Search Results - "Cooke, Jason"

Oscillatory Properties of Functional Connections Between Sensory Areas Mediate Cross-Modal Illusory Perception by Cooke, Jason, Poch, Claudia, Gillmeister, Helge, Costantini, Marcello, Romei, Vincenzo

“…The presentation of simple auditory stimuli can significantly impact visual processing and even induce visual illusions, such as the auditory-induced double…”
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Assessing the specificity of the relationship between brain alpha oscillations and tonic pain by Valentini, Elia, Halder, Sebastian, McInnerney, Daisy, Cooke, Jason, Gyimes, Istvan L., Romei, Vincenzo

“…Recent research proposed that the slowing of individual alpha frequency (IAF) could be an objective marker of pain. However, it is unclear whether this…”
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Rolling Contact Fatigue Life and Spall Propagation of AISI M50, M50NiL, and AISI 52100, Part I: Experimental Results by Rosado, Lewis, Forster, Nelson H., Thompson, Kevin L., Cooke, Jason W.

“…This article is the first part of a three-part series that investigates the rolling contact fatigue (RCF) initiation and spall propagation characteristics of…”
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Optimization of the Preparation of (R)‑3,5-Bis(trifluoromethyl)-α-methyl‑N‑methylbenzylamine l‑(−)-Malic Acid Salt through Classical Resolution by Brandel, Clément M, Cooke, Jason W. B, Horan, Richard A. J, Mallet, Franck P, Stevens, David R

“…An improved process for the manufacture of (R)-3,5-bis­(trifluoromethyl)-α-methyl-N-methylbenzylamine l-(−)-malic acid salt (1), a key starting material for…”
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Live 3D Echocardiography: A Replacement for Traditional 2D Echocardiography? by Houck, Robin C, Cooke, Jason E, Gill, Edward A

“…We describe the development of real-time 3D imaging and review the previously used versions of 3D echocardiography so that the reader will appreciate why…”
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The Fit For Purpose Development of S1P1 Receptor Agonist GSK2263167 Using a Robinson Annulation and Saegusa Oxidation to Access an Advanced Phenol Intermediate by Harris, Robert M, Andrews, Benjamin I, Clark, Stacy, Cooke, Jason W. B, Gray, John C. S, Ng, Stephanie Q. Q

“…A fit for purpose approach has been adopted in order to develop a robust, scalable route to the S1P1 receptor agonist, GSK2263167. The key steps include a…”
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Asymmetric synthesis of beta-amino-gamma-substituted-gamma-butyrolactones: double diastereoselective conjugate addition of homochiral lithium amides to homochiral alpha,beta-unsaturated esters by Cailleau, Thaïs, Cooke, Jason W B, Davies, Stephen G, Ling, Kenneth B, Naylor, Alan, Nicholson, Rebecca L, Price, Paul D, Roberts, Paul M, Russell, Angela J, Smith, Andrew D, Thomson, James E

“…Chiral alpha,beta-unsaturated esters, containing a single, gamma-stereogenic centre, show modest levels of substrate control upon conjugate addition of lithium…”
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Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate by Demont, Emmanuel H, Andrews, Benjamin I, Bit, Rino A, Campbell, Colin A, Cooke, Jason W. B, Deeks, Nigel, Desai, Sapna, Dowell, Simon J, Gaskin, Pam, Gray, James R. J, Haynes, Andrea, Holmes, Duncan S, Kumar, Umesh, Morse, Mary A, Osborne, Greg J, Panchal, Terry, Patel, Bela, Perboni, Alcide, Taylor, Simon, Watson, Robert, Witherington, Jason, Willis, Robert

“…Gilenya (fingolimod, FTY720) was recently approved by the U.S. FDA for the treatment of patients with remitting relapsing multiple sclerosis (RRMS). It is a…”
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Effect of rhPDGF-BB on bone turnover during periodontal repair by Sarment, David P., Cooke, Jason W., Miller, Sarah E., Jin, Qiming, McGuire, Michael K., Kao, Richard T., McClain, Pamela K., McAllister, Bradley S., Lynch, Samuel E., Giannobile, William V.

