Search Results - "Cook, Adam W"

Continuous Additive Manufacturing using Olefin Metathesis by Foster, Jeffrey C., Cook, Adam W., Monk, Nicolas T., Jones, Brad H., Appelhans, Leah N., Redline, Erica M., Leguizamon, Samuel C.

“…The development of chemistry is reported to implement selective dual‐wavelength olefin metathesis polymerization for continuous additive manufacturing (AM). A…”
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Employing Photosensitizers for Rapid Olefin Metathesis Additive Manufacturing of Poly(dicyclopentadiene) by Leguizamon, Samuel C, Cook, Adam W, Appelhans, Leah N

“…The additive manufacturing (AM) of thermoset polymers has been limited primarily to radical or cationic photopolymerizations, restricting available resins and…”
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3D Printing of Ridged FeS2 Cathodes for Improved Rate Capability and Custom-Form Lithium Batteries by Cardenas, Jorge A., Bullivant, John P., Kolesnichenko, Igor V., Roach, Devin J., Gallegos, Michael A., Coker, Eric N., Lambert, Timothy N., Allcorn, Eric, Talin, A. Alec, Cook, Adam W., Harrison, Katharine L.

“…Additive manufacturing can enable the fabrication of batteries in nonconventional form factors, enabling higher practical energy density due to improved…”
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SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy by Drilon, Alexander, Sharma, Manish R, Johnson, Melissa L, Yap, Timothy A, Gadgeel, Shirish, Nepert, Dale, Feng, Gang, Reddy, Micaela B, Harney, Allison S, Elsayed, Mohamed, Cook, Adam W, Wong, Christina E, Hinklin, Ronald J, Jiang, Yutong, Brown, Eric N, Neitzel, Nickolas A, Laird, Ellen R, Wu, Wen-I, Singh, Anurag, Wei, Ping, Ching, Keith A, Gaudino, John J, Lee, Patrice A, Hartley, Dylan P, Rothenberg, S Michael

“…Rationally targeted therapies have transformed cancer treatment, but many patients develop resistance through bypass signaling pathway activation. PF-07284892…”
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Utilizing computer vision and artificial intelligence algorithms to predict and design the mechanical compression response of direct ink write 3D printed foam replacement structures by Roach, Devin J., Rohskopf, Andrew, Hamel, Craig M., Reinholtz, William D., Bernstein, Robert, Qi, H. Jerry, Cook, Adam W.

“…Additive Manufacturing (AM) of porous polymeric materials, such as foams, recently became a topic of intensive research due their unique combination of low…”
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Crystallization of electrically conductive visibly transparent ITO thin films by wavelength-range-specific pulsed Xe arc lamp annealing by Plumley, John B., Cook, Adam W., Larsen, Christopher A., Artyushkova, Kateryna, Han, Sang M., Peng, Thomas L., Kemp, Richard A.

“…Transparent electric conductors made of indium tin oxide (ITO)-doped glass prepared by a flash lamp annealing (FLA) process were compared with ITO-doped glass…”
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Discovery of 5‑Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors by Elsayed, Mohamed S. A., Blake, James F., Boys, Mark L., Brown, Eric, Chapsal, Bruno D., Chicarelli, Mark J., Cook, Adam W., Fell, Jay B., Fischer, John P., Hanson, Lauren, Lemieux, Christine, Martinson, Matthew C., McCown, Joseph, McNulty, Oren T., Mejia, Macedonio J., Neitzel, Nickolas A., Otten, Jennifer N., Rodriguez, Martha E., Wilcox, Daniel, Wong, Christina E., Zhou, Yeyun, Hinklin, Ronald J.

“…SHP2 has emerged as an important target for oncology small-molecule drug discovery. As a nonreceptor tyrosine phosphatase within the MAPK pathway, it has been…”
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Real‐Time Optical Process Monitoring for Structure and Property Control of Aerosol Jet Printed Functional Materials by Tafoya, Rebecca R., Cook, Adam W., Kaehr, Bryan, Downing, Julia R., Hersam, Mark C., Secor, Ethan B.

“…Aerosol jet printing is a popular digital additive manufacturing method for flexible and hybrid electronics, but it lacks sophisticated real‐time process…”
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Spirocyclic β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species by Hunt, Kevin W, Cook, Adam W, Watts, Ryan J, Clark, Christopher T, Vigers, Guy, Smith, Darin, Metcalf, Andrew T, Gunawardana, Indrani W, Burkard, Michael, Cox, April A, Geck Do, Mary K, Dutcher, Darrin, Thomas, Allen A, Rana, Sumeet, Kallan, Nicholas C, DeLisle, Robert K, Rizzi, James P, Regal, Kelly, Sammond, Douglas, Groneberg, Robert, Siu, Michael, Purkey, Hans, Lyssikatos, Joseph P, Marlow, Allison, Liu, Xingrong, Tang, Tony P

