Search Results - "Cook, Nancy"

Use and misuse of the receiver operating characteristic curve in risk prediction by COOK, Nancy R

“…The c statistic, or area under the receiver operating characteristic (ROC) curve, achieved popularity in diagnostic testing, in which the test characteristics…”
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Statistical Evaluation of Prognostic versus Diagnostic Models : Beyond the ROC Curve by COOK, Nancy R

“…Diagnostic and prognostic or predictive models serve different purposes. Whereas diagnostic models are usually used for classification, prognostic models…”
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Statins: new American guidelines for prevention of cardiovascular disease by Ridker, Paul M, Cook, Nancy R

“…4·9 mmol/L [190 mg/dL]) the benefits on heart attack, stroke, and cardiovascular death significantly outweigh the risks for developing diabetes or myopathy…”
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Childhood Blood Pressure Trends and Risk Factors for High Blood Pressure: The NHANES Experience 1988–2008 by Rosner, Bernard, Cook, Nancy R, Daniels, Stephen, Falkner, Bonita

“…The obesity epidemic in children makes it plausible that prevalence rates of elevated blood pressure (BP) are increasing over time. Yet, previous literature is…”
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Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention by Cook, Nancy R., ScD, Appel, Lawrence J., MD, Whelton, Paul K., MD

“…Abstract Background The relationship between lower sodium intake and total mortality remains controversial. Objectives This study examined the relationship…”
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Environmental Chemicals in Urine and Blood: Improving Methods for Creatinine and Lipid Adjustment by O'Brien, Katie M, Upson, Kristen, Cook, Nancy R, Weinberg, Clarice R

“…Investigators measuring exposure biomarkers in urine typically adjust for creatinine to account for dilution-dependent sample variation in urine…”
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Tests of calibration and goodness-of-fit in the survival setting by Demler, Olga V., Paynter, Nina P., Cook, Nancy R.

“…To access the calibration of a predictive model in a survival analysis setting, several authors have extended the Hosmer–Lemeshow goodness‐of‐fit test to…”
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Calibration of the Pooled Cohort Equations for Atherosclerotic Cardiovascular Disease: An Update by Cook, Nancy R, Ridker, Paul M

“…The latest guidelines from the American College of Cardiology and American Heart Association, released in fall 2013, provide a long-anticipated update to the…”
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Triglyceride-Rich Lipoprotein Cholesterol, Small Dense LDL Cholesterol, and Incident Cardiovascular Disease by Duran, Edward K., Aday, Aaron W., Cook, Nancy R., Buring, Julie E., Ridker, Paul M, Pradhan, Aruna D.

“…Elevated triglyceride-rich lipoprotein (TRL) and small-dense low-density lipoprotein (sdLDL) particles are hallmarks of atherogenic dyslipidemia, and their…”
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Lower Levels of Sodium Intake and Reduced Cardiovascular Risk by Cook, Nancy R, Appel, Lawrence J, Whelton, Paul K

“…BACKGROUND—Recent studies have raised the possibility of adverse effects of low sodium, particularly <2300 mg/d, on cardiovascular disease; however, these…”
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Advances in Measuring the Effect of Individual Predictors of Cardiovascular Risk: The Role of Reclassification Measures by COOK, Nancy R, RIDKER, Paul M

“…Models for risk prediction are widely used in clinical practice to stratify risk and assign treatment strategies. The contribution of new biomarkers has…”
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Lipoprotein(a) and Cardiovascular Risk Prediction Among Women by Cook, Nancy R., Mora, Samia, Ridker, Paul M

“…Although lipoprotein(a) [Lp(a)] is associated with incident cardiovascular disease (CVD), its contribution to prediction remains controversial. This study…”
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Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer by Manson, JoAnn E, Cook, Nancy R, Lee, I-Min, Christen, William, Bassuk, Shari S, Mora, Samia, Gibson, Heike, Albert, Christine M, Gordon, David, Copeland, Trisha, D’Agostino, Denise, Friedenberg, Georgina, Ridge, Claire, Bubes, Vadim, Giovannucci, Edward L, Willett, Walter C, Buring, Julie E

“…This article reports the n−3 fatty acid portion of a randomized, placebo-controlled, two-by-two factorial trial of vitamin D and marine n−3 fatty acids in the…”
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Further insight into the cardiovascular risk calculator: the roles of statins, revascularizations, and underascertainment in the Women's Health Study by Cook, Nancy R, Ridker, Paul M

“…While the pooled cohort equations from the recent American College of Cardiology/American Heart Association (ACC/AHA) Guideline on the Assessment of…”
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Sodium and health—concordance and controversy by Cook, Nancy R, He, Feng J, MacGregor, Graham A, Graudal, Niels

“…Nancy Cook and colleagues describe the sources of agreement and disagreement about the health effects of sodium and how they might be resolved…”
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Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial by Hahn, Jill, Cook, Nancy R, Alexander, Erik K, Friedman, Sonia, Walter, Joseph, Bubes, Vadim, Kotler, Gregory, Lee, I-Min, Manson, JoAnn E, Costenbader, Karen H

“…To investigate whether vitamin D and marine derived long chain omega 3 fatty acids reduce autoimmune disease risk. Vitamin D and omega 3 trial (VITAL), a…”
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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease by Khera, Amit V, Emdin, Connor A, Drake, Isabel, Natarajan, Pradeep, Bick, Alexander G, Cook, Nancy R, Chasman, Daniel I, Baber, Usman, Mehran, Roxana, Rader, Daniel J, Fuster, Valentin, Boerwinkle, Eric, Melander, Olle, Orho-Melander, Marju, Ridker, Paul M, Kathiresan, Sekar

“…Using a polygenic score of DNA sequence polymorphisms, the authors of this study quantified genetic risk and assessed four healthy lifestyle factors. Among…”
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Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease by Manson, JoAnn E, Cook, Nancy R, Lee, I-Min, Christen, William, Bassuk, Shari S, Mora, Samia, Gibson, Heike, Gordon, David, Copeland, Trisha, D’Agostino, Denise, Friedenberg, Georgina, Ridge, Claire, Bubes, Vadim, Giovannucci, Edward L, Willett, Walter C, Buring, Julie E

“…This article reports the vitamin D portion of a randomized, two-by-two factorial trial of n−3 fatty acids and vitamin D in the prevention of cancer and…”
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24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk by Ma, Yuan, He, Feng J, Sun, Qi, Yuan, Changzheng, Kieneker, Lyanne M, Curhan, Gary C, MacGregor, Graham A, Bakker, Stephan J.L, Campbell, Norm R.C, Wang, Molin, Rimm, Eric B, Manson, JoAnn E, Willett, Walter C, Hofman, Albert, Gansevoort, Ron T, Cook, Nancy R, Hu, Frank B

“…The relation between sodium intake and cardiovascular disease is controversial. This study used individual-participant data from six prospective cohorts of…”
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Lifestyle and behavioral factors and mitochondrial DNA copy number in a diverse cohort of mid-life and older adults by Vyas, Chirag M, Ogata, Soshiro, Reynolds, Charles F, Mischoulon, David, Chang, Grace, Cook, Nancy R, Manson, JoAnn E, Crous-Bou, Marta, De Vivo, Immaculata, Okereke, Olivia I

“…Mitochondrial DNA copy number (mtDNAcn) is a putative biomarker of oxidative stress and biological aging. Modifiable factors, including physical activity (PA),…”
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