Search Results - "Coomans, Claudia P"

Detrimental effects of constant light exposure and high‐fat diet on circadian energy metabolism and insulin sensitivity by Coomans, Claudia P., Berg, Sjoerd A. A., Houben, Thijs, Klinken, Jan‐Bert, Berg, Rosa, Pronk, Amanda C. M., Havekes, Louis M., Romijn, Johannes A., Dijk, Ko Willems, Biermasz, Nienke R., Meijer, Johanna H.

“…Circadian rhythm disturbances are observed in, e.g., aging and neurodegenerative diseases and are associated with an increased incidence of obesity and…”
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Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity by Kooijman, Sander, van den Berg, Rosa, Ramkisoensing, Ashna, Boon, Mariëtte R., Kuipers, Eline N., Loef, Marieke, Zonneveld, Tom C. M., Lucassen, Eliane A., Sips, Hetty C. M., Chatzispyrou, Iliana A., Houtkooper, Riekelt H., Meijer, Johanna H., Coomans, Claudia P., Biermasz, Nienke R., Rensen, Patrick C. N.

“…Disruption of circadian rhythmicity is associated with obesity and related disorders, including type 2 diabetes and cardiovascular disease. Specifically,…”
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Regulation of circadian and acute activity levels by the murine suprachiasmatic nuclei by Houben, Thijs, Coomans, Claudia P, Meijer, Johanna H

“…The suprachiasmatic nuclei (SCN) coordinate the daily sleep-wake cycle by generating a circadian rhythm in electrical impulse frequency. While period and phase…”
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The Suprachiasmatic Nucleus Controls Circadian Energy Metabolism and Hepatic Insulin Sensitivity by COOMANS, Claudia P, VAN DEN BERG, Sjoerd A. A, MEIJER, Johanna H, LUCASSEN, Eliane A, HOUBEN, Thijs, PRONK, Amanda C. M, VAN DER SPEK, Rianne D, KALSBEEK, Andries, BIERMASZ, Nienke R, VAN DIJK, Ko Willems, ROMIJN, Johannes A

“…Disturbances in the circadian system are associated with the development of type 2 diabetes mellitus. Here, we studied the direct contribution of the…”
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Doublecortin-like knockdown in mice attenuates obesity by stimulating energy expenditure in adipose tissue by Modder, Melanie, Coomans, Claudia P., Saaltink, Dirk-Jan, Tersteeg, Mayke M. H., Hoogduin, Janna, Scholten, Leonie, Pronk, Amanda C. M., Lalai, Reshma A., Boelen, Anita, Kalsbeek, Andries, Rensen, Patrick C. N., Vreugdenhil, Erno, Kooijman, Sander

“…Crosstalk between peripheral metabolic organs and the central nervous system is essential for body weight control. At the base of the hypothalamus, β-tanycytes…”
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Lack of exercise leads to significant and reversible loss of scale invariance in both aged and young mice by Gu, Changgui, Coomans, Claudia P., Hu, Kun, Scheer, Frank A. J. L., Stanley, H. Eugene, Meijer, Johanna H.

“…Significance Healthy systems are characterized by scale invariance across multiple timescales. We investigated whether loss of scale invariance that occurs…”
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Thyroid Hormone Effects on Whole-Body Energy Homeostasis and Tissue-Specific Fatty Acid Uptake in Vivo by Klieverik, Lars P, Coomans, Claudia P, Endert, Erik, Sauerwein, Hans P, Havekes, Louis M, Voshol, Peter J, Rensen, Patrick C. N, Romijn, Johannes A, Kalsbeek, Andries, Fliers, Eric

“…The effects of thyroid hormone (TH) status on energy metabolism and tissue-specific substrate supply in vivo are incompletely understood. To study the effects…”
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Group housing and social dominance hierarchy affect circadian activity patterns in mice by Robbers, Yuri, Tersteeg, Mayke M H, Meijer, Johanna H, Coomans, Claudia P

“…In this study, we investigated the effect of social environment on circadian patterns in activity by group housing either six male or six female mice together…”
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Environmental 24-hr Cycles Are Essential for Health by Lucassen, Eliane A., Coomans, Claudia P., van Putten, Maaike, de Kreij, Suzanne R., van Genugten, Jasper H.L.T., Sutorius, Robbert P.M., de Rooij, Karien E., van der Velde, Martijn, Verhoeve, Sanne L., Smit, Jan W.A., Löwik, Clemens W.G.M., Smits, Hermelijn H., Guigas, Bruno, Aartsma-Rus, Annemieke M., Meijer, Johanna H.

“…Circadian rhythms are deeply rooted in the biology of virtually all organisms. The pervasive use of artificial lighting in modern society disrupts circadian…”
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The suprachiasmatic nuclei as a seasonal clock by Coomans, Claudia P, Ramkisoensing, Ashna, Meijer, Johanna H

“…Highlights • The ability of the SCN to encode seasonal information is a network property. • Their unique response to light enables SCN neurons to measure day…”
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Stimulatory Effect of Insulin on Glucose Uptake by Muscle Involves the Central Nervous System in Insulin-Sensitive Mice by COOMANS, Claudia P, BIERMASZ, Nienke R, GEERLING, Janine J, GUIGAS, Bruno, RENSEN, Patrick C. N, HAVEKES, Louis M, ROMIJN, Johannes A

“…Insulin inhibits endogenous glucose production (EGP) and stimulates glucose uptake in peripheral tissues. Hypothalamic insulin signaling is required for the…”
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Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix by Berbée, Jimmy F.P., Coomans, Claudia P., Westerterp, Marit, Romijn, Johannes A., Havekes, Louis M., Rensen, Patrick C.N.

