Search Results - "Cook, Malcolm"

SR proteins control a complex network of RNA-processing events by Bradley, Todd, Cook, Malcolm E, Blanchette, Marco

“…SR proteins are a well-conserved class of RNA-binding proteins that are essential for regulation of splice-site selection, and have also been implicated as key…”
Get full text

Paul et Virginie: Embellishing the Text by Cook, Malcolm

“…This article reproduces a recently discovered manuscript in the hand of Bernardin de Saint-Pierre, in which the author gives details about the ways in which he…”
Get full text

Paul et Virginie: Embellishing the Text by Cook, Malcolm

“…This article reproduces a recently discovered manuscript in the hand of Bernardin de Saint-Pierre, in which the author gives details about the ways in which he…”
Get full text

The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution by Smith, Jeramiah J., Timoshevskaya, Nataliya, Ye, Chengxi, Holt, Carson, Keinath, Melissa C., Parker, Hugo J., Cook, Malcolm E., Hess, Jon E., Narum, Shawn R., Lamanna, Francesco, Kaessmann, Henrik, Timoshevskiy, Vladimir A., Waterbury, Courtney K. M., Saraceno, Cody, Wiedemann, Leanne M., Robb, Sofia M. C., Baker, Carl, Eichler, Evan E., Hockman, Dorit, Sauka-Spengler, Tatjana, Yandell, Mark, Krumlauf, Robb, Elgar, Greg, Amemiya, Chris T.

“…The sea lamprey ( Petromyzon marinus ) serves as a comparative model for reconstructing vertebrate evolution. To enable more informed analyses, we developed a…”
Get full text

Hypo-osmotic-like stress underlies general cellular defects of aneuploidy by Tsai, Hung-Ji, Nelliat, Anjali R., Choudhury, Mohammad Ikbal, Kucharavy, Andrei, Bradford, William D., Cook, Malcolm E., Kim, Jisoo, Mair, Devin B., Sun, Sean X., Schatz, Michael C., Li, Rong

“…Aneuploidy, which refers to unbalanced chromosome numbers, represents a class of genetic variation that is associated with cancer, birth defects and eukaryotic…”
Get full text

Quantifying Nucleation In Vivo Reveals the Physical Basis of Prion-like Phase Behavior by Khan, Tarique, Kandola, Tejbir S., Wu, Jianzheng, Venkatesan, Shriram, Ketter, Ellen, Lange, Jeffrey J., Rodríguez Gama, Alejandro, Box, Andrew, Unruh, Jay R., Cook, Malcolm, Halfmann, Randal

“…Protein self-assemblies modulate protein activities over biological timescales that can exceed the lifetimes of the proteins or even the cells that harbor…”
Get full text

The modelling gap: Quantifying the discrepancy in the representation of thermal mass in building simulation by Mantesi, Eirini, Hopfe, Christina J., Cook, Malcolm J., Glass, Jacqueline, Strachan, Paul

“…Enhanced fabric performance is fundamental to reduce the energy consumption in buildings. Research has shown that the thermal mass of the fabric can be used as…”
Get full text

Evaluation of LES and RANS CFD modelling of multiple steady states in natural ventilation by Durrani, Faisal, Cook, Malcolm J., McGuirk, James J.

“…This paper reports research carried out with the aim of evaluating and comparing the performance of Large Eddy Simulation (LES) and Unsteady Reynolds-Averaged…”
Get full text

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells by Hu, Deqing, Garruss, Alexander S, Gao, Xin, Morgan, Marc A, Cook, Malcolm, Smith, Edwin R, Shilatifard, Ali

“…Embryonic stem cells (ESCs) possess a unique chromatin landscape in which 'bivalent' domains of trimethylated histone H3 Lys4 (H3K4me3) and Lys27 (H3K27me3)…”
Get full text

Natural ventilation strategies for indoor thermal comfort in Mediterranean apartments by Spentzou, Eftychia, Cook, Malcolm J., Emmitt, Stephen

“…Natural ventilation strategies as effective low energy refurbishment solutions are identified within this research study, for an existing urban multi-storey…”
Get full text

A review of ventilation opening area terminology by Jones, Benjamin M., Cook, Malcolm J., Fitzgerald, Shaun D., Iddon, Christopher R.

