Search Results - "Cook, Kelsey D"

Ionization Mechanism of Positive-Ion Direct Analysis in Real Time: A Transient Microenvironment Concept by Song, Liguo, Gibson, Stephen C, Bhandari, Deepak, Cook, Kelsey D, Bartmess, John E

“…A transient microenvironment mechanism (TMEM) is proposed to address matrix effects for direct analysis in real time (DART). When the DART gas stream is in…”
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Fluorometric Measurement and Modeling of Droplet Temperature Changes in an Electrospray Plume by Gibson, Stephen C, Feigerle, Charles S, Cook, Kelsey D

“…The evolution of droplet temperatures in an electrospray plume was measured via ratiometric fluorescence. Under typical operating conditions, droplet…”
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Structural Properties of Aβ Protofibrils Stabilized by a Small Molecule by Williams, Angela D., Sega, Matt, Chen, Maolian, Kheterpal, Indu, Geva, Merav, Berthelier, Valerie, Kaleta, David T., Cook, Kelsey D., Wetzel, Ronald, Wickner, Reed B.

“…Metastable oligomeric and protofibrillar forms of amyloidogenic proteins have been implicated as on-pathway assembly intermediates in amyloid formation and as…”
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Thoughts on Writing for Review: A Former JASMS Associate Editor’s Perspective by Cook, Kelsey D

“…This is an invited Account and Perspective, providing observations and advice on writing for review derived from a 40-year academic career that has included 27…”
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Thoughts on Writing for Review: An NSF Program Officer’s Perspective by Cook, Kelsey D

“…This is an invited Account and Perspective, providing observations and advice derived from a 40 year academic career that has included over 14 years’ service…”
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Evaluation of direct analysis in real time mass spectrometry for onsite monitoring of batch slurry reactions by Cho, David S., Gibson, Stephen C., Bhandari, Deepak, McNally, Mary Ellen, Hoffman, Ron M., Cook, Kelsey D., Song, Liguo

“…Batch slurry reactions are widely used in the industrial manufacturing of chemicals, pharmaceuticals, petrochemicals and polymers. However, onsite monitoring…”
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Protonation in electrospray mass spectrometry: wrong-way-round or right-way-round? by Zhou, Shaolian, Cook, Kelsey D.

“…The term “wrong-way-round ionization” has been used in studies of electrospray ionization to describe the observation of protonated or deprotonated ions when…”
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Profiling pH Changes in the Electrospray Plume by Zhou, Shaolian, Prebyl, Benjamin S, Cook, Kelsey D

“…Laser-induced fluorescence spectrometry is used to profile pH changes as droplets evaporate in an electrospray plume by measuring emission spectra of 2(or…”
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Oxidation Artifacts in the Electrospray Mass Spectrometry of Aβ Peptide by Chen, Maolian, Cook, Kelsey D

“…Gradual corrosion of stainless steel electrospray emitters under conditions of normal use generates surface irregularities that can promote electrical…”
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Use of Fourier Transform for Deconvolution of the Unresolved Envelope Observed in Electrospray Ionization Mass Spectrometry of Strongly Ionic Synthetic Polymers by Prebyl, Benjamin S, Cook, Kelsey D

“…Fourier transform analysis of electrospray mass spectra of synthetic polymers can be used to obtain information about the monomer mass, charge distribution,…”
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Durable Gold-Coated Fused Silica Capillaries for Use in Electrospray Mass Spectrometry by Kriger, M. Scott, Cook, Kelsey D, Ramsey, Roswitha S

“…A simple procedure for preparing gold-coated silica capillaries for use in electrospray ionization mass spectrometry is described. The tip of the capillary is…”
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Investigation of the Electrospray Plume by Laser-Induced Fluorescence Spectroscopy by Zhou, Shaolian, Edwards, Anna G, Cook, Kelsey D, Van Berkel, Gary J

“…Laser-induced fluorescence spectroscopy has been employed to probe the electrospray plume through measurement of the emission spectra of fluorescent dyes in…”
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Quantitative Real-Time Monitoring of Chemical Reactions by Autosampling Flow Injection Analysis Coupled with Atmospheric Pressure Chemical Ionization Mass Spectrometry by Zhu, Zhenqian, Bartmess, John E, McNally, Mary Ellen, Hoffman, Ron M, Cook, Kelsey D, Song, Liguo

“…Although qualitative and/or semiquantitative real-time monitoring of chemical reactions have been reported with a few mass spectrometric approaches, to our…”
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Characterizing the Range of Extracellular Protein Post-Translational Modifications in a Cellulose-Degrading Bacteria Using a Multiple Proteolyic Digestion/Peptide Fragmentation Approach by Dykstra, Andrew B, Rodriguez, Miguel, Raman, Babu, Cook, Kelsey D, Hettich, Robert L

“…Post-translational modifications (PTMs) are known to play a significant role in many biological functions. The focus of this study is to optimize an integrated…”
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Development of a Multipoint Quantitation Method to Simultaneously Measure Enzymatic and Structural Components of the Clostridium thermocellum Cellulosome Protein Complex by Dykstra, Andrew B, St. Brice, Lois, Rodriguez, Miguel, Raman, Babu, Izquierdo, Javier, Cook, Kelsey D, Lynd, Lee R, Hettich, Robert L

“…Clostridium thermocellum has emerged as a leading bioenergy-relevant microbe due to its ability to solubilize cellulose into carbohydrates, mediated by…”
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Aβ Amyloid Fibrils Possess a Core Structure Highly Resistant to Hydrogen Exchange by Kheterpal, Indu, Zhou, Shaolian, Cook, Kelsey D., Wetzel, Ronald

“…We describe here experiments designed to characterize the secondary structure of amyloid fibrils of the Alzheimer's amyloid plaque peptide Aβ, using…”
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Liquid chromatography/dopant-assisted atmospheric pressure chemical ionization mass spectrometry for the analysis of non-polar compounds by Song, Liguo, Cho, David S., Bhandari, Deepak, Gibson, Stephen C., McNally, Mary Ellen, Hoffman, Ron M., Cook, Kelsey D.

“…[Display omitted] ► LC/DA-APCI-MS was introduced for the analysis of non-polar compounds, i.e., PAHs. ► Chlorobenzene, toluene, anisole were explored as…”
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Complementary Peptide Sequence Coverage Using Alternative Enzymes for On-Line Digestion with a Triaxial Electrospray Probe by Dykstra, Andrew B., Chen, Maolian, Cook, Kelsey D.

“…Using alternative enzymes for on-line digestion with a triaxial electrospray probe extends sequence coverage. This is the first report of utilization of our…”
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A mechanistic study of electrospray mass spectrometry: charge gradients within electrospray droplets and their influence on ion response by Zhou, Shaolian, Cook, Kelsey D

“…A model has been developed to account qualitatively for the effects of ion pairing, surface activity, and electrophoretic mobility in electrospray mass…”
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A Triaxial Probe for On-line Proteolysis Coupled with Hydrogen/Deuterium Exchange-Electrospray Mass Spectrometry by Chen, Maolian, Cook, Kelsey D., Kheterpal, Indu, Wetzel, Ronald

“…An on-line proteolysis system utilizing a triaxial electrospray probe was developed to aid localization of the hydrogen-bonding interaction sites in…”
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