Search Results - "Converso, A"
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents
Published in Neuropharmacology (01-09-2011)“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: A Privileged, Bivalent Scaffold for the Display of Nucleophilic Components
Published in Journal of organic chemistry (15-06-2001)“…The title compound, the condensation product of sulfur dichloride and 1,5-cyclooctadiene, is a reliable acceptor of a wide variety of heteroatom nucleophiles,…”
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3
Foreign Direct Investment in Post-Conflict Countries: The Case of Iraq’s Oil and Electricity Sectors
Published in International journal of energy economics and policy (2014)“…Foreign direct investment is new phenomenon to Iraq, a post conflict country with abundance of natural resources. With dominant state-controlled public sector,…”
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Ca2+Activation of Wheat Peroxidase: A Possible Physiological Mechanism of Control
Published in Archives of biochemistry and biophysics (01-09-1996)“…Peroxidation of substrates such as ascorbic acid, pyrogallol, or ferulic acid, as well as indole acetic acid oxidation catalyzed by wheat germ peroxidase…”
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Peroxidase isozymes from wheat germ: purification and properties
Published in Phytochemistry (Oxford) (01-11-1995)“…Several cationic peroxidase isozymes were identified in wheat germ. Three of them were purified to homogeneity. The pure enzymes share many properties; they…”
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Cadmium inhibition of a structural wheat peroxidase
Published in Journal of enzyme inhibition (2000)“…The major peroxidase from 15-day-old wheat plants was purified to homogeneity by FPLC ion exchange and molecular exclusion chromatography. It consists of a…”
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Evidence for an Unusual Electronic Structure of Wheat Germ Peroxidase Compound I
Published in Archives of biochemistry and biophysics (01-09-1998)“…Oxidized states of wheat germ peroxidase isozyme C2 (WGP C2) were investigated by means of electronic absorption spectroscopy. Addition of one molar equivalent…”
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The Selective Phosphodiesterase 9 (PDE9) Inhibitor PF-04447943 Attenuates a Scopolamine-Induced Deficit in a Novel Rodent Attention Task
Published in Journal of neurogenetics (01-12-2011)“…Numerous changes occur during aging and Alzheimer's disease (AD) progression, including a decline in cholinergic functioning and cognition, as well as…”
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Mandatory flu vaccination for heath care workers
Published in The American journal of nursing (01-01-2010)“…Debate between 2 nursing leaders on the introduction of mandatory H1N1 pandemic influenza vaccinations for health care staff in the USA. Benefits and…”
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Comparison of amine additives most effective in the new methyltrioxorhenium-catalyzed epoxidation process
Published in Tetrahedron letters (21-05-1999)“…Three different heterocyclic amine additives, pyridine, 3-cyanopyridine and pyrazole are compared in the methyltrioxorhenium (MTO) catalyzed epoxidation of…”
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Studies toward the Synthesis of Azadirachtin, Part 1: Total Synthesis of a Fully Functionalized ABC Ring Framework and Coupling with a Norbornene Domain
Published in Angewandte Chemie International Edition (30-05-2005)“…The advanced decalin intermediate 1 was synthesized and elaborated into the potential azadirachtin precursor 2. The challenging synthesis involved several…”
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The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(t e trahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4- o n e) enhances synaptic plasticity and cognitive function in rodents
Published in Neuropharmacology (01-09-2011)“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
Get full text
Journal Article -
13
The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3 S,4 S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2 H-pyran-4-yl)-1,5-dihydro-4 H-pyrazolo[3,4- d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents
Published in Neuropharmacology (2011)“…Inhibition of phosphodiesterase 9 (PDE9) has been reported to enhance rodent cognitive function and may represent a potential novel approach to improving…”
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Journal Article -
14
Nucleophilic Substitution by Grignard Reagents on Sulfur Mustards
Published in Journal of organic chemistry (15-10-2004)“…With proper activation of the leaving group, sulfur mustards react with Grignard reagents with neighboring group participation of the sulfur atom…”
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Studies toward the Synthesis of Azadirachtin, Part 2: Construction of Fully Functionalized ABCD Ring Frameworks and Unusual Intramolecular Reactions Induced by Close-Proximity Effects
Published in Angewandte Chemie International Edition (30-05-2005)“…The remarkable antifeedant agent and insecticide, azadirachtin (1), has, to date, escaped a total synthesis. The preparation of an advanced precursor has…”
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Simple and efficient routes for the preparation of isoxazolidinyl nucleosides containing cytosine and 5-methyl-cytosine as new potential anti-HIV drugs
Published in Tetrahedron (01-10-2001)“…A rapid and convenient large-scale strategy for the synthesis of some new isoxazolidinyl nucleosides, as potential antiviral drugs, is reported. In particular,…”
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Improved Process for the Preparation of Nucleosidic Phosphoramidites Using a Safer and Cheaper Activator
Published in Organic process research & development (01-05-2000)“…A new, simplified commercial process for the preparation of nucleosidic phosphoramidites, key raw materials for the automated solid-supported synthesis of…”
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Is your hospital safe?
Published in The American journal of nursing (01-02-2007)“…Hospital nurses are in a position to actively identify workplace hazards and develop strategies for reducing them. Union nurses have collaborated to address…”
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A biophysical characterization of the iron coordination environment in wheat germ peroxidase
Published in Journal of biological inorganic chemistry (01-04-1997)Get full text
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Synthesis of isoxazolidino analogues of 2',3'-dideoxynucleosides
Published in Nucleosides & nucleotides (01-04-1999)“…The complete set of the 4'-aza analogues of 2',3'-dideoxynucleosides was synthesized by cycloaddition of N-tetrahydropiranyl or N-trityl methylene nitrones on…”
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