“…Purpose: Growth factors such as platelet‐derived growth factor (PDGF) exert potent effects on wound healing including the regeneration of periodontia…”
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Syntheses of Four-Coordinate Nickel(II)-Phosphine Compounds and a Rapid Suzuki–Miyaura Cross-Coupling Reaction for Short Laboratory Sessions by Cooke, Jason

“…[NiBr2(PPh3)2] and [NiBr2(dppe)] are prepared from nickel bromide hydrate and phosphine. These brightly colored coordination compounds are then converted into…”
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Development of an Efficient Large-Scale Synthesis for a 4 H -imidazo[5,1- c ][1,4]benzoxazine-3-carboxamide Derivative for Depression and Anxiety by Giubellina, Nicola, Stabile, Paolo, Laval, Gilles, Perboni, Alcide D., Cimarosti, Zadeo, Westerduin, Pieter, Cooke, Jason W. B.

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Development of an Efficient Large-Scale Synthesis for a 4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide Derivative for Depression and Anxiety by Giubellina, Nicola, Stabile, Paolo, Laval, Gilles, Perboni, Alcide D, Cimarosti, Zadeo, Westerduin, Pieter, Cooke, Jason W. B

“…The development and scale-up of an optimized synthesis for a novel drug candidate for depression and anxiety is presented. The updated synthesis represents a…”
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Savagery Repositioned: Historicizing the Cherokee Nation by Cooke, Jason

“…Americanist scholarship often portrays historicization during Cherokee removal in terms of a single Indian-Anglo binary, with images of anachronistic savagery…”
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Asymmetric synthesis of 4-amino-γ-butyrolactones via lithium amide conjugate addition by Abraham, Elin, Cooke, Jason W.B., Davies, Stephen G., Naylor, Alan, Nicholson, Rebecca L., Price, Paul. D., Smith, Andrew D.

“…Upon treatment with homochiral lithium ( R)- N-benzyl- N-(α-methylbenzyl)amide, γ-benzyloxy but-2-enoates undergo competitive conjugate addition and…”
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Route Selection and Process Development for a 5-Piperazinylquinaldine Derivative for the Treatment of Depression and Anxiety by Cimarosti, Zadeo, Giubellina, Nicola, Stabile, Paolo, Laval, Gilles, Tinazzi, Francesco, Maton, William, Pachera, Roberta, Russo, Paola, Moretti, Ramona, Rossi, Sara, Cooke, Jason W. B., Westerduin, Pieter

“…1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone, 1, was identified as a potential drug for the treatment of depression and…”
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Process Research and Development of a Dihydropyrimidine Dehydrogenase Inactivator:  Large-Scale Preparation of Eniluracil Using a Sonogashira Coupling by Cooke, Jason W. B, Bright, Robert, Coleman, Mark J, Jenkins, Kevin P

“…Eniluracil (5-ethynyluracil) is a potent inactivator of the enzyme dihydropyrimidine dehydrogenase, which is the rate-limiting enzyme in the metabolism of…”
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Effect of rhPDGF-BB delivery on mediators of periodontal wound repair by Cooke, Jason W, Sarment, David P, Whitesman, Louis A, Miller, Sarah E, Jin, Qiming, Lynch, Samuel E, Giannobile, William V

“…Growth factors such as platelet-derived growth factor (PDGF) exert potent effects on wound healing including the regeneration of tooth-supporting structures…”
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Energy landscape: Los Angeles Harbor and the establishment of oil-based capitalism in Southern California, 1871-1930 by Cooke, Jason

“…In the first three decades of the twentieth century, the Los Angeles metropolitan area emerged as the fastest growing urban-industrial economy on the Pacific…”
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Higher proneness to multisensory illusions is driven by reduced temporal sensitivity in people with high schizotypal traits by Ferri, Francesca, Venskus, Agnese, Fotia, Francesca, Cooke, Jason, Romei, Vincenzo

“…•High-schizotypy was associated with higher proneness to multisensory illusions.•High-schizotypy showed reduced temporal sensitivity relative to…”
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Improved Yields of Dichlorobis(triphenylphosphine)nickel(II) and Related Compounds by Employing Triethyl Orthoformate as an In Situ Dehydrating Agent: Rational Improvement of a Classic Undergraduate Inorganic Synthesis by Hilts, Adrian R., Cooke, Jason

“…The addition of a small excess of triethyl orthoformate to an alcoholic mixture of NiCl2·6H2O and triphenylphosphine (PPh3) results in an increase in the…”
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