Search Results - "Coolen, Lique M"

Minireview: Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cells of the Arcuate Nucleus: A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion by Lehman, Michael N, Coolen, Lique M, Goodman, Robert L

“…Recently, a subset of neurons was identified in the arcuate nucleus of the hypothalamus that colocalize three neuropeptides, kisspeptin, neurokinin B, and…”
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In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse by Moore, Aleisha M, Coolen, Lique M, Lehman, Michael N

“…A hypothalamic pulse generator located in the arcuate nucleus controls episodic release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH)…”
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Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice by Moore, Aleisha M., Coolen, Lique M., Lehman, Michael N.

“…Neurons in the hypothalamic arcuate nucleus (ARC) that co-express kisspeptin, neurokinin B and dynorphin (KNDy cells) are essential for mammalian reproduction…”
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The Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cell Population of the Arcuate Nucleus: Sex Differences and Effects of Prenatal Testosterone in Sheep by Cheng, Guanliang, Coolen, Lique M, Padmanabhan, Vasantha, Goodman, Robert L, Lehman, Michael N

“…Recent work in sheep has identified a neuronal subpopulation in the arcuate nucleus that coexpresses kisspeptin, neurokinin B, and dynorphin (referred to here…”
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Highlights of neuroanatomical discoveries of the mammalian gonadotropin‐releasing hormone system by Campbell, Rebecca E., Coolen, Lique M., Hoffman, Gloria E., Hrabovszky, Erik

“…The anatomy and morphology of gonadotropin‐releasing hormone (GnRH) neurons makes them both a joy and a challenge to investigate. They are a highly unique…”
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Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes by Goodman, Robert L, Hileman, Stanley M, Nestor, Casey C, Porter, Katrina L, Connors, John M, Hardy, Steve L, Millar, Robert P, Cernea, Maria, Coolen, Lique M, Lehman, Michael N

“…Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy) neurons in the arcuate nucleus play a key role in GnRH pulse generation,…”
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Anatomy of the kisspeptin neural network in mammals by Lehman, Michael N, Merkley, Christina M, Coolen, Lique M, Goodman, Robert L

“…Abstract Kisspeptin has been recognized as a key regulator of GnRH secretion during puberty and adulthood, conveying the feedback influence of endogenous…”
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Regulation of GnRH pulsatility in ewes by Nestor, Casey C, Bedenbaugh, Michelle N, Hileman, Stanley M, Coolen, Lique M, Lehman, Michael N, Goodman, Robert L

“…Early work in ewes provided a wealth of information on the physiological regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion by internal…”
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Activation of mu or delta opioid receptors in the lumbosacral spinal cord is essential for ejaculatory reflexes in male rats by Kozyrev, Natalie, Coolen, Lique M

“…Ejaculation is controlled by a spinal ejaculation generator located in the lumbosacral spinal cord, consisting in male rats of lumbar spinothalamic (LSt) cells…”
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KNDy (Kisspeptin/Neurokinin B/Dynorphin) Neurons Are Activated during Both Pulsatile and Surge Secretion of LH in the Ewe by Merkley, Christina M, Porter, Katrina L, Coolen, Lique M, Hileman, Stanley M, Billings, Heather J, Drews, Sara, Goodman, Robert L, Lehman, Michael N

“…KNDy (kisspeptin/neurokinin B/dynorphin) neurons of the arcuate nucleus (ARC) appear to mediate the negative feedback actions of estradiol and are thought to…”
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Molecular Mapping of the Neural Pathways Linking Leptin to the Neuroendocrine Reproductive Axis by Louis, Gwendolyn W, Greenwald-Yarnell, Megan, Phillips, Rebecca, Coolen, Lique M, Lehman, Michael N, Myers, Martin G

“…Leptin communicates with the neuroendocrine reproductive axis via multiple populations of LepRb neurons that lie afferent to both Kiss1 and GnRH neurons…”
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A role for neurokinin B in pulsatile GnRH secretion in the ewe by Goodman, Robert L, Coolen, Lique M, Lehman, Michael N