“…•Definitions of free, effective, and equivalent ventilation opening areas are given.•A review of current definitions highlight contradictions in national…”
Get full text

An empirical study of electricity and gas demand drivers in large food retail buildings of a national organisation by Spyrou, Maria S., Shanks, Kirk, Cook, Malcolm J., Pitcher, James, Lee, Richard

“…•We use regression analysis to calculate the energy demand of food retail stores.•A methodology is reported to identify inefficient food retail…”
Get full text

Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal by Kandola, Tej, Venkatesan, Shriram, Zhang, Jiahui, Lerbakken, Brooklyn T, Von Schulze, Alex, Blanck, Jillian F, Wu, Jianzheng, Unruh, Jay R, Berry, Paula, Lange, Jeffrey J, Box, Andrew C, Cook, Malcolm, Sagui, Celeste, Halfmann, Randal

“…A long-standing goal of amyloid research has been to characterize the structural basis of the rate-determining nucleating event. However, the ephemeral nature…”
Get full text

Practical application of a sensor overlay system for building monitoring and commissioning by Painter, Birgit, Brown, Neil, Cook, Malcolm J.

“…► Standard equipment is used to develop sensor overlay networks for building monitoring. ► Overlay sensors provide data at high spatial resolution. ► Overlay…”
Get full text

Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation by Thornton, Janet L, Westfield, Gerwin H, Takahashi, Yoh-Hei, Cook, Malcolm, Gao, Xin, Woodfin, Ashley R, Lee, Jung-Shin, Morgan, Marc A, Jackson, Jessica, Smith, Edwin R, Couture, Jean-Francois, Skiniotis, Georgios, Shilatifard, Ali

“…The stimulation of trimethylation of histone H3 Lys4 (H3K4) by H2B monoubiquitination (H2Bub) has been widely studied, with multiple mechanisms having been…”
Get full text

Publisher Correction: The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution by Smith, Jeramiah J., Timoshevskaya, Nataliya, Ye, Chengxi, Holt, Carson, Keinath, Melissa C., Parker, Hugo J., Cook, Malcolm E., Hess, Jon E., Narum, Shawn R., Lamanna, Francesco, Kaessmann, Henrik, Timoshevskiy, Vladimir A., Waterbury, Courtney K. M., Saraceno, Cody, Wiedemann, Leanne M., Robb, Sofia M. C., Baker, Carl, Eichler, Evan E., Hockman, Dorit, Sauka-Spengler, Tatjana, Yandell, Mark, Krumlauf, Robb, Elgar, Greg, Amemiya, Chris T.

“…When published, this article did not initially appear open access. This error has been corrected, and the open access status of the paper is noted in all…”
Get full text

Low energy architecture for a severe US climate: Design and evaluation of a hybrid ventilation strategy by Lomas, Kevin J., Cook, Malcolm J., Fiala, Dusan

“…Natural ventilation, relying on openings in the façade, is applicable to a limited range of climates, sites and building types. Advanced naturally ventilated…”
Get full text

Publisher Correction: The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution by Smith, Jeramiah J., Timoshevskaya, Nataliya, Ye, Chengxi, Holt, Carson, Keinath, Melissa C., Parker, Hugo J., Cook, Malcolm E., Hess, Jon E., Narum, Shawn R., Lamanna, Francesco, Kaessmann, Henrik, Timoshevskiy, Vladimir A., Waterbury, Courtney K. M., Saraceno, Cody, Wiedemann, Leanne M., Robb, Sofia M. C., Baker, Carl, Eichler, Evan E., Hockman, Dorit, Sauka-Spengler, Tatjana, Yandell, Mark, Krumlauf, Robb, Elgar, Greg, Amemiya, Chris T.

“…In the version of this article initially published, the present addresses for authors Dorit Hockman and Chris Amemiya were switched. The error has been…”
Get full text

A statistical framework for consolidating "sibling" probe sets for Affymetrix GeneChip data by Li, Hua, Zhu, Dongxiao, Cook, Malcolm

“…Affymetrix GeneChip typically contains multiple probe sets per gene, defined as sibling probe sets in this study. These probe sets may or may not behave…”
Get full text

Numerical study of transitional separated-reattached flow over surface-mounted obstacles using large-eddy simulation by Abdalla, Ibrahim E., Cook, Malcolm J., Yang, Zhiyin

“…Large‐eddy simulation (LES) of transitional separating–reattaching flow on a square surface mounted obstacle has been performed. The Reynolds number based on…”
Get full text