Search Results - "Cooney, A."

Prostate cancer in young men: an important clinical entity by Salinas, Claudia A., Tsodikov, Alex, Ishak-Howard, Miriam, Cooney, Kathleen A.

“…Key Points The incidence of prostate cancer in young men (aged ≤55 years) has increased sharply over the past two decades, making early-onset prostate cancer…”
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Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012 by Hussain, Maha, Daignault-Newton, Stephanie, Twardowski, Przemyslaw W, Albany, Costantine, Stein, Mark N, Kunju, Lakshmi P, Siddiqui, Javed, Wu, Yi-Mi, Robinson, Dan, Lonigro, Robert J, Cao, Xuhong, Tomlins, Scott A, Mehra, Rohit, Cooney, Kathleen A, Montgomery, Bruce, Antonarakis, Emmanuel S, Shevrin, Daniel H, Corn, Paul G, Whang, Young E, Smith, David C, Caram, Megan V, Knudsen, Karen E, Stadler, Walter M, Feng, Felix Y, Chinnaiyan, Arul M

“…Purpose To determine whether cotargeting poly (ADP-ribose) polymerase-1 plus androgen receptor is superior to androgen receptor inhibition in metastatic…”
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Elevated Risk of Prostate Cancer Among Men With Lynch Syndrome by Raymond, Victoria M, Mukherjee, Bhramar, Wang, Fei, Huang, Shu-Chen, Stoffel, Elena M, Kastrinos, Fay, Syngal, Sapna, Cooney, Kathleen A, Gruber, Stephen B

“…Prostate cancer has been described as a component tumor of Lynch syndrome (LS), with tumors obtained from mutation carriers demonstrating the DNA mismatch…”
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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors by Hovelson, Daniel H, McDaniel, Andrew S, Cani, Andi K, Johnson, Bryan, Rhodes, Kate, Williams, Paul D, Bandla, Santhoshi, Bien, Geoffrey, Choppa, Paul, Hyland, Fiona, Gottimukkala, Rajesh, Liu, Guoying, Manivannan, Manimozhi, Schageman, Jeoffrey, Ballesteros-Villagrana, Efren, Grasso, Catherine S, Quist, Michael J, Yadati, Venkata, Amin, Anmol, Siddiqui, Javed, Betz, Bryan L, Knudsen, Karen E, Cooney, Kathleen A, Feng, Felix Y, Roh, Michael H, Nelson, Peter S, Liu, Chia-Jen, Beer, David G, Wyngaard, Peter, Chinnaiyan, Arul M, Sadis, Seth, Rhodes, Daniel R, Tomlins, Scott A

“…Abstract Next-generation sequencing (NGS) has enabled genome-wide personalized oncology efforts at centers and companies with the specialty expertise and…”
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REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants by Ioannidis, Nilah M., Rothstein, Joseph H., Pejaver, Vikas, Middha, Sumit, McDonnell, Shannon K., Baheti, Saurabh, Musolf, Anthony, Li, Qing, Holzinger, Emily, Karyadi, Danielle, Cannon-Albright, Lisa A., Teerlink, Craig C., Stanford, Janet L., Isaacs, William B., Xu, Jianfeng, Cooney, Kathleen A., Lange, Ethan M., Schleutker, Johanna, Carpten, John D., Powell, Isaac J., Cussenot, Olivier, Cancel-Tassin, Geraldine, Giles, Graham G., MacInnis, Robert J., Maier, Christiane, Hsieh, Chih-Lin, Wiklund, Fredrik, Catalona, William J., Foulkes, William D., Mandal, Diptasri, Eeles, Rosalind A., Kote-Jarai, Zsofia, Bustamante, Carlos D., Schaid, Daniel J., Hastie, Trevor, Ostrander, Elaine A., Bailey-Wilson, Joan E., Radivojac, Predrag, Thibodeau, Stephen N., Whittemore, Alice S., Sieh, Weiva

“…The vast majority of coding variants are rare, and assessment of the contribution of rare variants to complex traits is hampered by low statistical power and…”
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Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring by Cooney, Craig A, Dave, Apurva A, Wolff, George L

“…This study was designed to determine if maternal dietary methyl supplements increase DNA methylation and methylation-dependent epigenetic phenotypes in…”
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Defining a "Good Death": Exploring Veterinarians' Perceptions of Companion Animal Euthanasia by Kogan, Lori R, Cooney, Kathleen A

“…This study was designed to determine how veterinarians define a good euthanasia experience. This information is used to generate a working definition of…”
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Somatic Single Hits Inactivate the X-Linked Tumor Suppressor FOXP3 in the Prostate by Wang, Lizhong, Liu, Runhua, Li, Weiquan, Chen, Chong, Katoh, Hiroto, Chen, Guo-Yun, McNally, Beth, Lin, Lin, Zhou, Penghui, Zuo, Tao, Cooney, Kathleen A., Liu, Yang, Zheng, Pan

“…Despite clear epidemiological and genetic evidence for X-linked prostate cancer risk, all prostate cancer genes identified are autosomal. Here, we report…”
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Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin by Xiao, Qian, Mears, Joseph, Nathan, Aparna, Ishigaki, Kazuyoshi, Baglaenko, Yuriy, Lim, Noha, Cooney, Laura A., Harris, Kristina M., Anderson, Mark S., Fox, David A., Smilek, Dawn E., Krueger, James G., Raychaudhuri, Soumya

“…Psoriasis is a chronic, systemic inflammatory condition primarily affecting skin. While the role of the immune compartment (e.g., T cells) is well established,…”
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Sensitivity and resistance to regulation by IL-4 during Th17 maturation by Cooney, Laura A, Towery, Keara, Endres, Judith, Fox, David A

