Search Results - "Cook, J R"
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The clinical and economic costs associated with regional disparities in varicella vaccine coverage in Italy over 50 years (2020–2070)
Published in Scientific reports (24-05-2024)“…Italy implemented two-dose universal varicella vaccination (UVV) regionally from 2003 to 2013 and nationally from 2017 onwards. Our objective was to analyze…”
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Oncogenically active MYD88 mutations in human lymphoma
Published in Nature (London) (03-02-2011)“…MYD88 signalling in cancer RNA interference screening and high-throughput RNA resequencing have been used to reveal oncogenic mutations in the signalling…”
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Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
Published in Nature (London) (07-01-2010)“…A role for B-cell-receptor (BCR) signalling in lymphomagenesis has been inferred by studying immunoglobulin genes in human lymphomas and by engineering mouse…”
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Multiple repeat caesarean section in the UK: incidence and consequences to mother and child. A national, prospective, cohort study
Published in BJOG : an international journal of obstetrics and gynaecology (01-01-2013)“…Objective To estimate the incidence of multiple repeat caesarean section (MRCS) (five or more) in the UK and to describe the outcomes for women and their…”
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Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations
Published in The European respiratory journal (01-03-2006)“…One important goal of asthma treatment is to reduce exacerbations. The current authors investigated if the use of sputum cell counts to guide treatment would…”
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Imaging body composition in cancer patients: visceral obesity, sarcopenia and sarcopenic obesity may impact on clinical outcome
Published in Insights into imaging (01-08-2015)“…In recent years, there has been increasing interest in the influence of body composition on oncological patient outcomes. Visceral obesity, sarcopenia and…”
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Molecular imaging of hypoxia in non-small-cell lung cancer
Published in European journal of nuclear medicine and molecular imaging (01-05-2015)“…Non-small-cell lung cancer (NSCLC) is the commonest cancer worldwide but survival remains poor with a high risk of relapse, particularly after nonsurgical…”
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Prognostic variables for survival and skeletal complications in patients with multiple myeloma osteolytic bone disease
Published in Leukemia (01-05-2010)“…Skeletal-related events (SREs) are common in patients with osteolytic lesions from multiple myeloma (MM), and result in substantial morbidity. We report herein…”
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Inter-rater and intra-rater agreement of [99mTc]-labelled NM-01, a single-domain programmed death-ligand 1 (PD-L1) antibody, using quantitative SPECT/CT in non-small cell lung cancer
Published in EJNMMI research (31-05-2023)“…Background Immune checkpoint inhibitors, including those against programmed cell death protein-1 (PD-1) or its ligand (PD-L1), are routinely used to treat…”
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Teriparatide Promotes Bone Healing in Medication-Related Osteonecrosis of the Jaw: A Placebo-Controlled, Randomized Trial
Published in Journal of clinical oncology (10-09-2020)“…Medication-related osteonecrosis of the jaw (MRONJ) is an infrequent but morbid and potentially serious condition associated with antiresorptive and…”
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Radiomic assessment of oesophageal adenocarcinoma: a critical review of 18F-FDG PET/CT, PET/MRI and CT
Published in Insights into imaging (17-06-2022)“…Objectives Radiomic models present an avenue to improve oesophageal adenocarcinoma assessment through quantitative medical image analysis. However, model…”
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Utility of a simplified [18F] sodium fluoride PET imaging method to quantify bone metabolic flux for a wide range of clinical applications
Published in Frontiers in endocrinology (Lausanne) (13-09-2023)“…We review the rationale, methodology, and clinical utility of quantitative [ 18 F] sodium fluoride ([ 18 F]NaF) positron emission tomography-computed…”
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Cardiovascular manifestations in Marfan syndrome and related diseases; multiple genes causing similar phenotypes
Published in Clinical genetics (01-01-2015)“…Cardiovascular abnormalities are the major cause of morbidity and mortality in Marfan syndrome (MFS) and a few clinically related diseases that share, with…”
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Group O RBCs: where is universal donor blood being used
Published in Vox sanguinis (01-05-2017)“…Background There have been recurrent shortages of group O blood due to insufficient inventory and use of group O blood in ABO non‐identical recipients. We…”
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Second auto-SCT is safe and effective salvage therapy for relapsed multiple myeloma
Published in Bone marrow transplantation (Basingstoke) (01-03-2009)“…Therapeutic options for patients with multiple myeloma whose disease has relapsed after a prior auto-SCT include novel biologic therapies, traditional…”
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Standardisation of conventional and advanced iterative reconstruction methods for Gallium-68 multi-centre PET-CT trials
Published in EJNMMI physics (17-07-2021)“…Purpose To assess the applicability of the Fluorine-18 performance specifications defined by EANM Research Ltd (EARL), in Gallium-68 multi-centre PET-CT trials…”
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[99mTc]-labelled anti-Programmed Death-Ligand 1 single-domain antibody SPECT/CT: a novel imaging biomarker for myocardial PD-L1 expression
Published in EJNMMI research (17-05-2023)“…Background Myocardial programmed death-ligand 1 (PD-L1) expression is implicated in immune checkpoint inhibitor (ICI)-associated myocarditis. Measurement of…”
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Statistical methods for incomplete data: Some results on model misspecification
Published in Statistical methods in medical research (01-02-2017)“…Inverse probability weighted estimating equations and multiple imputation are two of the most studied frameworks for dealing with incomplete data in clinical…”
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Optimisation of CT protocols in PET-CT across different scanner models using different automatic exposure control methods and iterative reconstruction algorithms
Published in EJNMMI physics (31-07-2021)“…Background A significant proportion of the radiation dose from a PET-CT examination is dependent on the CT protocol, which should be optimised for clinical…”
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