Search Results - "Coon, J S"

ERβ- and Prostaglandin E2-Regulated Pathways Integrate Cell Proliferation via Ras-like and Estrogen-Regulated Growth Inhibitor in Endometriosis by Monsivais, D, Dyson, M. T, Yin, P, Coon, J. S, Navarro, A, Feng, G, Malpani, S. S, Ono, M, Ercan, C. M, Wei, J. J, Pavone, M. E, Su, E, Bulun, S. E

“…In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2…”
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Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro by HE, X, POOL, M, DARCY, K. M, LIM, S. B, AUERSPERG, N, COON, J. S, BECK, W. T

“…Polypyrimidine tract-binding protein (PTB) is an RNA-binding protein with multiple functions in the regulation of RNA processing and IRES-mediated translation…”
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Sunitinib and bevacizumab for first-line treatment of metastatic renal cell carcinoma: a systematic review and indirect comparison of clinical effectiveness by Thompson Coon, J S, Liu, Z, Hoyle, M, Rogers, G, Green, C, Moxham, T, Welch, K, Stein, K

“…Background: Two new agents have recently been licensed for use in the treatment of metastatic renal cell carcinoma (RCC) in Europe. This paper aims to…”
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Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer by He, X, Arslan, A D, Pool, M D, Ho, T-T, Darcy, K M, Coon, J S, Beck, W T

“…Our previous study revealed that two splicing factors, polypyrimidine tract-binding protein (PTB) and SRp20, were upregulated in epithelial ovarian cancer…”
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Adenosine A1 receptor, a target and regulator of estrogen receptorα action, mediates the proliferative effects of estradiol in breast cancer by Lin, Z, Yin, P, Reierstad, S, O'Halloran, M, Coon V, J S, Pearson, E K, Mutlu, G M, Bulun, S E

“…Estrogen receptor-α (ERα) and its ligand estradiol (E2) has critical roles in breast cancer growth and are key therapeutic targets. In this study, we report a…”
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A multi-analyte serum test for the detection of non-small cell lung cancer by Farlow, E C, Vercillo, M S, Coon, J S, Basu, S, Kim, A W, Faber, L P, Warren, W H, Bonomi, P, Liptay, M J, Borgia, J A

“…Background: In this study, we appraised a wide assortment of biomarkers previously shown to have diagnostic or prognostic value for non-small cell lung cancer…”
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A Chemical Inhibitor of p53 that Protects Mice from the Side Effects of Cancer Therapy by Komarov, Pavel G., Komarova, Elena A., Kondratov, Roman V., Christov-Tselkov, Konstantin, Coon, John S., Chernov, Mikhail V., Gudkov, Andrei V.

“…Chemotherapy and radiation therapy for cancer often have severe side effects that limit their efficacy. Because these effects are in part determined by…”
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Glucocorticoid-induction of hypothalamic aromatase via its brain-specific promoter by Brooks, D.C., Zhao, H., Yilmaz, M.B., Coon V, J.S., Bulun, S.E.

“…► We demonstrate glucocorticoid induction of Cyp19a1 via its brain-specific promoter. ► Inhibition of GR via siRNA or RU-486 ablates aromatase stimulation. ►…”
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Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells by Moy, I, Todorović, V, Dubash, A D, Coon, J S, Parker, J B, Buranapramest, M, Huang, C C, Zhao, H, Green, K J, Bulun, S E

“…Aromatase inhibitors (AIs) are the standard endocrine therapy for postmenopausal breast cancer; however, currently used biomarkers, such as, estrogen…”
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Cyclin D1 expression in squamous cell carcinomas of the head and neck and in oral mucosa in relation to proliferation and apoptosis by V M Kotelnikov, J S Coon, 4th, S Mundle, S Kelanic, S LaFollette, I V Taylor S, J Hutchinson, W Panje, D D Caldarelli, H D Preisler

