results - "Cooper, Peter C"

Recommendations for clinical laboratory testing for antithrombin deficiency; Communication from the SSC of the ISTH by Van Cott, Elizabeth M., Orlando, Christelle, Moore, Gary W., Cooper, Peter C., Meijer, Piet, Marlar, Richard

“…Hereditary deficiency of antithrombin, a natural anticoagulant, causes a thrombophilia with a high risk for venous thromboembolism. Guidance for laboratory…”
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Corn trypsin inhibitor in fluorogenic thrombin-generation measurements is only necessary at low tissue factor concentrations and influences the relationship between factor VIII coagulant activity and thrombogram parameters by van Veen, Joost J, Gatt, Alex, Cooper, Peter C, Kitchen, Steven, Bowyer, Annette E, Makris, Mike

“…The fluorogenic calibrated automated thrombin-generation assay is influenced by contact pathway activation in platelet-rich and platelet-poor plasma. This…”
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Recommendations for clinical laboratory testing for protein C deficiency, for the subcommittee on plasma coagulation inhibitors of the ISTH by Cooper, Peter C., Pavlova, Anna, Moore, Gary W., Hickey, Kieron P., Marlar, Richard A.

“…Inherited protein C (PC) deficiency increases risk of venous thromboembolism (VTE) by 5 to 10‐fold in thrombosis‐prone families; however, heterozygous PC…”
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Transient inherited antithrombin deficiency: a real phenomenon? by Daly, Martina E, Cooper, Peter C, Hickey, Kieron P, Jennings, Ian, Makris, Mike

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Calibrated automated thrombin generation and modified thromboelastometry in haemophilia A by van Veen, Joost J, Gatt, Alex, Bowyer, Annette E, Cooper, Peter C, Kitchen, Steve, Makris, Mike

“…Abstract Introduction Global coagulation tests may have a better relation with phenotype in haemophilia than traditional coagulation tests. These include the…”
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Quality in molecular biology testing for inherited thrombophilia disorders by Cooper, Peter C, Goodeve, Anne C, Beauchamp, Nicholas J

“…As the understanding of the genetic basis of the inherited thrombophilias has increased over recent years, their routine diagnostic genetic analysis has also…”
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Fatal spontaneous thrombosis of a cerebral arteriovenous malformation in a young patient with a rare heterozygous prothrombin gene mutation : Case report by TAHA, Mahmoud, PATEL, Umang, WHARTON, Stephen B, COOPER, Peter C, MAKRIS, Michael

“…The authors report a case of fatal stroke due to thrombosis of a cerebral arteriovenous malformation (AVM) in a young patient. The patient presented with a…”
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Detection of Factor V Leiden and prothrombin c.20210G>A allele by Roche Diagnostics LightCycler by Cooper, Peter C

“…Venous thrombosis affects one in one thousand people each year, and in many countries, it is a major cause of morbidity and death in hospitalised patients…”
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High prevalence of a mutation in the factor V gene within the U.K. population: relationship to activated protein C resistance and familial thrombosis by Beauchamp, N J, Daly, M E, Hampton, K K, Cooper, P C, Preston, F E, Peake, I R

“…Recent findings have indicated the importance of factor V (FV) in causing resistance to activated protein C (APC) in a high proportion of patients with venous…”
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Evaluation of the Roche LightCycler: a simple and rapid method for direct detection of factor V Leiden and prothrombin G20210A genotypes from blood samples without the need for DNA extraction by Cooper, Peter C, Cooper, Susan M, Smith, Julie M, Kitchen, Steven, Makris, Michael

“…The Roche LightCycler is a micro-volume thermocycler that combines extremely rapid polymerase chain reaction with fluorescence resonance energy transfer…”
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Genetic analysis, phenotypic diagnosis, and risk of venous thrombosis in families with inherited deficiencies of protein S by Makris, Michael, Leach, Michael, Beauchamp, Nick J., Daly, Martina E., Cooper, Peter C., Hampton, Kingsley K., Bayliss, Pauline, Peake, Ian R., Miller, George J., Preston, F. Eric

“…Protein S deficiency is a recognized risk factor for venous thrombosis. Of all the inherited thrombophilic conditions, it remains the most difficult to…”
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Molecular basis of protein S deficiency in three families also showing independent inheritance of factor V leiden by Beauchamp, N J, Daly, M E, Cooper, P C, Makris, M, Preston, F E, Peake, I R

“…The molecular basis of type I or III Protein S deficiency has been investigated in three kindred also showing independent inheritance of factor V (FV) Leiden…”
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Rapid two-stage PCR for detecting factor V G1691A mutation by Beauchamp, N J, Daly, M E, Cooper, P C, Preston, F E, Peake, I R

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