Search Results - "Cooney, L"

White paper on continuous bioprocessing. May 20-21, 2014 Continuous Manufacturing Symposium by Konstantinov, Konstantin B, Cooney, Charles L

“…There is a growing interest in realizing the benefits of continuous processing in biologics manufacturing, which is reflected by the significant number of…”
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End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation by Mascia, Salvatore, Heider, Patrick L., Zhang, Haitao, Lakerveld, Richard, Benyahia, Brahim, Barton, Paul I., Braatz, Richard D., Cooney, Charles L., Evans, James M. B., Jamison, Timothy F., Jensen, Klavs F., Myerson, Allan S., Trout, Bernhardt L.

“…A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot‐scale plant…”
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Measles virus exits human airway epithelia within dislodged metabolically active infectious centers by Hippee, Camilla E, Singh, Brajesh K, Thurman, Andrew L, Cooney, Ashley L, Pezzulo, Alejandro A, Cattaneo, Roberto, Sinn, Patrick L

“…Measles virus (MeV) is the most contagious human virus. Unlike most respiratory viruses, MeV does not directly infect epithelial cells upon entry in a new…”
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TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus by Brouillette, Rachel B, Phillips, Elisabeth K, Patel, Radhika, Mahauad-Fernandez, Wadie, Moller-Tank, Sven, Rogers, Kai J, Dillard, Jacob A, Cooney, Ashley L, Martinez-Sobrido, Luis, Okeoma, Chioma, Maury, Wendy

“…Lassa virus (LASV) is an Old World arenavirus responsible for hundreds of thousands of infections in West Africa every year. LASV entry into a variety of cell…”
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Concurrent Alcohol and Tobacco Treatment: Effect on Daily Process Measures of Alcohol Relapse Risk by Cooney, Ned L., Litt, Mark D., Sevarino, Kevin A., Levy, Lucienne, Kranitz, Linda S., Sackler, Helen, Cooney, Judith L.

“…Objective: The aim of this study was to compare the effects of alcohol treatment along with concurrent smoking treatment or delayed smoking treatment on…”
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Intratracheal aerosolization of viral vectors to newborn pig airways by Cooney, Ashley L, Sinn, Patrick L

“…Gene therapy for airway diseases requires efficient delivery of nucleic acids to the airways. In small animal models, gene delivery reagents are commonly…”
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piggyBac transposase tools for genome engineering by Li, Xianghong, Burnight, Erin R, Cooney, Ashley L, Malani, Nirav, Brady, Troy, Sander, Jeffry D, Staber, Janice, Wheelan, Sarah J, Joung, J Keith, McCray, Jr, Paul B, Bushman, Frederic D, Sinn, Patrick L, Craig, Nancy L

“…The transposon piggyBac is being used increasingly for genetic studies. Here, we describe modified versions of piggyBac transposase that have potentially…”
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High ionic strength vector formulations enhance gene transfer to airway epithelia by Cooney, Ashley L, Loza, Laura Marquez, Najdawi, Kenan, Brommel, Christian M, McCray, Paul B, Sinn, Patrick L

“…Abstract A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelia to achieve therapeutic…”
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A review on the continuous blending of powders by Pernenkil, Lakshman, Cooney, Charles L.

“…This review traces the underlying theory and practice of continuous powder blending to provide a foundation for its development. Apart from reviewing the…”
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role of T helper type 17 cells in inflammatory arthritis by Sarkar, S, Cooney, L.A, Fox, D.A

“…While T cells have been implicated in the pathogenesis of inflammatory arthritis for more than three decades, the focus on the T helper type 17 (Th17) subset…”
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Prospective Analysis of Early Lapse to Drinking and Smoking Among Individuals in Concurrent Alcohol and Tobacco Treatment by Holt, Laura J., Litt, Mark D., Cooney, Ned L.

“…The aims of the current study were to examine, prospectively, (a) dynamic changes in affective state, self-efficacy, and urge in the hours before initial…”
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Alcohol and Tobacco Cessation in Alcohol-Dependent Smokers: Analysis of Real-Time Reports by Cooney, Ned L, Litt, Mark D, Cooney, Judith L, Pilkey, David T, Steinberg, Howard R, Oncken, Cheryl A

“…Alcohol-tobacco interactions and relapse precipitants were examined among alcohol-dependent smokers in a trial of concurrent alcohol and tobacco treatment…”
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A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients by Inouye, Sharon K, Bogardus, Sidney T, Charpentier, Peter A, Leo-Summers, Linda, Acampora, Denise, Holford, Theodore R, Cooney, Leo M

“…Delirium, also known as acute confusional state, is a common, serious, and potentially preventable source of morbidity and mortality among hospitalized older…”
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Impact of the Food and Drug Administration (FDA) safety communication on morcellation on surgical practice and perioperative morbidity following myomectomy by Stentz, N.C, Cooney, L, Sammel, M.D, Shah, D.K

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Association between psychosocial factors and co-morbid cigarette smoking and alcohol use in a population experiencing homelessness by Onigbogi, Olanrewaju, Pratt, Rebekah, Luo, Xianghua, Everson-Rose, Susan A., Cooney, Ned L., Specker, Sheila, Okuyemi, Kolawole

“…•Psychosocial variables were associated with heaviness of smoking and alcohol consumption.•Frequency of homelessness was associated with greater anxiety scores…”
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Effects of exercise intervention on myocardial function in type 2 diabetes by Hordern, M D, Coombes, J S, Cooney, L M, Jeffriess, L, Prins, J B, Marwick, T H

“…To identify the effects of a 1-year exercise intervention on myocardial dysfunction in patients with type 2 diabetes mellitus (T2DM). Randomised controlled…”
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Gene Therapy Potential for Genetic Disorders of Surfactant Dysfunction by Cooney, Ashley L, Wambach, Jennifer A, Sinn, Patrick L, McCray, Jr, Paul B

“…Pulmonary surfactant is critically important to prevent atelectasis by lowering the surface tension of the alveolar lining liquid. While respiratory distress…”
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Intrauterine devices placed at oocyte retrieval are an acceptable method of contraception in women with cancer by Cooney, L, Kiskis, E, Efymow, B, Gracia, C

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Consequences of driving cessation : Decreased out-of-home activity levels by MAROTTOLI, Richard A, MENDES DE LEON, Carlos F, GLASS, Thomas A, WILLIAMS, Christianna S, COONEY, Leo M, BERKMAN, Lisa F

“…Increasing age, socioeconomic factors, and declining function and health have been linked to driving cessation, but little is known about the consequences of…”
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Give Them Prizes, and They Will Come: Contingency Management for Treatment of Alcohol Dependence by Petry, Nancy M, Martin, Bonnie, Cooney, Judith L, Kranzler, Henry R

“…This study evaluated the efficacy of a contingency management (CM) procedure that provided opportunities to win prizes as reinforcers. At intake to outpatient…”
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