“…Deregulation of expression of the cell cycle regulator cyclin D1 (cD1) may be responsible for rapid proliferation of squamous cell carcinoma of the head and…”
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Comparison of solutol HS 15, Cremophor EL and novel ethoxylated fatty acid surfactants as multidrug resistance modification agents by Buckingham, L E, Balasubramanian, M, Emanuele, R M, Clodfelter, K E, Coon, J S

“…Some well-known fatty acid ester surfactants, e.g., Cremophor EL and Solutol HS 15, are modulators of multidrug resistance in vitro and in vivo. Because they…”
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Accuracy of histone H3 messenger RNA in situ hybridization for the assessment of cell proliferation in human tissues by KOTELNIKOV, V, CASS, L, COON, J. S, SPAULDING, D, PREISLER, H. D

“…Histone H3 mRNA in situ hybridization was compared to a reference method, iododeoxyuridine (IdUrd) immunohistochemistry of tissues labeled in vivo, as a means…”
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Prognostic Significance of p27 Expression in Carcinoma of the Oral Cavity and Oropharynx by Venkatesan, T. K., Kuropkat, Christiane, Caldarelli, David D., Panje, William R., Hutchinson Jr, James C., Chen, Shande, Coon, John S.

“…Objective: To study the role of p27, a cyclin‐dependent kinase inhibitor, as a prognostic indicator in squamous cell carcinoma of the oral cavity and…”
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Detection of tumor cells in the bone marrow, peripheral blood, and apheresis products of breast cancer patients using flow cytometry by Simpson, S J, Vachula, M, Kennedy, M J, Kaizer, H, Coon, J S, Ghalie, R, Williams, S, Van Epps, D

“…One of the possible drawbacks to autologous bone marrow (BM) and peripheral blood progenitor cell (PBPC) transplantation in breast cancer patients is the…”
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P-glycoproteins in pathology: the multidrug resistance gene family in humans by Weinstein, R S, Kuszak, J R, Kluskens, L F, Coon, J S

“…Many cancers do not respond to chemotherapy on primary exposure to drugs, thus manifesting intrinsic drug resistance. Other cancers that do initially respond…”
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Temperature Alters Lipopolysaccharide‐Induced Cytokine Secretion by RAW 264.7 Cells by Kirkley, J. E., Thompson, B. J., Coon, J. S.

“…Local and systemic temperature change is associated with the immune response to infection, but the role of temperature remains poorly understood. To study the…”
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Abnormalities of molecular regulators of proliferation and apoptosis in carcinoma of the oral cavity and oropharynx by Kuropkat, Christiane, Venkatesan, T.K, Caldarelli, D.D, Panje, W.R, Hutchinson, J, Preisler, H.D, Coon, J.S, Werner, J.A

“…Objective: Abnormalities in genes regulating cell proliferation and death may affect disease outcome in squamous cell carcinoma (SCC) of the head and neck…”
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Continued malignant cell proliferation in head and neck tumors during cytotoxic therapy by H D Preisler, V M Kotelnikov, S LaFollette, S Taylor, 4th, S Mundle, N Wood, J S Coon, 4th, J Hutchinson, W Panje, D D Caldarelli, K Griem

“…The effect of cytotoxic therapy on the proliferation of squamous cell carcinoma of the head and neck in vivo in patients was evaluated before and 15-35 days…”
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Prognostic significance of Bcl-2 expression in localized squamous cell carcinoma of the head and neck by Friedman, M, Grey, P, Venkatesan, T K, Bloch, I, Chawla, P, Caldarelli, D D, Coon, J S

“…This study was conducted to determine whether Bcl-2 overexpression in localized squamous cell carcinoma of the head and neck (SCCHN) might serve as a marker…”
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Regulators of Proliferation and Apoptosis in Carcinoma of the Larynx by Whisler, Laura C., Wood, Nancy B., Caldarelli, David D., Hutchinson, James C., Panje, William R., Friedman, Michael, Preisler, Harvey D., Leurgans, Sue, Nowak, Jan, Coon, John S.

“…Expression of interrelated gene products regulating cell proliferation and apoptosis may be disordered in squamous cell carcinoma (SCC) of the larynx compared…”
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