“…The recent description of infertility in humans with loss-of-function mutations in genes for neurokinin B (NKB) or its receptor (NK3R) has focused attention on…”
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Variation in Kisspeptin and RFamide-Related Peptide (RFRP) Expression and Terminal Connections to Gonadotropin-Releasing Hormone Neurons in the Brain: A Novel Medium for Seasonal Breeding in the Sheep by Smith, Jeremy T, Coolen, Lique M, Kriegsfeld, Lance J, Sari, Ika P, Jaafarzadehshirazi, Mohammad R, Maltby, Matthew, Bateman, Katherine, Goodman, Robert L, Tilbrook, Alan J, Ubuka, Takayoshi, Bentley, George E, Clarke, Iain J, Lehman, Michael N

“…Reproductive activity in sheep is seasonal, being activated by short-day photoperiods and inhibited by long days. During the nonbreeding season, GnRH secretion…”
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Kisspeptin Neurons in the Arcuate Nucleus of the Ewe Express Both Dynorphin A and Neurokinin B by Goodman, Robert L, Lehman, Michael N, Smith, Jeremy T, Coolen, Lique M, de Oliveira, Cleusa V. R, Jafarzadehshirazi, Mohammad R, Pereira, Alda, Iqbal, Javed, Caraty, Alain, Ciofi, Philippe, Clarke, Iain J

“…Kisspeptin is a potent stimulator of GnRH secretion that has been implicated in the feedback actions of ovarian steroids. In ewes, the majority of hypothalamic…”
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Does the KNDy Model for the Control of Gonadotropin-Releasing Hormone Pulses Apply to Monkeys and Humans? by Lehman, Michael N, He, Wen, Coolen, Lique M, Levine, Jon E, Goodman, Robert L

“…There is now considerable evidence supporting the role of a subpopulation of neurons in the arcuate nucleus of the hypothalamus that coexpress kisspeptin,…”
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Ventral Tegmental Area Dopamine Cell Activation during Male Rat Sexual Behavior Regulates Neuroplasticity and d-Amphetamine Cross-Sensitization following Sex Abstinence by Beloate, Lauren N, Omrani, Azar, Adan, Roger A, Webb, Ian C, Coolen, Lique M

“…Experience with sexual behavior causes cross-sensitization of amphetamine reward, an effect dependent on a period of sexual reward abstinence. We previously…”
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20-HETE Enzymes and Receptors in the Neurovascular Unit: Implications in Cerebrovascular Disease by Gonzalez-Fernandez, Ezekiel, Staursky, Daniel, Lucas, Kathryn, Nguyen, Bond V, Li, Man, Liu, Yedan, Washington, Chad, Coolen, Lique M, Fan, Fan, Roman, Richard J

“…20-HETE is a potent vasoconstrictor that is implicated in the regulation of blood pressure, cerebral blood flow and neuronal death following ischemia. Numerous…”
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Spinal Cord Injury Causes Reduction of Galanin and Gastrin Releasing Peptide mRNA Expression in the Spinal Ejaculation Generator of Male Rats by Wiggins, James W., Sledd, Jonathan E., Coolen, Lique M.

“…Spinal cord injury (SCI) in men is commonly associated with sexual dysfunction, including anejaculation, and chronic mid-thoracic contusion injury in male rats…”
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Chronic Spinal Cord Injury Reduces Gastrin-Releasing Peptide in the Spinal Ejaculation Generator in Male Rats by Wiggins, J Walker, Kozyrev, Natalie, Sledd, Jonathan E, Wilson, George G, Coolen, Lique M

“…Spinal cord injury (SCI) causes sexual dysfunction, including anejaculation in men. Likewise, chronic mid-thoracic contusion injury impairs ejaculatory…”
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Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice by Jamieson, Bradley B, Moore, Aleisha M, Lohr, Dayanara B, Thomas, Simone X, Coolen, Lique M, Lehman, Michael N, Campbell, Rebecca E, Piet, Richard

“…Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. Evidence indicates…”
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