Search Results - "Cook, E.B."

Modulation of Eosinophil Responsiveness to TSLP-Mediated Degranulation by Cook, E.B, Stahl, J.L, Schwantes, E.A, Barney, N.P, Mathur, S.A

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Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics by Cook, E.B., Stahl, J.L., Lowe, L., Chen, R., Morgan, E., Wilson, J., Varro, R., Chan, A., Graziano, F.M., Barney, N.P.

“…Tears play an essential role in maintaining corneal and conjunctival integrity by providing a tightly regulated, optimal extracellular environment critical to…”
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TSLP Enhances Barrier Function in Human Conjunctival Epithelial Cells by Cook, E.B, Stahl, J.L, Schwantes, E.A, Graziano, F.M, Mathur, S.K

“…For barrier function studies, HCE (IOBA-NHC cell line) were cultured (multi-layers) on cell culture inserts and stimulated with various concentrations of TSLP…”
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Shedding of the Soluble Receptor for TNFα, TNFR1, is Inhibited by the TACE Inhibitor TAPI2 in Conjunctival Epithelial Cells by Cook, E.B, Stahl, J.L, Barney, N.P, Graziano, F.M

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Thymic Stromal Lymphopoietin Directly Activates Eosinophil Degranulation by Cook, E.B, Stahl, J.L, Schwantes, E.A, Koziol-White, C.J, Bertics, P.J, Graziano, F.M, Mathur, S.K

“…[...]in allergic inflammation, multiple pathways can serve to activate eosinophils, perhaps in a synergistic manner…”
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Differential Regulation of Conjunctival Epithelial Permeability by Staphylococcus Enterotoxin B, Platelet Activating Factor, and IL-8 by Cook, E.B, Stahl, J.L, Barney, N.P, Graziano, F.M

“…The purpose of this study was to examine regulation of human conjunctival epithelial (HCE) permeability in response to SEB in comparison to endogenous stimuli…”
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Eosinophil Adhesion to Junctional Adhesion Molecules In Vitro by Cook, E.B, Stahl, J.L, Fox, K.E, Sedgwick, J.B, Barney, N.P, Graziano, F.M

“…Results Unstimulated eosinophil adhesion to recombinant JAM-A, B, or C was increased compared to uncoated wells (p < 0.05). [...]eosinophils stimulated with…”
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Conjunctival Epithelial Cell Mediators Inhibit Cytokine Release from Activated CD4+ T Cells by Stahl, J.L, Cook, E.B, Schwantes, E.A, Mathur, S.K, Barney, N.P, Graziano, F.M

“…Methods Peripheral blood CD4+ T cells were activated with anti-CD3/CD28 coated beads in buffer or supernates from a human conjunctival epithelial cell line…”
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Comparison of ICAM-1, HLA-DR, TLR2, and TNFR1 Expression in Response to Staphylococcus aureus and Pro-Inflammatory Cytokines between Primary Conjunctival Epithelial Cells and the Cell Line, IOBA-NHC by Stahl, J.L, Cook, E.B, Barney, N.P, Graziano, F.M

“…The purpose of this study was to evaluate how this cell line compares phenotypically to well-characterized responses in primary cultures of conjunctival…”
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Characterization of Responses of Human Nasal Epithelial Cells to Pro-inflammatory Mediators and Secretagogues by Stahl, J.L., Cook, E.B., Graziano, F.M.

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Mechanisms of antihistamines and mast cell stabilizers in ocular allergic inflammation by Cook, E B, Stahl, J L, Barney, N P, Graziano, F M

“…Mast cells play a central role in allergic reactions and inflammation. Successful anti-allergic therapies have typically targeted mast cell mediators,…”
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Regulation of the soluble receptor for TNFα on conjunctival epithelial cells and correlation with ICAM-1 upregulation by TNFα and IgE-activated conjunctival mast cells by Stahl, J.L., Cook, E.B., Barney, N.P., Graziano, F.M.

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Interaction of Staphylococcus aureus peptidoglycan with toll-like receptor 2, but not platelet activating factor receptor, promotes TNFα release from human conjunctival epithelial cells by Cook, E.B., Stahl, J.L., Barney, N.P., Graziano, F.M.

“…Staphylococcus aureus (SA) bacteria are found in large colony counts on the skin of 90% of patients with atopic dermatitis and could play a role in the…”
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Staphylococcus aureus peptidoglycan upregulates expression of toll-like receptor 2, CD14, ICAM-1, HLA-DR and release of TNFα and IL-8 from human conjunctival epithelial cells by Cook, E.B., Stahl, J.L., Graziano, F.M., Barney, N.P.

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Ocular Olopatadine Treatment of Seasonal Allergic Conjunctivitis Decreases the Ability of Tears to Promote In Vitro Eosinophil Adhesion to Tear-Stimulated Conjun ctival Epithelial Cells by Cook, E.B., Stahl, J.L., Sedgwick, J.B., Brooks, A.M., Graziano, F.M., Barney, N.P.

“…Olopatadine treatment significantly inhibited the ability of tears to promote eosinophil adhesion resulting in a net decrease of 486.84 ±116.45 eosinophils/cm2…”
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In vivo expression of toll-like receptor-2 on conjunctival epithelial cells is increased in atopic keratoconjunctivitis by Cook, E.B., Stahl, J.L., Graziano, F.M., Barney, N.P.

“…Conjunctival mast cells were challenged with anti-IgE antibody to obtain activated mast cell supernates, which were then incubated (24 hrs) with HCE…”
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Olopatadine inhibits histamine-stimulated IL-8 release from human nasal epithelial cells in vitro by Graziano, F.M., Stahl, J.L., Barney, N.P., Cook, E.B.

“…The purpose of these studies was to examine the effect of histamine on human nasal epithelial cell (HNE) surface receptor expression (ICAM-1 and HLA) and…”
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Upregulation of eosinophil adhesion to conjunctival epithelial cells by allergic tears is inhibited by treatment with olopatadine by Stahl, J.L., Cook, E.B., Brooks, A.M., Graziano, F.M., Barney, N.P.

“…The mechanism by which eosinophils adhere to the ocular surface during allergic inflammation is unknown. This study examined whether tears from allergic…”
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Olopatadine inhibits conjunctival mast cell-mediated and fMLP stimulated eosinophil degranulation but not mast cell-mediated adhesion of IL-5 primed eosinophils by Stahl, J.L., Cook, E.B., Sedgwick, J.B., Kito, H., Barney, N.P., Graziano, F.M.

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The effect of endotoxin on skeletal muscle protein gene expression in the rat by Macallan, D.C., Cook, E.B., Preedy, V.R., Griffin, G.E.

“…Sepsis is associated with net breakdown of skeletal muscle protein, mediated partly by reduced rates of muscle protein synthesis. This study investigated the…”
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