Search Results - "Cooper, Cindy"

What is a pilot or feasibility study? A review of current practice and editorial policy by Arain, Mubashir, Campbell, Michael J, Cooper, Cindy L, Lancaster, Gillian A

“…In 2004, a review of pilot studies published in seven major medical journals during 2000-01 recommended that the statistical analysis of such studies should be…”
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Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable by Whitehead, Amy L, Julious, Steven A, Cooper, Cindy L, Campbell, Michael J

“…Sample size justification is an important consideration when planning a clinical trial, not only for the main trial but also for any preliminary pilot trial…”
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Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study by Griffiths, Paul D, Prof, Bradburn, Michael, MSc, Campbell, Michael J, Prof, Cooper, Cindy L, Prof, Graham, Ruth, PhD, Jarvis, Deborah, BSc, Kilby, Mark D, Prof, Mason, Gerald, MD, Mooney, Cara, MSc, Robson, Stephen C, Prof, Wailoo, Allan, Prof

“…Summary Background In-utero MRI (iuMRI) has shown promise as an adjunct to ultrasound but the comparative diagnostic performance has been poorly defined. We…”
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A study of target effect sizes in randomised controlled trials published in the Health Technology Assessment journal by Rothwell, Joanne C, Julious, Steven A, Cooper, Cindy L

“…When designing a randomised controlled trial (RCT), an important consideration is the sample size required. This is calculated from several components; one of…”
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An Investigation of the Shortcomings of the CONSORT 2010 Statement for the Reporting of Group Sequential Randomised Controlled Trials: A Methodological Systematic Review by Stevely, Abigail, Dimairo, Munyaradzi, Todd, Susan, Julious, Steven A, Nicholl, Jonathan, Hind, Daniel, Cooper, Cindy L

“…It can be argued that adaptive designs are underused in clinical research. We have explored concerns related to inadequate reporting of such trials, which may…”
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SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis by Everard, Mark L, Hind, Daniel, Ugonna, Kelechi, Freeman, Jennifer, Bradburn, Mike, Cooper, Cindy L, Cross, Elizabeth, Maguire, Chin, Cantrill, Hannah, Alexander, John, McNamara, Paul S

“…Acute bronchiolitis is the commonest cause for hospitalisation in infancy. Supportive care remains the cornerstone of current management and no other therapy…”
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MRI in the diagnosis of fetal developmental brain abnormalities: the MERIDIAN diagnostic accuracy study by Griffiths, Paul D, Bradburn, Michael, Campbell, Michael J, Cooper, Cindy L, Embleton, Nicholas, Graham, Ruth, Hart, Anthony R, Jarvis, Deborah, Kilby, Mark D, Lie, Mabel, Mason, Gerald, Mandefield, Laura, Mooney, Cara, Pennington, Rebekah, Robson, Stephen C, Wailoo, Allan

“…Ultrasonography has been the mainstay of antenatal screening programmes in the UK for many years. Technical factors and physical limitations may result in…”
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Estimating the minimum important difference in the DEMQOL instrument in people with dementia by Lee, Ellen C., Wright, Jessica, Walters, Stephen J., Cooper, Cindy L., Mountain, Gail A.

“…Purpose The Dementia-Related Quality of Life (DEMQOL) measure and the DEMQOL-Utility Score (DEMQOL-U) are validated tools for measuring quality of life (QOL)…”
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Factors Associated With Adherence to Self-Managed Aphasia Therapy Practice on a Computer-A Mixed Methods Study Alongside a Randomized Controlled Trial by Harrison, Madeleine, Palmer, Rebecca, Cooper, Cindy

“…Aphasia is a communication disorder often acquired after a stroke. Independent use of specialist aphasia software on a home computer is a form of asynchronous…”
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Recording harms in randomised controlled trials of behaviour change interventions: a qualitative study of UK clinical trials units and NIHR trial investigators by Papaioannou, Diana, Sprange, Kirsty, Hamer-Kiwacz, Sienna, Mooney, Cara, Moody, Gwenllian, Cooper, Cindy

“…Harms, also known as adverse events (AEs), are recorded and monitored in randomised controlled trials (RCTs) to ensure participants' safety. Harms are recorded…”
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The impact of ADHD on the health and well-being of ADHD children and their siblings by Peasgood, Tessa, Bhardwaj, Anupam, Biggs, Katie, Brazier, John E., Coghill, David, Cooper, Cindy L., Daley, David, De Silva, Cyril, Harpin, Val, Hodgkins, Paul, Nadkarni, Amulya, Setyawan, Juliana, Sonuga-Barke, Edmund J. S.

