Search Results - "Conti, J A"

EAES classification of intraoperative adverse events in laparoscopic surgery by Francis, N. K., Curtis, N. J., Conti, J. A., Foster, J. D., Bonjer, H. J., Hanna, G. B.

“…Background Surgical outcomes are traditionally evaluated by post-operative data such as histopathology and morbidity. Although these outcomes are reported…”
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Application of objective clinical human reliability analysis (OCHRA) in assessment of technical performance in laparoscopic rectal cancer surgery by Foster, J. D., Miskovic, D., Allison, A. S., Conti, J. A., Ockrim, J., Cooper, E. J., Hanna, G. B., Francis, N. K.

“…Background Laparoscopic rectal resection is technically challenging, with outcomes dependent upon technical performance. No robust objective assessment tool…”
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Hepatic Arterial Infusion of Chemotherapy after Resection of Hepatic Metastases from Colorectal Cancer by Kemeny, Nancy, Huang, Ying, Cohen, Alfred M, Shi, Weiji, Conti, John A, Brennan, Murray F, Bertino, Joseph R, Turnbull, Alan D.M, Sullivan, Deidre, Stockman, Jennifer, Blumgart, Leslie H, Fong, Yuman

“…Nearly 129,000 patients are given a diagnosis of colorectal cancer each year in the United States, and hepatic metastases develop in 60 percent of these…”
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Irinotecan is an active agent in untreated patients with metastatic colorectal cancer by Conti, J A, Kemeny, N E, Saltz, L B, Huang, Y, Tong, W P, Chou, T C, Sun, M, Pulliam, S, Gonzalez, C

“…To determine the response rate, survival, and toxicity of the new anticancer agent, irinotecan (CPT-11), in the treatment of metastatic colorectal cancer…”
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2D versus 3D laparoscopic total mesorectal excision: a developmental multicentre randomised controlled trial by Curtis, N. J., Conti, J. A., Dalton, R., Rockall, T. A., Allison, A. S., Ockrim, J. B., Jourdan, I. C., Torkington, J., Phillips, S., Allison, J., Hanna, G. B., Francis, N. K.

“…Aims The role of laparoscopy in rectal cancer has been questioned. 3D laparoscopic systems are suggested to aid optimal surgical performance but have not been…”
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A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning by Petiot, Anita, Conti, Francesco J A, Grose, Richard, Revest, Jean-Michel, Hodivala-Dilke, Kairbaan M, Dickson, Clive

“…To understand the role Fgf signalling in skin and hair follicle development, we analysed the phenotype of mice deficient for Fgfr2-IIIb and its main ligand…”
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Relationship of acute gastrointestinal toxicity and the volume of irradiated small bowel in patients receiving combined modality therapy for rectal cancer by Minsky, B D, Conti, J A, Huang, Y, Knopf, K

“…To determine the relationship between acute gastrointestinal (GI) toxicity during the combined modality segment and the volume of small bowel in the pelvic…”
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The selective use of splenic flexure mobilization is safe in both laparoscopic and open anterior resections by Marsden, M. R., Conti, J. A., Zeidan, S., Flashman, K. G., Khan, J. S., O'Leary, D. P., Parvaiz, A.

“…Aim  Splenic flexure mobilization (SFM) is standard practice in anterior resections. No previous studies have compared outcomes with and without SFM in…”
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Phase II study of hepatic arterial floxuridine, leucovorin, and dexamethasone for unresectable liver metastases from colorectal carcinoma by Kemeny, N, Conti, J A, Cohen, A, Campana, P, Huang, Y, Shi, W J, Botet, J, Pulliam, S, Bertino, J R

“…To determine the toxicity, response rate, and survival of a regimen of hepatic arterial floxuridine (FUDR) with leucovorin (LV) and dexamethasone (Dec) for the…”
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A fixed-ratio combination of uracil and Ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer by Saltz, L B, Leichman, C G, Young, C W, Muggia, F M, Conti, J A, Spiess, T, Jeffers, S, Leichman, L P

“…UFT is a fixed-ratio combination of uracil and Ftorafur, a prodrug that is absorbed orally and metabolized in vivo to 5-fluorouracil (5-FU). Uracil potentiates…”
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A comparison of umbilical cord blood gas values between newborns with and without true knots by Maher, John T., Conti, John A.

“…To compare umbilical cord blood gas values in newborns with and without true knots, and to assess the potential impact of true knot formation on cord blood…”
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Trial of sequential trimetrexate, fluorouracil, and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma by Conti, J A, Kemeny, N, Seiter, K, Goker, E, Tong, W, André, M, Ragusa, K, Bertino, J R

“…Trimetrexate (TMTX) is a dihydrofolate reductase inhibitor, which, like methotrexate (MTX), has been shown to potentiate fluorouracil (FU) cytotoxicity by…”
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Acute arterial thrombosis after escalated-dose methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy with recombinant granulocyte colony-stimulating factor. A possible new recombinant granulocyte colony-stimulating factor toxicity by Conti, J A, Scher, H I

“…Combination chemotherapy with a regimen of methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) has produced long-term survival times in a significant…”
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Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer by Kemeny, N, Cohen, A, Seiter, K, Conti, J A, Sigurdson, E R, Tao, Y, Niedzwiecki, D, Botet, J, Budd, A

“…This study was designed to determine if hepatic arterial therapy with floxuridine (F), mitomycin, and carmustine (BCNU) (FMB) is superior to hepatic arterial…”
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Biochemical modulation of bolus fluorouracil by PALA in patients with advanced colorectal cancer by Kemeny, N, Conti, J A, Seiter, K, Niedzwiecki, D, Botet, J, Martin, D, Costa, P, Wiseberg, J, McCulloch, W

“…N-(phosphonacetyl)-L-aspartic acid (PALA) is a pyrimidine synthesis inhibitor that modulates fluorouracil (FU) cytotoxicity. Two previous studies of patients…”
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Colon carcinoma metastatic to the trachea. Report of a case and a review of the literature by Conti, J A, Kemeny, N, Klimstra, D, Minsky, B, Rusch, V

“…Tracheal metastases are rarely seen from colorectal carcinoma. We describe the third reported case of colorectal carcinoma metastatic to the trachea and review…”
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Cancer chemotherapy in the elderly by Conti, J A, Christman, K

“…Gastrointestinal malignancies are very common in the elderly of the U.S. There is controversy about the role of chemotherapy in these elderly patients because…”
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Continuous infusion fluorouracil/leucovorin and bolus mitomycin-C as a salvage regimen for patients with advanced colorectal cancer by Conti, J A, Kemeny, N E, Saltz, L B, André, A M, Grossano, D D, Bertino, J R

“…No effective systemic salvage therapy exists for patients with advanced colorectal cancer who progress after receiving bolus fluorouracil (FU) and leucovorin…”
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Phase II Trial of Docetaxel (Taxotere®) for Untreated Advanced Colorectal Carcinoma by Clark, Torey B., Kemeny, Nancy E., Conti, John A., Huang, Ying, Andre, A. McKenzie, Stockman, Jennifer

“…The antimicrotubule agent docetaxel (Taxotere®), a semisynthetic taxoid, has demonstrated antitumor activity against colorectal cancer cell lines in vitro, and…”
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Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update by Kemeny, N, Seiter, K, Conti, J A, Cohen, A, Bertino, J R, Sigurdson, E R, Botet, J, Chapman, D, Mazumdar, M, Budd, A J

“…We studied three new dose schedules of hepatic arterial infusion of floxuridine (FUDR) and leucovorin and update survival analysis of a previously reported…”
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