“…A hallmark of Alzheimer’s disease is the brain deposition of amyloid beta (Aβ), a peptide of 36–43 amino acids that is likely a primary driver of…”
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Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer by Fell, Jay B, Fischer, John P, Baer, Brian R, Blake, James F, Bouhana, Karyn, Briere, David M, Brown, Karin D, Burgess, Laurence E, Burns, Aaron C, Burkard, Michael R, Chiang, Harrah, Chicarelli, Mark J, Cook, Adam W, Gaudino, John J, Hallin, Jill, Hanson, Lauren, Hartley, Dylan P, Hicken, Erik J, Hingorani, Gary P, Hinklin, Ronald J, Mejia, Macedonio J, Olson, Peter, Otten, Jennifer N, Rhodes, Susan P, Rodriguez, Martha E, Savechenkov, Pavel, Smith, Darin J, Sudhakar, Niranjan, Sullivan, Francis X, Tang, Tony P, Vigers, Guy P, Wollenberg, Lance, Christensen, James G, Marx, Matthew A

“…Capping off an era marred by drug development failures and punctuated by waning interest and presumed intractability toward direct targeting of KRAS, new…”
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Identification of the Clinical Development Candidate MRTX849 , a Covalent KRAS G12C Inhibitor for the Treatment of Cancer by Fell, Jay B, Fischer, John P, Baer, Brian R, Blake, James F, Bouhana, Karyn, Briere, David M, Brown, Karin D, Burgess, Laurence E, Burns, Aaron C, Burkard, Michael R, Chiang, Harrah, Chicarelli, Mark J, Cook, Adam W, Gaudino, John J, Hallin, Jill, Hanson, Lauren, Hartley, Dylan P, Hicken, Erik J, Hingorani, Gary P, Hinklin, Ronald J, Mejia, Macedonio J, Olson, Peter, Otten, Jennifer N, Rhodes, Susan P, Rodriguez, Martha E, Savechenkov, Pavel, Smith, Darin J, Sudhakar, Niranjan, Sullivan, Francis X, Tang, Tony P, Vigers, Guy P, Wollenberg, Lance, Christensen, James G, Marx, Matthew A

“…Capping off an era marred by drug development failures and punctuated by waning interest and presumed intractability toward direct targeting of KRAS, new…”
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Aqueous Stability of Mesoporous Silica Films Doped or Grafted with Aluminum Oxide by Dunphy, Darren R, Singer, Sarany, Cook, Adam W, Smarsly, Bernd, Doshi, Dhaval A, Brinker, C. Jeffrey

“…Surfactant-templated silica thin films are potentially important materials for applications such as chemical sensing. However, a serious limitation for their…”
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Compositional effects on cure kinetics, mechanical properties and printability of dual-cure epoxy/acrylate resins for DIW additive manufacturing by Kopatz, Jessica W., Unangst, Jaclynn, Cook, Adam W., Appelhans, Leah N.

“…Interest in 3D printing of thermoset resins has increased significantly in recent years. One approach to additive manufacturing of thermoset resins is printing…”
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Monodomain Liquid‐Crystal Elastomer Lattices for Broad Strain‐Rate Mechanical Damping by Bischoff, Adam, Bawcutt, Carter, Sorkin, Maksim, Yazzie, Joel, C. Cook, Caitlyn, Leguizamon, Samuel C., Cook, Adam W., Roach, Devin J.

“…Designing structures that effectively dissipate energy across a broad range of mechanical loading rates, including those from compression, shock, and…”
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Invertible neural networks for real-time control of extrusion additive manufacturing by Roach, Devin J., Rohskopf, Andrew, Leguizamon, Samuel, Appelhans, Leah, Cook, Adam W.

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Pressure-based process monitoring of direct-ink write material extrusion additive manufacturing by Kopatz, Jessica W., Reinholtz, Derek, Cook, Adam W., Tappan, Alexander S., Grillet, Anne M.

“…As additive manufacturing (AM) has become a reliable method for creating complex and unique hardware rapidly, the quality assurance of printed parts remains a…”
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Pressure-based process monitoring of direct-ink write material extrusion additive manufacturing by Kopatz, Jessica Whitney, Reinholtz, William Derek, Cook, Adam W., Tappan, Alexander Smith, Grillet, Anne Mary

“…As additive manufacturing (AM) has become a reliable method for creating complex and unique hardware rapidly, the quality assurance of printed parts remains a…”
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In situ characterization of material extrusion printing by near-infrared spectroscopy by Linde, Erik, Celina, Mathew C., Appelhans, Leah N., Roach, Devin J., Cook, Adam W.

“…Material extrusion printing of reactive resins and inks present a unique challenge due to the time-dependent nature of the rheological and chemical properties…”
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Invertible neural networks for real-time control of extrusion additive manufacturing by Roach, Devin John, Rohskopf, Andrew Dale, Leguizamon, Samuel, Appelhans, Leah, Cook, Adam W.

“…Material extrusion additive manufacturing (AM) has enabled an elegant fabrication pathway for a vast material library. Nonetheless, each material requires…”
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3D Printing of Ridged FeS 2 Cathodes for Improved Rate Capability and Custom-Form Lithium Batteries by Cardenas, Jorge A., Bullivant, John P., Kolesnichenko, Igor V., Roach, Devin J., Gallegos, Michael A., Coker, Eric N., Lambert, Timothy N., Allcorn, Eric, Talin, A. Alec, Cook, Adam W., Harrison, Katharine L.

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