Search Results - "Cooney, N."

L-arginine attenuates Interleukin-1β (IL-1β) induced Nuclear Factor Kappa-Beta (NF-κB) activation in Caco-2 cells by Meng, Qinghe, Cooney, Mitchell, Yepuri, Natesh, Cooney, Robert N

“…Specific nutrients like L-arginine (L-Arg) ameliorate intestinal inflammation, however the exact mechanisms of this effect are unclear. We hypothesized the…”
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Galantamine improves glycemic control and diabetic nephropathy in Leprdb/db mice by Meng, Qinghe, Ma, Julia, Suo, Liye, Pruekprasert, Napat, Chakrapani, Prithi, Cooney, Robert N.

“…Galantamine, a centrally acting acetylcholinesterase inhibitor, has been shown to attenuate inflammation and insulin resistance in patients with metabolic…”
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GTS-21, a selective alpha7 nicotinic acetylcholine receptor agonist, ameliorates diabetic nephropathy in Leprdb/db mice by Meng, Qinghe, Tian, Xinghan, Li, Junwei, Pruekprasert, Napat, Dhawan, Ravi, Holz, George G., Cooney, Robert N.

“…Diabetic nephropathy (DN) is a serious complicating factor in human type 2 diabetes mellitus (T2DM), and it commonly results in end-stage renal disease (ESRD)…”
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Analysis of Estimation Methods for Resting Metabolic Rate in Critically Ill Adults by Frankenfield, David C., Coleman, Abigail, Alam, Shoaib, Cooney, Robert N.

“…Background: Prediction of metabolic rate is an important part of the nutrition assessment of critically ill patients, yet there are limited data regarding the…”
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Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation by Xie, Han, Yepuri, Natesh, Meng, Qinghe, Dhawan, Ravi, Leech, Colin A., Chepurny, Oleg G., Holz, George G., Cooney, Robert N.

“…The cholinergic anti-inflammatory reflex (CAIR) represents an important homeostatic regulatory mechanism for sensing and controlling the body’s response to…”
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Protective effects of glutathione on oxidative injury induced by hydrogen peroxide in intestinal epithelial cells by Ren, Haitao, Meng, Qinghe, Yepuri, Natesh, Du, Xianjin, Sarpong, James Osei, Cooney, Robert N.

“…Reactive oxygen species are increased in multiple gastrointestinal diseases and contribute to their pathogenesis. glutathione (GSH) is an antioxidant that…”
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Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia by Du, Xianjin, Meng, Qinghe, Sharif, Asim, Abdel-Razek, Osama A, Zhang, Linlin, Wang, Guirong, Cooney, Robert N

“…ABSTRACTStaphylococcus aureus pneumonia is an important cause of sepsis which causes gut injury, inflammation, and apoptosis. The surfactant proteins…”
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Enteral administration of bacteria fermented formula in newborn piglets: A high fidelity model for necrotizing enterocolitis (NEC) by Roy, Shreyas K, Meng, Qinghe, Sadowitz, Benjamin D, Kollisch-Singule, Michaela, Yepuri, Natesh, Satalin, Joshua, Gatto, Louis A, Nieman, Gary F, Cooney, Robert N, Clark, David

“…To develop an animal model which replicates neonatal NEC and characterizes the importance of bacterial fermentation of formula and short chain fatty acids…”
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Using the ACGME Milestones for Resident Self-Evaluation and Faculty Engagement by Meier, Andreas H., MD, MEd, Gruessner, Angelika, PhD, Cooney, Robert N., MD

“…Background Since July 2014 General Surgery residency programs have been required to use the Accreditation Council for Graduate Medical Education milestones…”
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Roux-en-Y gastric bypass alters intestinal glucose transport in the obese Zucker rat by Meng, Qinghe, Culnan, Derek M., Ahmed, Tamer, Sun, Mingjie, Cooney, Robert N.

