Search Results - "Coombes, Megan"

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  1. 1

    Longitudinal adherence to colorectal cancer screening guidelines by Cyhaniuk, Anissa, Coombes, Megan E

    Published in The American journal of managed care (01-02-2016)
    “…To describe adherence with United States Preventive Services Task Force (USPSTF) colorectal cancer (CRC) screening recommendations over a 10-year period in a…”
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    Journal Article
  2. 2

    Adjuvant therapy for completely resected stage II colon cancer by Figueredo, Alvaro, Coombes, Megan E, Mukherjee, Som

    Published in Cochrane database of systematic reviews (16-07-2008)
    “…Colon cancer is potentially curable by surgery. Although adjuvant chemotherapy benefits patients with stage III disease, there is uncertainty of such benefit…”
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    Journal Article
  3. 3

    A population-based comparison of treatment patterns, resource utilization, and costs by cancer stage for Ontario patients with hormone receptor-positive/HER2-negative breast cancer by Brezden-Masley, Christine, Fathers, Kelly E., Coombes, Megan E., Pourmirza, Behin, Xue, Cloris, Jerzak, Katarzyna J.

    Published in Breast cancer research and treatment (01-01-2021)
    “…Purpose To update and expand on data related to treatment, resource utilization, and costs by cancer stage in Canadian patients with hormone receptor-positive…”
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  4. 4

    A population-based comparison of treatment, resource utilization, and costs by cancer stage for Ontario patients with HER2-positive breast cancer by Brezden-Masley, Christine, Fathers, Kelly E., Coombes, Megan E., Pourmirza, Behin, Xue, Cloris, Jerzak, Katarzyna J.

    Published in Breast cancer research and treatment (01-02-2021)
    “…Purpose We sought to expand the currently limited, Canadian, population-based data on the characteristics, treatment pathways, and health care costs according…”
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    Journal Article
  5. 5

    Herceptin® (trastuzumab) in HER2-positive early breast cancer: a systematic review and cumulative network meta-analysis by Wilson, Florence R, Coombes, Megan E, Brezden-Masley, Christine, Yurchenko, Mariya, Wylie, Quinlan, Douma, Reuben, Varu, Abhishek, Hutton, Brian, Skidmore, Becky, Cameron, Chris

    Published in Systematic reviews (14-11-2018)
    “…Originator trastuzumab (Herceptin®; H) is an antibody-targeted therapy to treat patients with human epidermal growth factor receptor 2-positive (HER2+) early…”
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    Journal Article
  6. 6

    A population‐based comparison of treatment patterns, resource utilization, and costs by cancer stage for Ontario patients with triple‐negative breast cancer by Brezden‐Masley, Christine, Fathers, Kelly E., Coombes, Megan E., Pourmirza, Behin, Xue, Cloris, Jerzak, Katarzyna J.

    Published in Cancer medicine (Malden, MA) (01-10-2020)
    “…Background There have been few publications exploring the characteristics, treatment pathways, and health‐care costs by stage in patients with a…”
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    Journal Article
  7. 7

    Herceptin® (trastuzumab) in HER2-positive early breast cancer: protocol for a systematic review and cumulative network meta-analysis by Wilson, Florence R, Coombes, Megan E, Wylie, Quinlan, Yurchenko, Mariya, Brezden-Masley, Christine, Hutton, Brian, Skidmore, Becky, Cameron, Chris

    Published in Systematic reviews (10-10-2017)
    “…Human epidermal growth factor receptor 2-positive (HER2+) breast cancer is an aggressive disease that makes up about 20% of all invasive breast cancers. HER2+…”
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    Journal Article
  8. 8

    A qualitative study evaluating causality attribution for serious adverse events during early phase oncology clinical trials by Mukherjee, Som D., Coombes, Megan E., Levine, Mitch, Cosby, Jarold, Kowaleski, Brenda, Arnold, Andrew

    Published in Investigational new drugs (01-10-2011)
    “…Summary Background In early phase oncology trials, novel targeted therapies are increasingly being tested in combination with traditional agents creating…”
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    Journal Article
  9. 9

    Examination for Sexual Assault: Evaluating the Literature for Indicators of Women-Centered Care by McGregor, Margaret J., Mont, Janice Du, White, Deborah, Coombes, Megan E.