“…Childhood attention-deficit/hyperactivity disorder (ADHD) has been associated with reduced health and well-being of patients and their families. The authors…”
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Exploring the Impact of Patient and Public Involvement in a Cancer Research Setting by Thompson, Jill, Bissell, Paul, Cooper, Cindy L., Armitage, Chris J., Barber, Rosemary

“…An enduring theme in the literature exploring patient and public involvement (PPI) in research has been the focus on evaluating impact, defined usually in…”
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Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT by Thomas, Shirley A, Drummond, Avril Er, Lincoln, Nadina B, Palmer, Rebecca L, das Nair, Roshan, Latimer, Nicholas R, Hackney, Gemma L, Mandefield, Laura, Walters, Stephen J, Hatton, Rachael D, Cooper, Cindy L, Chater, Timothy F, England, Timothy J, Callaghan, Patrick, Coates, Elizabeth, Sutherland, Katie E, Eshtan, Sarah Jacob, Topcu, Gogem

“…There is currently insufficient evidence for the clinical effectiveness and cost-effectiveness of psychological therapies for post-stroke depression. To…”
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Learning from COVID-19 related trial adaptations to inform efficient trial design-a sequential mixed methods study by Chatters, Robin, Cooper, Cindy L, O'Cathain, Alicia, Murphy, Caroline, Lane, Athene, Sutherland, Katie, Burton, Christopher, Cape, Angela, Tunnicliffe, Louis

“…Many clinical trial procedures were often undertaken in-person prior to the COVID-19 pandemic, which has resulted in adaptations to these procedures to enable…”
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Polarization Anisotropy of Multiple Localized Plasmon Resonance Modes in Noble Metal Nanocrescents by Cooper, Cindy T, Rodriguez, Miguel, Blair, Steve, Shumaker-Parry, Jennifer S

“…Multiple localized surface plasmon resonance (LSPR) modes induced in gold and silver nanocrescents exhibit anisotropic behavior with respect to polarization of…”
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A rapid review indicated higher recruitment rates in treatment trials than in prevention trials by Cooper, Cindy L, Hind, Daniel, Duncan, Rosie, Walters, Stephen, Lartey, Adjoa, Lee, Ellen, Bradburn, Mike

“…Abstract Objectives To test the hypothesis that the percentage of patients screened that randomize differs between prevention and therapy trials. Study Design…”
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Mid-Infrared Localized Plasmons through Structural Control of Gold and Silver Nanocrescents by Cooper, Cindy T, Rodriguez, Miguel, Blair, Steve, Shumaker-Parry, Jennifer S

“…Metal nanoarchitectures producing optical responses in the visible and near-infrared form the foundation for most plasmonic studies. In contrast, a relative…”
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Are pilot trials useful for predicting randomisation and attrition rates in definitive studies: A review of publicly funded trials by Cooper, Cindy L, Whitehead, Amy, Pottrill, Edward, Julious, Steven A, Walters, Stephen J

“…Background/aims: External pilot trials are recommended for testing the feasibility of main or confirmatory trials. However, there is little evidence that…”
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Identifying the Active Ingredients of a Computerized Speech and Language Therapy Intervention for Poststroke Aphasia: Multiple Methods Investigation Alongside a Randomized Controlled Trial by Harrison, Madeleine, Palmer, Rebecca, Cooper, Cindy

“…Aphasia is a communication disorder affecting more than one-third of stroke survivors. Computerized Speech and Language Therapy (CSLT) is a complex…”
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Examining the impact of 11 long-standing health conditions on health-related quality of life using the EQ-5D in a general population sample by Wu, Mengjun, Brazier, John E., Kearns, Benjamin, Relton, Clare, Smith, Christine, Cooper, Cindy L.

“…Objectives Health-related quality of life (HRQoL) measures have been increasingly used in economic evaluations for policy guidance. We investigate the impact…”
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