Search Results - "Cooper, L N"

Targeting c-Myc-Activated Genes with a Correlation Method: Detection of Global Changes in Large Gene Expression Network Dynamics by Remondini, D., O'Connell, B., Intrator, N., Sedivy, J. M., Neretti, N., Castellani, G. C., Cooper, L. N.

“…This work studies the dynamics of a gene expression time series network. The network, which is obtained from the correlation of gene expressions, exhibits…”
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Manufacture of T cells using the Sleeping Beauty system to enforce expression of a CD19-specific chimeric antigen receptor by Singh, H, Moyes, J S E, Huls, M H, Cooper, L J N

“…T cells can be reprogrammed to redirect specificity to tumor-associated antigens (TAAs) through the enforced expression of chimeric antigen receptors (CARs)…”
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Protein signaling and morphological development of the tail fluke in the embryonic beluga whale (Delphinapterus leucas) by Gavazzi, L M, Nair, M, Suydam, R, Usip, S, Thewissen, J G M, Cooper, L N

“…During the land-to-sea transition of cetaceans (whales, dolphins, and porpoises), the hindlimbs were lost and replaced by an elaborate tail fluke that evolved…”
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The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor by Jin, Z, Maiti, S, Huls, H, Singh, H, Olivares, S, Mátés, L, Izsvák, Z, Ivics, Z, Lee, D A, Champlin, R E, Cooper, L J N

“…Sleeping Beauty (SB 3 ) transposon and transposase constitute a DNA plasmid system used for therapeutic human cell genetic engineering. Here we report a…”
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Moving from tinkering in the garage to assembly line production: the manufacture of genetically modified T cells expressing chimeric antigen receptors (CARs) comes on line by Cooper, L J N

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Experimental Investigation of the Quantum Measurement Process Using Electrons in Superfluid Helium by Xing, Y., Sirisky, S., Wei, W., Cooper, L. N., Maris, H. J.

“…We report on mobility measurements of electron bubbles in superfluid helium-4. Electrons are introduced into the liquid from a plasma discharge in the vapor…”
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Immunotherapy for chronic lymphocytic leukemia in the era of BTK inhibitors by Kharfan-Dabaja, M A, Wierda, W G, Cooper, L J N

“…Understanding the pathogenesis of CLL has uncovered a plethora of novel targets for human application of monoclonal antibodies, engineered T cells, or…”
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PET imaging of T cells derived from umbilical cord blood by Singh, H, Najjar, A M, Olivares, S, Nishii, R, Mukhopadhyay, U, Alauddin, M, Manuri, P R, Huls, H, Lee, D A, Dotti, G, Bollard, C, Simmons, P J, Shpall, E J, Champlin, R E, Gelovani, J G, Cooper, L J N

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Antithymidylate resistance enables transgene selection and cell survival for T cells in the presence of 5-fluorouracil and antifolates by Rushworth, D, Alpert, A, Santana-Carrero, R, Olivares, S, Spencer, D, Cooper, L J N

“…Antithymidylates (AThy) constitute a class of drugs used in the treatment of cancers such as lung, colon, breast and pancreas. These drugs inhibit DNA…”
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Carpal Morphology and Function in the Earliest Cetaceans by Gavazzi, L. M., Cooper, L. N., Fish, F. E., Hussain, S. T., Thewissen, J. G. M.

“…During the land-to-water transition in the Eocene epoch, the cetacean skeleton underwent modifications to accommodate life in the seas. These changes are…”
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Measurements of biomass burning influences in the troposphere over southeast Australia during the SAFARI 2000 dry season campaign by Pak, B. C., Langenfelds, R. L., Young, S. A., Francey, R. J., Meyer, C. P., Kivlighon, L. M., Cooper, L. N., Dunse, B. L., Allison, C. E., Steele, L. P., Galbally, I. E., Weeks, I. A.

“…Several studies have observed midtropospheric atmospheric composition anomalies and suggested a link to tropical biomass burning. Such anomalies complicate the…”
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Study of Exotic Ions in Superfluid Helium and the Possible Fission of the Electron Wave Function by Wei, W., Xie, Z., Cooper, L. N., Seidel, G. M., Maris, H. J.

“…An electron in liquid helium forces open a cavity referred as an electron bubble. These objects have been studied in many past experiments. It has been…”
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A Unified Model of NMDA Receptor-Dependent Bidirectional Synaptic Plasticity by Shouval, Harel Z., Bear, Mark F., Cooper, Leon N

“…Synapses in the brain are bidirectionally modifiable, but the routes of induction are diverse. In various experimental paradigms, N-methyl-D-aspartate…”
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Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex by Bienenstock, E L, Cooper, L N, Munro, P W

“…The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework. A synaptic…”
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Synaptic plasticity in visual cortex: comparison of theory with experiment by Clothiaux, E E, Bear, M F, Cooper, L N

“…1. The aim of this work was to assess whether a form of synaptic modification based on the theory of Bienenstock, Cooper, and Munro (BCM) can, with a fixed set…”
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Methods and insights from the characterization of osteoprogenitor cells of bats (Mammalia: Chiroptera) by Ball, H.C., Moussa, F.M., Mbimba, T., Orman, R., Safadi, F.F., Cooper, L.N.

“…Osteoprogenitor cells contribute to the development and maintenance of skeletal tissues. Bats are unique model taxa whose cellular processes are poorly…”
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Adoptive cellular immunotherapy for childhood malignancies by Cooper, L J N

“…Clinical trials have established that T cells have the ability to prevent and treat pathogens and tumors. This is perhaps best exemplified by engraftment of…”
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A Physiological Basis for a Theory of Synapse Modification by Bear, Mark F., Cooper, Leon N, Ebner, Ford F.

“…The functional organization of the cerebral cortex is modified dramatically by sensory experience during early postnatal life. The basis for these…”
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Cholinesterase inhibition and impacts on behavior of the Asian clam, Corbicula fluminea, after exposure to an organophosphate insecticide by Cooper, Naomi L., Bidwell, Joseph R.

“…This study assessed the effects of exposure to an insecticide formulation containing the organophosphate, chlorpyrifos on cholinesterase activity, siphoning…”
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Classification of underwater mammals using feature extraction based on time-frequency analysis and BCM theory by Huynh, Q.Q., Cooper, L.N., Intrator, N., Shouval, H.

“…Underwater mammal sound classification is demonstrated using a novel application of wavelet time-frequency decomposition and feature extraction using a…”
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