Search Results - "Cooke, Darren"

Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine by MARCZYLO, Timothy H, VERSCHOYLE, Richard D, COOKE, Darren N, MORAZZONI, Paolo, STEWARD, William P, GESCHER, Andreas J

“…Curcumin, a major constituent of the spice turmeric, suppresses expression of the enzyme cyclooxygenase 2 (Cox-2) and has cancer chemopreventive properties in…”
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Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance by SHARMA, Ricky A, EUDEN, Stephanie A, PIRMOHAMED, Munir, GESCHER, Andreas J, STEWARD, William P, PLATTON, Sharon L, COOKE, Darren N, SHAFAYAT, Aisha, HEWITT, Heather R, MARCZYLO, Timothy H, MORGAN, Bruno, HEMINGWAY, David, PLUMMER, Simon M

“…Curcumin, a polyphenolic antioxidant derived from a dietary spice, exhibits anticancer activity in rodents and in humans. Its efficacy appears to be related to…”
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Effect of gum tragacanth on the rheological and functional properties of full-fat and half-fat Cheddar cheese by Cooke, Darren R., Khosrowshahi, Asghar, McSweeney, Paul L. H.

“…Fat replacers can be used to improve the sensory and functional properties of reduced-fat cheeses. The effect of gum tragacanth (GT) on the rheological,…”
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Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice by Marczylo, Timothy H, Cooke, Darren, Brown, Karen, Steward, William P, Gescher, Andreas J

“…Purpose Cyanidin-3-glucoside (C3G), an anthocyanin component of fruits and berries, possesses cancer chemopreventive properties in mouse models of…”
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influence of alkaline earth metal equilibria on the rheological properties of rennet-induced skim milk gels by Cooke, Darren R, McSweeney, Paul L. H

“…The mineral equilibria of milk can have a major influence on the properties of rennet milk gels. The influence of increased Mg, Ca, and Sr concentrations on…”
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The influence of alkaline earth metal equilibria on the rheological, melting and textural properties of Cheddar cheese by Cooke, Darren R, McSweeney, Paul L H

“…The total calcium content of cheese, along with changes in the equilibrium between soluble and casein (CN)-bound calcium during ripening can have a major…”
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Breast Cancer Prevention by Green Tea Catechins and Black Tea Theaflavins in the C3(1) SV40 T,t Antigen Transgenic Mouse Model Is Accompanied by Increased Apoptosis and a Decrease in Oxidative DNA Adducts by Kaur, Siminder, Greaves, Peter, Cooke, Darren N, Edwards, Richard, Steward, William P, Gescher, Andreas J, Marczylo, Timothy H

“…Tea consumption is associated with a reduced risk of mammary cancer as reflected by epidemiological studies and experiments in carcinogen-induced rodent models…”
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Development of Analyses by High-Performance Liquid Chromatography and Liquid Chromatography/Tandem Mass Spectrometry of Bilberry (Vaccinium myrtilus) Anthocyanins in Human Plasma and Urine by Cooke, Darren N, Thomasset, Sarah, Boocock, David J, Schwarz, Michael, Winterhalter, Peter, Steward, William P, Gescher, Andreas J, Marczylo, Timothy H

“…Anthocyanins are potent antioxidants that may possess chronic disease preventive properties. Here, rapid, reliable, and reproducible solid-phase extraction,…”
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Anthocyans from fruits and vegetables – Does bright colour signal cancer chemopreventive activity? by Cooke, Darren, Steward, William P., Gescher, Andreas J., Marczylo, Tim

“…Consumption of fruits and berries has been associated with decreased risk of developing cancer. The most abundant flavonoid constituents of fruits and berries…”
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Phase I Clinical Trial of Oral Curcumin by Sharma, Ricky A., Euden, Stephanie A., Platton, Sharon L., Cooke, Darren N., Shafayat, Aisha, Hewitt, Heather R., Marczylo, Timothy H., Morgan, Bruno, Hemingway, David, Plummer, Simon M., Pirmohamed, Munir, Gescher, Andreas J., Steward, William P.

“…Curcumin, a polyphenolic antioxidant derived from a dietary spice, exhibits anticancer activity in rodents and in humans. Its efficacy appears to be related to…”
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Anthocyans from fruits and vegetables : Does bright colour signal cancer chemopreventive activity?: Cancer chemoprevention - An update on a novel and exciting field of oncology by COOKE, Darren, STEWARD, William P, GESCHER, Andreas J, MARCZYLO, Tim

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Pre-clinical development of anthocyanins as colorectal cancer chemopreventive agents by Cooke, Darren

“…The hypothesis was tested that dietary Mirtoselect, a standardised mixture of 15 anthocyanins, or the isolated anthocyanin cyanidin-3-glucoside (C3G) affect…”
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Effect of cyanidin-3-glucoside and an anthocyanin mixture from bilberry on adenoma development in the Apc super(Min) mouse model of intestinal carcinogenesis-Relationship with tissue anthocyanin levels by Cooke, Darren, Schwarz, Michael, Boocock, David, Winterhalter, Peter, Steward, William P, Gescher, Andreas J, Marczylo, Timothy H

“…Anthocyanins are dietary flavonoids, which can prevent carcinogen-induced colorectal cancer in rats. Here, the hypotheses were tested that Mirtoselect, an…”
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Effect of cyanidin‐3‐glucoside and an anthocyanin mixture from bilberry on adenoma development in the Apc Min mouse model of intestinal carcinogenesis—Relationship with tissue anthocyanin levels by Cooke, Darren, Schwarz, Michael, Boocock, David, Winterhalter, Peter, Steward, William P., Gescher, Andreas J., Marczylo, Timothy H.

“…Abstract Anthocyanins are dietary flavonoids, which can prevent carcinogen‐induced colorectal cancer in rats. Here, the hypotheses were tested that…”
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Effect of cyanidin‐3‐glucoside and an anthocyanin mixture from bilberry on adenoma development in the ApcMin mouse model of intestinal carcinogenesis—Relationship with tissue anthocyanin levels by Cooke, Darren, Schwarz, Michael, Boocock, David, Winterhalter, Peter, Steward, William P., Gescher, Andreas J., Marczylo, Timothy H.

“…Anthocyanins are dietary flavonoids, which can prevent carcinogen‐induced colorectal cancer in rats. Here, the hypotheses were tested that Mirtoselect, an…”
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Implants for cranioplasty by Gladstone, H B, McDermott, M W, Cooke, D D

“…As long as there have been skull defects, there has been a recognized need to cover them in some way. Cranioplasty is the surgical correction of skull defects…”
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Acoustic neuroma surgery : Outcome analysis of patient-perceived disability by RIGBY, P. L, SHAH, S. B, JACKLER, R. K, CHUNG, J. H, COOKE, D. D

“…Numerous studies have investigated the outcome of acoustic neuroma (AN) treatment using classical medical measures. In an effort to describe the long-term…”
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Socioeconomic impact of acoustic neuroma surgery by CHUNG, J. H, RIGBY, P. L, JACKLER, R. K, SHAH, S. B, COOKE, D. D

“…This study aimed to assess the impact of acoustic neuroma (AN) surgery on socioeconomic function. This study was a retrospective postal survey. The study was…”
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