Search Results - "Cooper, Max D."

The evolution of adaptive immunity by Pancer, Zeev, Cooper, Max D

“…Approximately 500 mya two types of recombinatorial adaptive immune systems appeared in vertebrates. Jawed vertebrates generate a diverse repertoire of B and T…”
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Evolutionary implications of a third lymphocyte lineage in lampreys by Hirano, Masayuki, Guo, Peng, McCurley, Nathanael, Schorpp, Michael, Das, Sabyasachi, Boehm, Thomas, Cooper, Max D.

“…Cells expressing variable lymphocyte receptor C ( VLRC ) genes that encode VLRC receptors, which are used by jawless vertebrates to react with antigens, are…”
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Dual nature of the adaptive immune system in lampreys by Yu, Cuiling, Herrin, Brantley R, Sadlonova, Andrea, Li, Jianxu, Cooper, Max D, Hirano, Masayuki, Guo, Peng

“…Jawless vertebrates use variable lymphocyte receptors (VLR) comprised of leucine-rich-repeat (LRR) segments as counterparts of the immunoglobulin-based…”
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VLR-Based Adaptive Immunity by Boehm, Thomas, McCurley, Nathanael, Sutoh, Yoichi, Schorpp, Michael, Kasahara, Masanori, Cooper, Max D

“…Lampreys and hagfish are primitive jawless vertebrates capable of mounting specific immune responses. Lampreys possess different types of lymphocytes, akin to…”
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The evolution of adaptive immunity in vertebrates by Hirano, Masayuki, Das, Sabyasachi, Guo, Peng, Cooper, Max D

“…Approximately 500 million years ago, two types of recombinatorial adaptive immune systems (AISs) arose in vertebrates. The jawed vertebrates diversify their…”
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MicroRNA 125b inhibition of B cell differentiation in germinal centers by Gururajan, Murali, Haga, Christopher L., Das, Sabyasachi, Leu, Chuen-Miin, Hodson, Daniel, Josson, Sajni, Turner, Martin, Cooper, Max D.

“…MicroRNAs 125a and 125b are predicted to be able to bind to the B lymphocyte-induced maturation protein-1 (BLIMP-1) and IFN regulatory protein-4 (IRF-4)…”
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Alternative adaptive immunity in jawless vertebrates by Herrin, Brantley R, Cooper, Max D

“…Jawless vertebrates use variable lymphocyte receptors (VLRs) that are generated by RAG-independent combinatorial assembly of leucine-rich repeat cassettes for…”
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Evolution of two distinct variable lymphocyte receptors in lampreys: VLRD and VLRE by Das, Sabyasachi, Boehm, Thomas, Holland, Stephen J., Rast, Jonathan P., Fontenla-Iglesias, Francisco, Morimoto, Ryo, Valadez, J. Gerardo, Heimroth, Ryan D., Hirano, Masayuki, Cooper, Max D.

“…Jawless vertebrates possess an alternative adaptive immune system in which antigens are recognized by variable lymphocyte receptors (VLRs) generated by…”
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Antigen Recognition by Variable Lymphocyte Receptors by Han, Byung Woo, Herrin, Brantley R, Cooper, Max D, Wilson, Ian A

“…Variable lymphocyte receptors (VLRs) rather than antibodies play the primary role in recognition of antigens in the adaptive immune system of jawless…”
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Definition of a third VLR gene in hagfish by Li, Jianxu, Das, Sabyasachi, Herrin, Brantley R., Hirano, Masayuki, Cooper, Max D.

“…Jawless vertebrates (cyclostomes) have an alternative adaptive immune system in which lymphocytes somatically diversify their variable lymphocyte receptors…”
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The early history of B cells by Cooper, Max D.

“…As we celebrate 50 years since his seminal Nature paper describing separate lineages for B cells and T cells in the chicken, Max Cooper looks back at the early…”
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Organization of lamprey variable lymphocyte receptor C locus and repertoire development by Das, Sabyasachi, Hirano, Masayuki, Aghaallaei, Narges, Bajoghli, Baubak, Boehm, Thomas, Cooper, Max D.

“…Jawless vertebrates are pivotal representatives for studies of the evolution of adaptive immunity due to their unique position in chordate phylogeny. Lamprey…”
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Discriminating gene expression profiles of memory B cell subpopulations by Ehrhardt, Götz R A, Hijikata, Atsushi, Kitamura, Hiroshi, Ohara, Osamu, Wang, Ji-Yang, Cooper, Max D

“…Morphologically and functionally distinct subpopulations of human memory B (B(Mem)) cells are identifiable by either their expression of CD27 or Fc…”
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Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey by Cooper, Max D, Pancer, Zeev, Amemiya, Chris T, Ehrhardt, Götz R. A, Ceitlin, Jill, Larry Gartland, G

“…Although jawless vertebrates are apparently capable of adaptive immune responses, they have not been found to possess the recombinatorial antigen receptors…”
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Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells by Ehrhardt, Götz R A, Hsu, Joyce T, Gartland, Lanier, Leu, Chuen-Miin, Zhang, Shuangyin, Davis, Randall S, Cooper, Max D

“…The FcRH4 transmembrane molecule, a member of the Fc receptor homologue family, can potently inhibit B cell receptor (BCR) signaling. We show that cell surface…”
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Diversity and Function of Adaptive Immune Receptors in a Jawless Vertebrate by Alder, Matthew N, Rogozin, Igor B, Iyer, Lakshminarayan M, Glazko, Galina V, Cooper, Max D, Pancer, Zeev

“…Instead of the immunoglobulin-type antigen receptors of jawed vertebrates, jawless fish have variable lymphocyte receptors (VLRs), which consist of…”
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Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores by Kirchdoerfer, Robert N., Herrin, Brantley R., Han, Byung Woo, Turnbough, Charles L., Cooper, Max D., Wilson, Ian A.

“…Variable lymphocyte receptors (VLRs) are the adaptive immune receptors of jawless fish, which evolved adaptive immunity independent of other vertebrates. In…”
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Selection of the lamprey VLRC antigen receptor repertoire by Holland, Stephen J., Gao, Mingming, Hirano, Masayuki, Iyer, Lakshminarayan M., Luo, Ming, Schorpp, Michael, Cooper, Max D., Aravind, L., Mariuzza, Roy A., Boehm, Thomas

“…The alternative adaptive immune system of jawless vertebrates is based on different isotypes of variable lymphocyte receptors (VLRs) that are composed of…”
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Variable Lymphocyte Receptors in Hagfish by Pancer, Zeev, Saha, Nil Ratan, Kasamatsu, Jun, Suzuki, Takashi, Amemiya, Chris T., Kasahara, Masanori, Cooper, Max D.

“…A previously uncharacterized type of variable lymphocyte receptors (VLR) was identified recently in the Sea lamprey. This jawless vertebrate generates an…”
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Structure and specificity of lamprey monoclonal antibodies by Herrin, Brantley R, Alder, Matthew N, Roux, Kenneth H, Sina, Christina, Ehrhardt, Götz R.A, Boydston, Jeremy A, Turnbough, Charles L. Jr, Cooper, Max D

“…Adaptive immunity in jawless vertebrates (lamprey and hagfish) is mediated by lymphocytes that undergo combinatorial assembly of leucine-rich repeat (LRR) gene…”
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