“…Th17 cells are highly pathogenic in a variety of immune-mediated diseases, and a thorough understanding of the mechanisms of cytokine-mediated suppression of…”
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A comparison of the performance and stability of Pd/BCC metal composite membranes for hydrogen purification by COONEY, Daniel A, DOUGLAS WAY, J, WOLDEN, Colin A

“…Composite membranes were fabricated by sputtering 100 nm of Pd on to both sides of dense BCC metal foils (V, Ta, Nb). Under pure H sub(2) gas testing at 500…”
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Admixture Mapping Identifies 8q24 as a Prostate Cancer Risk Locus in African-American Men by Freedman, Matthew L., Haiman, Christopher A., Patterson, Nick, McDonald, Gavin J., Tandon, Arti, Waliszewska, Alicja, Penney, Kathryn, Steen, Robert G., Ardlie, Kristin, John, Esther M., Oakley-Girvan, Ingrid, Whittemore, Alice S., Cooney, Kathleen A., Ingles, Sue A., Altshuler, David, Henderson, Brian E., Reich, David

“…A whole-genome admixture scan in 1,597 African Americans identified a 3.8 Mb interval on chromosome 8q24 as significantly associated with susceptibility to…”
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Multiple regions within 8q24 independently affect risk for prostate cancer by McDonald, Gavin J, Reich, David, Greenway, Steven C, Neubauer, Julie, Kolonel, Laurence N, Cooney, Kathleen A, John, Esther M, Freedman, Matthew L, Frasco, Melissa, Altshuler, David, Waliszewska, Alicja, Pike, Malcolm C, Wong, David, Oakley-Girvan, Ingrid, Pooler, Loreall C, Ardlie, Kristin, Tandon, Arti, Myers, Simon R, Patterson, Nick, Le Marchand, Loic, Henderson, Brian E, Whittemore, Alice S, Haiman, Christopher A, Stram, Daniel O, Schirmer, Christine, Ingles, Sue A

“…After the recent discovery that common genetic variation in 8q24 influences inherited risk of prostate cancer, we genotyped 2,973 SNPs in up to 7,518 men with…”
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The relationship between quadriceps angle and tibial tuberosity–trochlear groove distance in patients with patellar instability by Cooney, A. D., Kazi, Z., Caplan, N., Newby, M., St Clair Gibson, A., Kader, D. F.

“…Purpose The quadriceps angle (Q-angle) represents the angle between the vector of action of the quadriceps and the patellar tendon. An increased Q-angle has…”
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Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene by Staber, J M, Pollpeter, M J, Anderson, C-G, Burrascano, M, Cooney, A L, Sinn, P L, Rutkowski, D T, Raschke, W C, McCray, P B

“…Current therapies for hemophilia A include frequent prophylactic or on-demand intravenous factor treatments which are costly, inconvenient and may lead to…”
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Adaptation of the socioecological model to address disparities in engagement of Black men in prostate cancer genetic testing by Leader, Amy E, Rebbeck, Timothy R, Oh, William K, Patel, Alpa V, Winer, Eric P, Bailey, LeeAnn O, Gomella, Leonard G, Lumpkins, Crystal Y, Garraway, Isla P, Aiello, Lisa B, Baskin, Monica L, Cheng, Heather H, Cooney, Kathleen A, Ganzak, Amanda, George, Daniel J, Halabi, Susan, Hathaway, Feighanne, Healy, Claire, Kim, Joseph W, Leapman, Michael S, Loeb, Stacy, Maxwell, Kara N, McNair, Christopher, Morgan, Todd M, Prindeville, Breanne, Soule, Howard R, Steward, Whitney L, Suttiratana, Sakinah C, Taplin, Mary-Ellen, Yamoah, Kosj, Fortune, Thierry, Bennett, Kris, Blanding-Godbolt, Joshua, Gross, Laura, Giri, Veda N

“…Black men consistently have higher rates of prostate cancer (PCA)- related mortality. Advances in PCA treatment, screening, and hereditary cancer assessment…”
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Anionic Pulmonary Surfactant Lipid Treatment Inhibits Rhinovirus A Infection of the Human Airway Epithelium by Numata, Mari, Sajuthi, Satria, Bochkov, Yury A, Loeffler, Jessica, Everman, Jamie, Vladar, Eszter K, Cooney, Riley A, Reinhardt, Richard Lee, Liu, Andrew H, Seibold, Max A, Voelker, Dennis R

“…Rhinoviruses (RVs) are major instigators of acute exacerbations of asthma, COPD, and other respiratory diseases. RVs are categorized into three species (RV-A,…”
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Assessing the benefits and usefulness of Schwartz Centre rounds in second-year medical students using clinical educator-facilitated group work session: not just "a facilitated moan" by Smith, J, Stewart, M G, Foggin, E, Mathews, S, Harris, J, Thomas, P, Cooney, A, Stocker, C J

“…An experiential curriculum exposing medical students to the clinic early has many benefits but comes with the emotional stress this environment engenders…”
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role of T helper type 17 cells in inflammatory arthritis by Sarkar, S, Cooney, L.A, Fox, D.A

“…While T cells have been implicated in the pathogenesis of inflammatory arthritis for more than three decades, the focus on the T helper type 17 (Th17) subset…”
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Racial differences in patterns of treatment among men diagnosed with de novo advanced prostate cancer: A SEER‐Medicare investigation by Beebe‐Dimmer, Jennifer L., Ruterbusch, Julie J., Cooney, Kathleen A., Bolton, Adam, Schwartz, Kendra, Schwartz, Ann G., Heath, Elisabeth

“…Purpose Approximately 5% of men were initially diagnosed with (also referred to as de novo) advanced stage prostate cancer and experience far poorer survival…”
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