Search Results - "Coombes, D"

Evolution and parathyroid surgery by Scott-Coombes, D M

Get full text

Management of thyroid cancer: United Kingdom National Multidisciplinary Guidelines by Mitchell, A L, Gandhi, A, Scott-Coombes, D, Perros, P

“…This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper provides…”
Get more information

Osteopontin splice variants and polymorphisms in cancer progression and prognosis by Briones-Orta, Marco Antonio, Avendaño-Vázquez, S. Eréndira, Aparicio-Bautista, Diana Ivette, Coombes, Jason D., Weber, Georg F., Syn, Wing-Kin

“…Osteopontin (OPN) is an extracellular matrix protein that is overexpressed in various cancers and promotes oncogenic features including cell proliferation,…”
Get full text

Intraoperative Parathyroid Hormone Assay Remains Predictive of Cure in Renal Impairment in Patients with Single Parathyroid Adenomas by Egan, R. J., Iliff, H., Stechman, M. J., Scott-Coombes, D. M.

“…Background Parathyroid hormone (PTH) has a short half-life and is cleared by the liver and kidneys. This study examined whether declining estimated glomerular…”
Get full text

A 15-year experience: intraoperative parathyroid hormone assay for the management of primary hyperparathyroidism in a UK endocrine surgical unit by Patel, N, Whittet, C, Zhao, D, Rees, J, Stechman, MJ, Scott-Coombes, DM

“…Purpose This study aims to evaluate the outcomes of first-time parathyroidectomy for primary hyperparathyroidism using intraoperative PTH (IOPTH) assay in the…”
Get full text

Is Unilateral Neck Surgery Feasible in Patients with Sporadic Primary Hyperparathyroidism and Double Negative Localisation? by Scott-Coombes, D. M., Rees, J., Jones, G., Stechman, M. J.

“…Introduction Ultrasound and Tc99mMIBI scans are used to localise parathyroid tumours in sporadic primary hyperparathyroidism (pHPT). Intra-operative PTH…”
Get full text

Prediction of long-term dependence on vitamin D analogues following total thyroidectomy for Graves' disease by Patel, N, Mahoney, R, Scott-Coombes, D, Stechman, M

“…This study aimed to identify patients at risk of long-term hypocalcaemia following total thyroidectomy for Graves' disease, and to determine the thresholds of…”
Get full text

Outcomes of surgery for benign and malignant adrenal disease from the British Association of Endocrine and Thyroid Surgeons' national registry by Patel, N., Egan, R. J., Carter, B. R., Scott‐Coombes, D. M., Stechman, M. J., Afzaal, A., Akhtar, I., Akyol, M., Anderson, I., Aspinall, S., Balasubramanian, S., Banga, N., Bliss, R., Brindle, R., Carpenter, R., Cave‐Bigley, D., Chadwick, D., Collins, R., Craig, W., Cvasciuc, T., Doran, H., Dunn, J., Eatock, F., El‐Saify, W., Evans, A., Fraser, S., Galata, G., Greaney, M. G., Guy, A., Hardy, R., Harrison, B., Houghton, A., Hubbard, A., Jeddy, T., Kirkby‐Bott, J., Krukowski, Z., Kurup, V., Kurzawinski, T., Lansdown, M., Lennard, T. M. J., Lim, B., Maddox, P., Mihai, R., Nicholson, M., Palazzo, F., Parrott, N., Parvanta, L., Rew, D., Sadler, G., Schulte, K. M., Sharma, A., Shore, S., Sinha, P., Skene, A., Smellie, J., Smith, D., Sutcliffe, R., Thomas, M., Thomas, P., Thomas, W. E. G., Titus, A., Tomlinson, M., Truran, P., Ubhi, C., Uppal, H., Waghorn, A., Walls, G., Williams, S., Zammitt, C.

“…Background This study investigated the indications, procedures and outcomes for adrenal surgery from the UK Registry of Endocrine and Thyroid Surgery database…”
Get full text

Impact of a clinical pharmacist on optimising the quality use of medicines according to the acute coronary syndrome (ACS) secondary prevention guidelines and medication adherence following discharge in patients with ACS in Sri Lanka: a prospective non-randomised controlled trial study protocol by Bagyawantha, Nanayakkara Muhandiramalaya Yasakalum, Coombes, Ian D, Gawarammana, Indika, Fahim, Mohamed

“…ObjectivesEnsuring quality use of medicines (QUM) through clinical pharmacy services can improve therapeutic outcomes of patients diagnosed with acute coronary…”
Get full text

Multifaceted pharmacist-led interventions in secondary care settings between countries of various income levels: a scoping review protocol by Tharmalinga Sharma, Jegath Janani, McMillan, Sara S, Samaranayake, Nithushi R, Waas, Dulshika A, Coombes, Ian D, Wheeler, Amanda J

“…IntroductionClinical pharmacy services often involve multifaceted pharmacist-led interventions. However, current pharmacy practice models vary across different…”
Get full text

Impact of the change from the seventh to eighth edition of the AJCC TNM classification of malignant tumours and comparison with the MACIS prognostic scoring system in non‐medullary thyroid cancer by Dwamena, S., Patel, N., Egan, R., Stechman, M., Scott‐Coombes, D.