“…IntroductionThe gastrointestinal tract plays a major role in regulating glucose homeostasis and gut endocrine function. The current study examines the effects…”
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Bisindolyl Maleimides and Indolylmaleimide Derivatives—A Review of Their Synthesis and Bioactivity by Cooney, Louise N, O’Shea, Kevin D, Winfield, Hannah J, Cahill, Michael M, Pierce, Larry T, McCarthy, Florence O

“…The evolution of bisindolyl maleimides and indolyl maleimide derivatives and their unique biological activities have stimulated great interest in medicinal…”
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Lineage‐Specific Mesenchymal Stromal Cells Derived from Human iPSCs Showed Distinct Patterns in Transcriptomic Profile and Extracellular Vesicle Production by Winston, Tackla, Song, Yuanhui, Shi, Huaiyu, Yang, Junhui, Alsudais, Munther, Kontaridis, Maria I., Wu, Yaoying, Gaborski, Thomas R., Meng, Qinghe, Cooney, Robert N., Ma, Zhen

“…Over the past decades, mesenchymal stromal cells (MSCs) have been extensively investigated as a potential therapeutic cell source for the treatment of various…”
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Limits of body mass index to detect obesity and predict body composition by Frankenfield, David C, Rowe, William A, Cooney, Robert N, Smith, J.Stanley, Becker, Dolores

“…Body mass index (BMI) is commonly used to identify obesity. In this study, we determined how accurately BMI could determine body composition and identify obese…”
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Roux-en-Y Gastric Bypass Alters Brain Activity in Regions that Underlie Reward and Taste Perception by Thanos, Panayotis K, Michaelides, Mike, Subrize, Mike, Miller, Mike L, Bellezza, Robert, Cooney, Robert N, Leggio, Lorenzo, Wang, Gene-Jack, Rogers, Ann M, Volkow, Nora D, Hajnal, Andras

“…Roux-en-Y gastric bypass (RYGB) surgery is a very effective bariatric procedure to achieve significant and sustained weight loss, yet little is known about the…”
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HIV in young people: characteristics and predictors for late diagnosis of HIV by Cooney, N., Hiransuthikul, N., Lertmaharit, S.

“…Late diagnosis of human immunodeficiency virus (HIV) infection remains a challenging issue, especially in young population, which accounts for approximately…”
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Impact of ASA score misclassification on NSQIP predicted mortality: a retrospective analysis by Helkin, Alex, Jain, Sumeet V, Gruessner, Angelika, Fleming, Maureen, Kohman, Leslie, Costanza, Michael, Cooney, Robert N

“…The ASA physical classification score has a major impact on the observed/expected (O/E) mortality ratio in the NSQIP General Vascular Mortality Model. The…”
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Surgical volume impacts bariatric surgery mortality: A case for centers of excellence by Hollenbeak, Christopher S., PhD, Rogers, Ann M., MD, FACS, Barrus, Bryan, BS, Wadiwala, Irfan, DO, Cooney, Robert N., MD, FACS

“…Background Concerns regarding care quality prompted credentialing processes for bariatric “Centers of Excellence” (COE). It is hypothesized that high-volume…”
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Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat by Culnan, Derek M, Albaugh, Vance, Sun, Mingjie, Lynch, Christopher J, Lang, Charles H, Cooney, Robert N

“…The hindgut hypothesis posits improvements in Type 2 diabetes after gastric bypass surgery are due to enhanced delivery of undigested nutrients to the ileum,…”
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Revisional bariatric surgery: who, what, where, and when? by Radtka, John F., M.D, Puleo, Frances J., M.D, Wang, Li, Ph.D, Cooney, Robert N., M.D

“…Abstract Background Revisional bariatric surgery (RBS) outcomes have been poorly characterized. We compared the RBS and primary bariatric surgery (PBS)…”
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Reactivity to alcohol-related stimuli in the laboratory and in the field: predictors of craving in treated alcoholics by Litt, Mark D., Cooney, Ned L., Morse, Priscilla

“…Aims. (1) To search for predictors of alcohol craving in treated alcoholics; (2) to evaluate the relationship between craving and drinking immediately after…”
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