Search Results - "Cook, Boaz"

The role of Drosophila Piezo in mechanical nociception by Kim, Sung Eun, Coste, Bertrand, Chadha, Abhishek, Cook, Boaz, Patapoutian, Ardem

“…The Drosophila Piezo protein is shown to function in sensory neurons to transduce mechanical force in vivo . Piezo ion channel feels the force Many tissues are…”
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TRP Channel Proteins and Signal Transduction by Minke, Baruch, Cook, Boaz

“…Department of Physiology and the Kühne Minerva Center for Studies of Visual Transduction, The Hebrew University-Hadassah Medical School, Jerusalem, Israel…”
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The effect of stress on motor function in Drosophila by Chadha, Abhishek, Cook, Boaz

“…Exposure to unpredictable and uncontrollable conditions causes animals to perceive stress and change their behavior. It is unclear how the perception of stress…”
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Ionic leakage underlies a gain-of-function effect of dominant disease mutations affecting diverse P-type ATPases by Kaneko, Maki, Desai, Bela S, Cook, Boaz

“…Boaz Cook and colleagues show that dominant disease-causing mutations in genes encoding P-type ATPases result in a gain-of-function ionic leakage phenotype…”
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Dissection of gain control mechanisms in Drosophila mechanotransduction by Chadha, Abhishek, Cook, Boaz

“…Mechanoreceptor cells respond to a vast span of stimulus intensities, which they transduce into a limited response-range using a dynamic regulation of…”
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NOMPC-dependent mechanotransduction shapes the dendrite of proprioceptive neurons by Chadha, Abhishek, Kaneko, Maki, Cook, Boaz

“…•NOMPC mediates mechanotransduction in joint proprioceptive neurons.•NOMPC is localized in the same subcellular compartment which features the previously…”
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The stum Gene Is Essential for Mechanical Sensing in Proprioceptive Neurons by Desai, Bela S., Chadha, Abhishek, Cook, Boaz

“…Animal locomotion depends on proprioceptive feedback, which is generated by mechanosensory neurons. We performed a genetic screen for impaired walking in…”
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A Migrating Ciliary Gate Compartmentalizes the Site of Axoneme Assembly in Drosophila Spermatids by Basiri, Marcus L., Ha, Andrew, Chadha, Abhishek, Clark, Nicole M., Polyanovsky, Andrey, Cook, Boaz, Avidor-Reiss, Tomer

“…In most cells, the cilium is formed within a compartment separated from the cytoplasm. Entry into the ciliary compartment is regulated by a specialized gate…”
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Ionic leakage underlies a gain-of-function effect of dominant disease mutations affecting diverse P-type ATPases by Kaneko, Maki, Desai, Bela S, Cook, Boaz

“…Type II P-type ATPases (PAIIs) constitute a family of conserved proteins that actively generate ionic gradients across membranes. Mutations in genes encoding…”
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Calmodulin regulation of light adaptation and store-operated dark current in Drosophila photoreceptors by Arnon, A. (The Hebrew University, Jerusalem, Israel.), Cook, B, Gillo, B, Montell, C, Selinger, Z, Minke, B

“…Phototransduction in Drosophila occurs through inositol lipid signaling that results in Ca(2+) mobilization. In this system, we investigate the hitherto…”
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Coding of Sweet, Bitter, and Umami Tastes: Different Receptor Cells Sharing Similar Signaling Pathways by Zhang, Yifeng, Hoon, Mark A., Chandrashekar, Jayaram, Mueller, Ken L., Cook, Boaz, Wu, Dianqing, Zuker, Charles S., Ryba, Nicholas J.P.

“…Mammals can taste a wide repertoire of chemosensory stimuli. Two unrelated families of receptors (T1Rs and T2Rs) mediate responses to sweet, amino acids, and…”
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Photoreceptors in evolution and disease by Cook, Boaz, Zelhof, Andrew C

“…A new study identifies the gene that, when mutated, causes autosomal recessive retinitis pigmentosa 25 (arRP25). The RP25 gene encodes an ortholog of…”
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The role of Drosophila Piezo in mechanical nociception by Kim, Sung Eun, Coste, Bertrand, Chadha, Abhishek, Cook, Boaz, Patapoutian, Ardem

“…Transduction of mechanical stimuli by receptor cells is essential for senses such as hearing, touch and pain (1-4). Ion channels have a role in neuronal…”
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Preserving cell shape under environmental stress by McConnaughey, William B, Hardy, Robert W, Zuker, Charles S, Cook, Boaz

“…Maintaining cell shape and tone is crucial for the function and survival of cells and tissues. Mechanotransduction relies on the transformation of minuscule…”
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Metabolic Stress Reversibly Activates the Drosophila Light-Sensitive Channels TRP and TRPL In Vivo by Agam, Keren, von Campenhausen, Mark, Levy, Simon, Ben-Ami, Hagit Cohen, Cook, Boaz, Kirschfeld, Kuno, Minke, Baruch

“…Drosophila transient receptor potential (TRP) is a prototypical member of a novel family of channel proteins underlying phosphoinositide-mediated Ca(2+) entry…”
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Phospholipase C and termination of G-protein-mediated signalling in vivo by Minke, Baruch, Cook, Boaz, Bar-Yaacov, Margalit, Cohen Ben-Ami, Hagit, Goldstein, Robert E, Paroush, Ze'ev, Selinger, Zvi

“…In Drosophila photoreceptors, phospholipase C (PLC) and other signalling components form multiprotein structures through the PDZ scaffold protein INAD…”
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Calmodulin Regulation of Calcium Stores in Phototransduction of Drosophila by Arnon, Assaf, Cook, Boaz, Montell, Craig, Selinger, Zvi, Minke, Baruch

“…Phototransduction in Drosophila occurs through the ubiquitous phosphoinositide-mediated signal transduction system. Major unresolved questions in this pathway…”
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Coding of Sweet, Bitter, and Umami Tastes by Zhang, Yifeng, Hoon, Mark A., Chandrashekar, Jayaram, Mueller, Ken L., Cook, Boaz, Wu, Dianqing, Zuker, Charles S., Ryba, Nicholas J.P.

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Metabolic Stress Reversibly Activates the DrosophilaLight-Sensitive Channels TRP and TRPL In Vivo by Agam, Keren, von Campenhausen, Mark, Levy, Simon, Ben-Ami, Hagit Cohen, Cook, Boaz, Kirschfeld, Kuno, Minke, Baruch

“…Drosophila transient receptor potential (TRP) is a prototypical member of a novel family of channel proteins underlying phosphoinositide-mediated Ca 2+ entry…”
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