Search Results - "Convertino, Irma"
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Anti-SARS-CoV-2 neutralizing monoclonal antibodies: clinical pipeline
Published in mAbs (01-01-2020)“…Monoclonal antibody (mAb) therapy has been previously exploited for viral infections, such as respiratory syncytial virus pneumonia and Ebolavirus disease. In…”
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Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients
Published in Critical care (London, England) (11-06-2020)“…Sars-CoV-2 complications include pneumonia and acute respiratory distress syndrome (ARDS), which require intensive care unit admission. These conditions have…”
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Drug Safety and Relevant Issues in the Real-World
Published in Pharmaceuticals (Basel, Switzerland) (01-12-2023)“…The global impact of the COVID-19 pandemic has underscored the pivotal role of drug safety and effective communication within the realm of pharmacovigilance,…”
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Validation of algorithms for selecting rheumatoid arthritis patients in the Tuscan healthcare administrative databases
Published in Scientific reports (13-10-2021)“…Validation of algorithms for selecting patients from healthcare administrative databases (HAD) is recommended. This PATHFINDER study section is aimed at…”
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Is There a Risk of Lymphoma Associated With Anti-tumor Necrosis Factor Drugs in Patients With Inflammatory Bowel Disease? A Systematic Review of Observational Studies
Published in Frontiers in pharmacology (19-03-2019)“…Inflammatory bowel diseases (IBDs) are generally not considered a risk factor for the development of lymphoma. When considering IBD treatments, there is good…”
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Assessing disease activity of rheumatoid arthritis patients and drug-utilization patterns of biologic disease-modifying antirheumatic drugs in the Tuscany region, Italy
Published in Frontiers in pharmacology (25-09-2023)“…Introduction: The disease activity associated with the drug-utilization patterns of biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) is poorly…”
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Drug-Utilization, Healthcare Facilities Accesses and Costs of the First Generation of JAK Inhibitors in Rheumatoid Arthritis
Published in Pharmaceuticals (Basel, Switzerland) (01-03-2023)“…This study is aimed at describing tofacitinib and baricitinib users by characterizing their prescription and healthcare histories, drug and healthcare…”
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A Cross-National Comparison of Biosimilars Pricing in Argentina, Australia, Brazil, and Italy
Published in Therapeutic innovation & regulatory science (01-05-2024)“…Biosimilar medicines are defined as biological products highly similar to an already licensed biological product (RP). The market entry of biosimilars is…”
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Diabetes drugs and the incidence of solid cancers: a survey of the current evidence
Published in Expert opinion on drug safety (03-10-2017)“…The evaluation of the relationship between the use of antidiabetic drug and the occurrence of cancer is extremely challenging, both from the clinical and…”
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The Impact of the COVID-19 “Infodemic” on Drug-Utilization Behaviors: Implications for Pharmacovigilance
Published in Drug safety (01-08-2020)“…The coronavirus disease 2019 (COVID-19) pandemic that hit the world in 2020 triggered a massive dissemination of information (an “infodemic”) about the disease…”
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Olfactory and gustatory impairments in COVID‐19 patients: Role in early diagnosis and interferences by concomitant drugs
Published in British journal of clinical pharmacology (01-05-2021)Get full text
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Lessons learnt from the preclinical discovery and development of ensitrelvir as a COVID-19 therapeutic option
Published in Expert opinion on drug discovery (2024)“…The COVID-19 pandemic stimulated the development of several therapeutic tools with several degrees of success. Ensitrelvir, a protease inhibitor that blocks…”
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An overview of the preclinical discovery and development of bamlanivimab for the treatment of novel coronavirus infection (COVID-19): reasons for limited clinical use and lessons for the future
Published in Expert opinion on drug discovery (02-12-2021)“…: In the COVID-19 pandemic emergency, research has been oriented toward the development of therapies that could cure critically ill patients and treatments…”
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Unresolved gustatory, olfactory and auditory adverse drug reactions to antibiotic drugs: a survey of spontaneous reporting to Eudravigilance
Published in Expert opinion on drug safety (02-12-2019)“…: Sensory adverse drug reactions (ADRs) are generally expected to be transient in nature. However, spontaneous reports describe frequently these events as…”
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Tixagevimab + cilgavimab against SARS-CoV-2: the preclinical and clinical development and real-world evidence
Published in Expert opinion on drug discovery (04-03-2023)“…Direct-acting SARS-CoV-2 antiviral monoclonal antibodies have been an integral part of therapeutic strategies against COVID-19 pandemic. The monoclonal…”
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Potential missed diagnoses of Crohn's disease in tertiary care: impact on drug utilization and healthcare facilities use
Published in European journal of gastroenterology & hepatology (01-11-2023)“…A missed diagnosis of Crohn's disease (CD) can delay treatment initiation with consequences on disease course. To measure the possible impact of missed…”
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Potential Direct Costs of Adverse Drug Events and Possible Cost Savings Achievable by their Prevention in Tuscany, Italy: A Model-Based Analysis
Published in Drug safety (01-03-2019)“…Introduction Adverse drug events (ADEs) may represent an important item of expenditure for healthcare systems and their prevention could be associated with a…”
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