“…Background In 2018, AJCC TNM staging changed for differentiated (DTC) and anaplastic (ATC) thyroid carcinoma. The impact of this change on mortality rates was…”
Get full text

Osteopontin Promotes Cholangiocyte Secretion of Chemokines to Support Macrophage Recruitment and Fibrosis in MASH by Coombes, Jason D, Manka, Paul P, Swiderska-Syn, Marzena, Vannan, Danielle T, Riva, Antonio, Claridge, Lee C, Moylan, Cynthia, Suzuki, Ayako, Briones-Orta, Marco A, Younis, Rasha, Kitamura, Naoto, Sydor, Svenja, Bittencourt, Shanna, Mi, Zhiyong, Kuo, Paul C, Diehl, Anna Mae, van Grunsven, Leo A, Chokshi, Shilpa, Canbay, Ali, Abdelmalek, Manal F, Aspichueta, Patricia, Papa, Salvatore, Eksteen, Bertus, Syn, Wing-Kin

“…Osteopontin (OPN) promotes the ductular reaction and is a major driver of chronic liver disease (CLD) progression. Although CLD is characterised by the…”
Get full text

Day case surgery for single jaw orthognathic procedures: a survey of united kingdom-based practice by Shastri, M, Law, C, Coombes, D

Get full text

Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis by Coombes, Jason D., Choi, Steve S., Swiderska-Syn, Marzena, Manka, Paul, Reid, Danielle T., Palma, Elena, Briones-Orta, Marco A., Xie, Guanhua, Younis, Rasha, Kitamura, Naoto, della Peruta, Marco, Bitencourt, Shanna, Dollé, Laurent, Oo, Ye Htun, Mi, Zhiyong, Kuo, Paul C., Williams, Roger, Chokshi, Shilpa, Canbay, Ali, Claridge, Lee C., Eksteen, Bertus, Diehl, Anna Mae, Syn, Wing-Kin

“…Liver fibrosis develops when hepatic stellate cells (HSC) are activated into collagen-producing myofibroblasts. In non-alcoholic steatohepatitis (NASH), the…”
Get full text

Effect of intraoperative nerve monitoring on postoperative vocal cord palsy rates after thyroidectomy: European multicentre registry‐based study by Staubitz, J. I., Watzka, F., Poplawski, A., Riss, P., Clerici, T., Bergenfelz, A., Musholt, T. J., Riss, P., Slycke, S., Iacobone, M., Brunaud, L., Bergenfelz, A., Clerici, T., Villar, J., Raffaelli, M., Scott‐Coombes, D.

“…Background Intraoperative nerve monitoring (IONM) of the recurrent laryngeal nerve (RLN) predicts the risk of vocal cord palsy (VCP). IONM can be used to adapt…”
Get full text

Why do interns make prescribing errors? A qualitative study by Coombes, Ian D, Stowasser, Danielle A, Coombes, Judith A, Mitchell, Charles

“…Objective: To identify and analyse factors underlying intern prescribing errors to inform development of specific medication‐safety interventions. Design: A…”
Get full text

Nasal reconstruction: a brief history, current techniques and advances by Watson, L, Mohamedbhai, H, Dubb, S, Uzoho, C, Coombes, D

Get full text

Hypocalcaemia and Parathyroid Hormone Assay Following Total Thyroidectomy: Predicting the Future by Wong, C., Price, S., Scott‐Coombes, D.

“…Background Ambulatory surgery (23:59‐hour hospital stay) is gaining popularity in endocrine surgery. Hypocalcaemia is common following total thyroidectomy…”
Get full text

Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis by Rangan, Gopala K., Coombes, Jason D.

“…Background. In this study we tested the hypothesis that sirolimus (a target of rapamycin inhibitor that attenuates intrinsic renal and immune cell…”
Get full text

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19 by Coombes, Ian D, Dooley, Michael J, Townsend, Shane, Carmichael, Sinead, Poole, Susan G, Karamujic, Nermin, Richards, Brent, Ziegenfuss, Marc, Ankravs, Melissa J, Uren, Hailie, Roberts, Jason A, Holley, Anthony

“…The coronavirus disease 2019 (COVID-19) pandemic has overwhelmed many international health care systems, with a high number of patients having severe…”
Get full text