    Published in Health care for women international (01-01-2009)
    “…This study aimed to assess the extent to which recent peer-reviewed published literature on the acute management of sexual assault was women-centered. We…”
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  10. 10

    Abstract PS9-55: Subcutaneous fixed-dose combination of pertuzumab and trastuzumab for the treatment of metastatic breast cancer in Canada - a budget impact analysis by Sripada, Kaushik, Manjrekar, Siddhi, Klein-Panneton, Kristoph, Coombes, Megan, Ferrario, Cristiano

    Published in Cancer research (Chicago, Ill.) (15-02-2021)
    “…Background: Recently, the FeDeriCa trial investigated a fixed-dose combination (FDC) of Perjeta and Herceptin (PH), administered by subcutaneous (SC)…”
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    Journal Article
  11. 11

    Abstract P2-08-23: A population-based study examining the epidemiology, treatment patterns and resource utilization by stage in Ontario patients with HER2+ breast cancer by Brezden-Masley, Christine, Fathers, Kelly Elizabeth, Coombes, Megan, Xue, Cloris, Pourmirza, Behin, Jerzak, Katarzyna J.

    Published in Cancer research (Chicago, Ill.) (15-02-2020)
    “…Background: Since the discovery of HER2-targeted treatments for HER2+ breast cancer (BC), women with this historically poor-prognosis subtype have benefitted…”
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    Journal Article
  12. 12

    Abstract P6-13-02: Subcutaneous trastuzumab for the treatment of HER2+ breast cancer in Canada: A cost-minimization study by Coombes, Megan, Yin, Lori, Liu, Ingrid, Shek, Norman, Rusu, Flavia, Mukherjee, Som

    Published in Cancer research (Chicago, Ill.) (15-02-2020)
    “…Background: There is an urgent need to alleviate the pressure on healthcare resources and decrease treatment burden for patients. Recently, a new fixed dose…”
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  13. 13

    Abstract P2-08-08: A population-based study examining the epidemiology, treatment patterns and resource utilization by stage in Ontario patients with triple negative breast cancer by Brezden-Masley, Christine, Fathers, Kelly Elizabeth, Coombes, Megan, Xue, Cloris, Pourmirza, Behin, Jerzak, Katarzyna J.

    Published in Cancer research (Chicago, Ill.) (15-02-2020)
    “…Background: There is limited current data on the incidence, clinical characteristics, treatment patterns, and resource utilization in breast cancer patients…”
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    Journal Article
  14. 14

    Does antibiotic exposure during infancy lead to development of asthma?: a systematic review and metaanalysis by Marra, Fawziah, Lynd, Larry, Coombes, Megan, Richardson, Kathryn, Legal, Michael, Fitzgerald, J Mark, Marra, Carlo A

    Published in Chest (01-03-2006)
    “…To determine the association between antibiotic exposure in the first year of life and the development of childhood asthma. Metaanalysis of observational…”
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  15. 15

    Who's the fairest of them all? Which provincial pharmacare model would best protect Canadians against catastrophic drug costs? by Coombes, Megan E, Morgan, Steven G, Barer, Morris L, Pagliccia, Nino

    “…Public prescription drug plans vary markedly across Canada. To address perceived inequities in coverage across provinces, the February 2003 First Ministers'…”
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    Journal Article
  16. 16

    Income-Based Drug Coverage in British Columbia: Towards an Understanding of the Policy by Morgan, Steve, Coombes, Megan

    Published in Healthcare policy (01-11-2006)
    “…Background and Objectives In May 2003, the government of British Columbia adopted income-based pharmacare, replacing an age-based drug benefits program…”
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  17. 17