Search Results - "Cooper, David"

Subclinical thyroid disease by Cooper, David S, Prof, Biondi, Bernadette, Prof

“…Summary Subclinical thyroid diseases—subclinical hyperthyroidism and subclinical hypothyroidism—are common clinical entities that encompass mild degrees of…”
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Subclinical Hypothyroidism: A Review by Biondi, Bernadette, Cappola, Anne R, Cooper, David S

“…IMPORTANCE: Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal…”
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Clinical xenotransplantation: the next medical revolution? by Ekser, Burcin, MD, Ezzelarab, Mohamed, MD, Hara, Hidetaka, MD, van der Windt, Dirk J, MD, Wijkstrom, Martin, MD, Bottino, Rita, PhD, Trucco, Massimo, Prof, Cooper, David KC, Dr

“…Summary The shortage of organs and cells from deceased individuals continues to restrict allotransplantation. Pigs could provide an alternative source of…”
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The role of genetically engineered pigs in xenotransplantation research by Cooper, David KC, Ekser, Burcin, Ramsoondar, Jagdeece, Phelps, Carol, Ayares, David

“…There is a critical shortage in the number of deceased human organs that become available for the purposes of clinical transplantation. This problem might be…”
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MutationTaster2: mutation prediction for the deep-sequencing age by Schwarz, Jana Marie, Cooper, David N, Schuelke, Markus, Seelow, Dominik

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The varieties of contemplative experience: A mixed-methods study of meditation-related challenges in Western Buddhists by Lindahl, Jared R, Fisher, Nathan E, Cooper, David J, Rosen, Rochelle K, Britton, Willoughby B

“…Buddhist-derived meditation practices are currently being employed as a popular form of health promotion. While meditation programs draw inspiration from…”
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MutationTaster2021 by Steinhaus, Robin, Proft, Sebastian, Schuelke, Markus, Cooper, David N, Schwarz, Jana Marie, Seelow, Dominik

“…Abstract Here we present an update to MutationTaster, our DNA variant effect prediction tool. The new version uses a different prediction model and attains…”
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Antithyroid Drugs by Cooper, David S

“…Antithyroid drugs, which have been available for more than half a century, are important in the management of hyperthyroidism, particularly in patients with…”
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Variation in osteocyte lacunar morphology and density in the human femur — a synchrotron radiation micro-CT study by Carter, Yasmin, Thomas, C. David L, Clement, John G, Peele, Andrew G, Hannah, Kevin, Cooper, David M.L

“…Abstract In recent years there has been growing interest in the spatial properties of osteocytes (including density and morphology) and how these potentially…”
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Xenotransplantation experiments in brain-dead human subjects–A critical appraisal by Cooper, David K.C., Kobayashi, Takaaki

“…Brain-dead human subjects (decedents) were recently introduced as a potential preclinical experimental model in xenotransplantation. Brain death is associated…”
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3D printing PCL/nHA bone scaffolds: exploring the influence of material synthesis techniques by Zimmerling, Amanda, Yazdanpanah, Zahra, Cooper, David M L, Johnston, James D, Chen, Xiongbiao

“…It is known that a number of parameters can influence the post-printing properties of bone tissue scaffolds. Previous research has primarily focused on the…”
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The Clinical Significance of Subclinical Thyroid Dysfunction by Biondi, Bernadette, Cooper, David S

“…Subclinical thyroid disease (SCTD) is defined as serum free T4 and free T3 levels within their respective reference ranges in the presence of abnormal serum…”
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Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease by Cooper, David N., Krawczak, Michael, Polychronakos, Constantin, Tyler-Smith, Chris, Kehrer-Sawatzki, Hildegard

“…Some individuals with a particular disease-causing mutation or genotype fail to express most if not all features of the disease in question, a phenomenon that…”
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Radioiodine for Low-Risk Thyroid Cancer — the Swinging Pendulum by Cooper, David S.

“…Differentiated thyroid cancer, the most common endocrine cancer, has three histologic subtypes: papillary, follicular, and Hürthle-cell cancers, with papillary…”
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The Role of SLAs in Xenotransplantation by Ladowski, Joseph M., Hara, Hidetaka, Cooper, David K.C.

“…Advances in genetic engineering, particularly CRISPR/Cas9, have resulted in the development of a triple glycan-knockout (TKO) pig. There is minimal human…”
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Investigation into relationships between design parameters and mechanical properties of 3D printed PCL/nHAp bone scaffolds by Yazdanpanah, Zahra, Kumar Sharma, Nitin, Zimmerling, Amanda, Cooper, David M L, Johnston, James D, Chen, Xiongbiao

“…Scaffolds are of great importance in tissue engineering applications as they provide a mechanically supportive environment for cellular activity, which is…”
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Management of Graves Disease: A Review by Burch, Henry B, Cooper, David S

“…IMPORTANCE: Graves disease is the most common cause of persistent hyperthyroidism in adults. Approximately 3% of women and 0.5% of men will develop Graves…”
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The Diagnosis and Management of Thyroid Nodules: A Review by Durante, Cosimo, Grani, Giorgio, Lamartina, Livia, Filetti, Sebastiano, Mandel, Susan J, Cooper, David S

“…IMPORTANCE: Thyroid nodules are common, being detected in up to 65% of the general population. This is likely due to the increased use of diagnostic imaging…”
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Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens by Yamamoto, Takayuki, Hara, Hidetaka, Foote, Jeremy, Wang, Liaoran, Li, Qi, Klein, Edwin C, Schuurman, Hendrik Jan, Zhou, Hongmin, Li, Juan, Tector, A Joseph, Zhang, Zhongqiang, Ezzelarab, Mohamed, Lovingood, Ray, Ayares, David, Eckhoff, Devin E, Cooper, David K.C, Iwase, Hayato

“…BACKGROUND.The aims of this study were to evaluate the efficacy of US Food and Drug Administration-approved drugs in genetically engineered pig-to-baboon…”
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Emerging genotype–phenotype relationships in patients with large NF1 deletions by Kehrer-Sawatzki, Hildegard, Mautner, Victor-Felix, Cooper, David N.

“…The most frequent recurring mutations in neurofibromatosis type 1 (NF1) are large deletions encompassing the NF1 gene and its flanking regions ( NF1…”
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