“…Timely sensing of lipopolysaccharide (LPS) is critical for the host to fight invading Gram-negative bacteria. We recently showed that apolipoprotein CI (apoCI)…”
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The role of the circadian system in the etiology of depression by de Leeuw, Max, Verhoeve, Sanne I., van der Wee, Nic J.A., van Hemert, Albert M., Vreugdenhil, Erno, Coomans, Claudia P.

“…Circadian rhythms have evolved in almost all organisms enabling them to anticipate alternating changes in the environment. As a consequence, the circadian…”
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Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice by Coomans, Claudia P., Geerling, Janine J., Guigas, Bruno, van den Hoek, Anita M., Parlevliet, Edwin T., Ouwens, D. Margriet, Pijl, Hanno, Voshol, Peter J., Rensen, Patrick C.N., Havekes, Louis M., Romijn, Johannes A.

“…Insulin signaling in the central nervous system (CNS) is required for the inhibitory effect of insulin on glucose production. Our aim was to determine whether…”
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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening by van den Berg, Rosa, Kooijman, Sander, Noordam, Raymond, Ramkisoensing, Ashna, Abreu-Vieira, Gustavo, Tambyrajah, Lauren L., Dijk, Wieneke, Ruppert, Philip, Mol, Isabel M., Kramar, Barbara, Caputo, Rosanna, Puig, Laura Sardón, de Ruiter, Evelien M., Kroon, Jan, Hoekstra, Menno, van der Sluis, Ronald J., Meijer, Onno C., Willems van Dijk, Ko, van Kerkhof, Linda W.M., Christodoulides, Constantinos, Karpe, Fredrik, Gerhart-Hines, Zachary, Kersten, Sander, Meijer, Johanna H., Coomans, Claudia P., van Heemst, Diana, Biermasz, Nienke R., Rensen, Patrick C.N.

“…Many favorable metabolic effects have been attributed to thermogenic activity of brown adipose tissue (BAT). Yet, time of day has rarely been considered in…”
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USF1 deficiency activates brown adipose tissue and improves cardiometabolic health by Laurila, Pirkka-Pekka, Soronen, Jarkko, Kooijman, Sander, Forsström, Saara, Boon, Mariëtte R, Surakka, Ida, Kaiharju, Essi, Coomans, Claudia P, Van Den Berg, Sjoerd A A, Autio, Anu, Sarin, Antti-Pekka, Kettunen, Johannes, Tikkanen, Emmi, Manninen, Tuula, Metso, Jari, Silvennoinen, Reija, Merikanto, Krista, Ruuth, Maija, Perttilä, Julia, Mäkelä, Anne, Isomi, Ayaka, Tuomainen, Anita M, Tikka, Anna, Ramadan, Usama Abo, Seppälä, Ilkka, Lehtimäki, Terho, Eriksson, Johan, Havulinna, Aki, Jula, Antti, Karhunen, Pekka J, Salomaa, Veikko, Perola, Markus, Ehnholm, Christian, Lee-Rueckert, Miriam, Van Eck, Miranda, Roivainen, Anne, Taskinen, Marja-Riitta, Peltonen, Leena, Mervaala, Eero, Jalanko, Anu, Hohtola, Esa, Olkkonen, Vesa M, Ripatti, Samuli, Kovanen, Petri T, Rensen, Patrick C N, Suomalainen, Anu, Jauhiainen, Matti

“…USF1 (upstream stimulatory factor 1) is a transcription factor associated with familial combined hyperlipidemia and coronary artery disease in humans. However,…”
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Continuous Light Does Not Affect Atherosclerosis in APOE3-Leiden.CETP Mice by Schilperoort, Maaike, van den Berg, Rosa, Coomans, Claudia P., Khedoe, Padmini P. S. J., Ramkisoensing, Ashna, Boekestijn, Sanne, Wang, Yanan, Berbée, Jimmy F. P., Meijer, Johanna H., Biermasz, Nienke R., Rensen, Patrick C. N., Kooijman, Sander

“…Artificial light exposure is associated with dyslipidemia in humans, which is a major risk factor for the development of atherosclerotic cardiovascular…”
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Glucocorticoid excess induces long‐lasting changes in body composition in male C57Bl/6J mice only with high‐fat diet by Auvinen, Hanna E., Coomans, Claudia P., Boon, Mariëtte R., Romijn, Johannes A., Biermasz, Nienke R., Meijer, Onno C., Havekes, Louis M., Smit, Johannes W. A., Rensen, Patrick C. N., Pereira, Alberto M.

“…Glucocorticoid (GC) overexposure period as observed in Cushing's syndrome (CS) is associated with the metabolic syndrome and cardiovascular disease, which…”
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The brain modulates insulin sensitivity in multiple tissues by Parlevliet, Edwin T, Coomans, Claudia P, Rensen, Patrick C N, Romijn, Johannes A

“…Insulin sensitivity is determined by direct effects of circulating insulin on metabolically active tissues in combination with indirect effects of circulating…”
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Abstract 224: Biological Clock Strongly Regulates Brown Adipose Tissue Activity: Implications for Postprandial Triglyceride Metabolism by Berbée, Jimmy, van den Berg, Rosa, Kooijman, Sander, Ramkisoensing, Ashna, Coomans, Claudia P, Meijer, Johanna H, Biermasz, Nienke R, Rensen, Patrick C

“…Abstract only Background: Brown adipose tissue (BAT) is an attractive anti-dyslipidemia target as it burns high amounts of triglycerides (TG) into heat. In…”
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