Search Results - "Conway, Thomas F"

Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease by Conway, Thomas F., Hammer, Laura, Furtado, Stacia, Mathiowitz, Edith, Nicoletti, Ferdinando, Mangano, Katia, Egilmez, Nejat K., Auci, Dominick L.

“…Background and aims: We investigated oral delivery of transforming growth factor beta 1 [TGFβ]- and all-trans retinoic acid [ATRA]-loaded microspheres as…”
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Cancer immunotherapy with interleukin 12 and granulocyte-macrophage colony-stimulating factor-encapsulated microspheres: Coinduction of innate and adaptive antitumor immunity and cure of disseminated disease by HILL, Hank C, CONWAY, Thomas F, SABEL, Michael S, JONG, Yong S, MATHIOWITZ, Edith, BANKERT, Richard B, EGILMEZ, Nejat K

“…Tumor cells, injected s.c., were maintained until spontaneous metastases to the lungs were established in all of the mice. Mice were then treated with a single…”
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Memory T Cells in the Chronic Inflammatory Microenvironment of Nasal Polyposis are Hyporesponsive to Signaling Through the T Cell Receptor by Lehman, Heather K., Simpson-Abelson, Michelle R., Conway, Thomas F., Kelleher, Raymond J., Bernstein, Joel M., Bankert, Richard B.

“…A majority of T cells from chronic inflammatory tissues derived from patients with nasal polyposis were found to express an effector memory phenotype. We…”
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Oral interleukin-10 alleviates polyposis via neutralization of pathogenic T-regulatory cells by Chung, Allen Y, Li, Qingsheng, Blair, Sarah J, De Jesus, Magdia, Dennis, Kristen L, LeVea, Charles, Yao, Jin, Sun, Yijun, Conway, Thomas F, Virtuoso, Lauren P, Battaglia, Nicholas G, Furtado, Stacia, Mathiowitz, Edith, Mantis, Nicholas J, Khazaie, Khashayarsha, Egilmez, Nejat K

“…Immune dysregulation drives the pathogenesis of chronic inflammatory, autoimmune, and dysplastic disorders. While often intended to address localized…”
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CTLA-4 blockade augments human T lymphocyte-mediated suppression of lung tumor xenografts in SCID mice by SABEL, Michael S, HESS, Stephen D, EGILMEZ, Nejat K, CONWAY, Thomas F, CHEN, Fang-An, BANKERT, Richard B

“…Previous studies by others using transplantable murine tumor models have demonstrated that the administration of antibodies that block CTLA-4 interaction with…”
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B cell tumor vaccine enhanced by covalent attachment of immunoglobulin to surface proteins on dendritic cells by Lou, Qiang, Conway, Thomas F., Egilmez, Nejat K., Loyall, Jenni L., Bernstein, Steven H., Kelleher, Raymond J., Bankert, Richard B.

“…Protein antigens have been covalently linked randomly to surface proteins on immature dendritic cells (DC). This has been achieved under physiological…”
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Controlled-release particulate cytokine adjuvants for cancer therapy by Egilmez, Nejat K, Kilinc, Mehmet O, Gu, Tao, Conway, Thomas F

“…Cytokine therapy can induce tumor regression in cancer patients but systemic administration of cytokines is accompanied with severe toxicity. Loco-regional…”
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Human CD4+ effector T cells mediate indirect interleukin-12- and interferon-γ-dependent suppression of autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice by EGILMEZ, Nejat K, HESS, Stephen D, CHEN, Fang-An, TAKITA, Hiroshi, CONWAY, Thomas F, BANKERT, Richard B

“…A human/severe combined immunodeficient mouse chimeric model was used to demonstrate that peripheral blood leukocytes (PBLs) from a patient with lung cancer…”
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Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice by Simpson-Abelson, Michelle R, Sonnenberg, Gregory F, Takita, Hiroshi, Yokota, Sandra J, Conway, Jr, Thomas F, Kelleher, Jr, Raymond J, Shultz, Leonard D, Barcos, Maurice, Bankert, Richard B

“…Non-disrupted pieces of primary human lung tumor implanted into NOD-scid IL2Rgamma(null) mice consistently result in successful xenografts in which tissue…”
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Growth of human tumor xenografts in SCID mice quantified using an immunoassay for tumor marker protein in serum by Conway, Thomas F, Sabel, Michael S, Sugano, Masahiko, Frelinger, John G, Egilmez, Nejat K, Chen, Fang-An, Bankert, Richard B

“…The accurate measurement of the response of a tumor to a given treatment is critical to evaluating novel therapeutic modalities. An experimental design is…”
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Long-Term Engraftment and Expansion of Tumor-Derived Memory T Cells Following the Implantation of Non-Disrupted Pieces of Human Lung Tumor into NOD-scid IL2Rγnull Mice by Simpson-Abelson, Michelle R., Sonnenberg, Gregory F., Takita, Hiroshi, Yokota, Sandra J., Conway, Thomas F., Kelleher, Raymond J., Shultz, Leonard D., Barcos, Maurice, Bankert, Richard B.

“…Abstract Non-disrupted pieces of primary human lung tumor implanted into NOD-scid IL2Rγnull mice consistently result in successful xenografts in which tissue…”
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Covalent linkage of antigens to plasma membrane proteins on the surface of dendritic cells as a means of enhancing immunogenicity by Conway, Thomas F., Jr

“…Vaccination strategies employing dendritic cells (DCs) have been used extensively in both pre-clinical models as well as in clinical trials for the treatment…”
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The Soc-Maker by Conway, Thomas F.

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Covalent linkage of antigens to plasma membrane proteins on the surface of dendritic cells as a means of enhancing immunogenicity by Conway, Thomas F

“…Vaccination strategies employing dendritic cells (DCs) have been used extensively in both pre-clinical models as well as in clinical trials for the treatment…”
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Monoclonal antibodies directed against the T-cell activation molecule CD137 (interleukin-A or 4-1BB) block human lymphocyte-mediated suppression of tumor xenografts in severe combined immunodeficient mice by SABEL, M. S, CONWAY, T. F, CHEN, F.-A, BANKERT, R. B

“…A monoclonal antibody specific for the human analog of the murine T-cell activation molecule 4-1BB was generated and is shown here to react selectively with…”
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Long-Term Engraftment and Expansion of Tumor-Derived Memory T Cells Following the Implantation of Non-Disrupted Pieces of Human Lung Tumor into NOD-scid IL2R{gamma}null Mice by Simpson-Abelson, Michelle R, Sonnenberg, Gregory F, Takita, Hiroshi, Yokota, Sandra J, Conway, Thomas F., Jr, Kelleher, Raymond J., Jr, Shultz, Leonard D, Barcos, Maurice, Bankert, Richard B

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Genetic changes in quantity and composition of vegetable oils by Elder, Albert L., Rathmann, Dorothy M., Conway, Thomas F.

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