Search Results - "Conti, Claudio J."

Assessment of the risk and characterization of non-melanoma skin cancer in Kindler syndrome: study of a series of 91 patients by Guerrero-Aspizua, Sara, Conti, Claudio J, Escamez, Maria Jose, Castiglia, Daniele, Zambruno, Giovanna, Youssefian, Leila, Vahidnezhad, Hassan, Requena, Luis, Itin, Peter, Tadini, Gianluca, Yordanova, Ivelina, Martin, Ludovic, Uitto, Jouni, Has, Cristina, Del Rio, Marcela

“…Kindler Syndrome (KS) is a rare genodermatosis characterized by skin fragility, skin atrophy, premature aging and poikiloderma. It is caused by mutations in…”
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Humanization of Tumor Stroma by Tissue Engineering as a Tool to Improve Squamous Cell Carcinoma Xenograft by Guerrero-Aspizua, Sara, González-Masa, Andrea, Conti, Claudio J, García, Marta, Chacón-Solano, Esteban, Larcher, Fernando, Del Río, Marcela

“…The role of stroma is fundamental in the development and behavior of epithelial tumors. In this regard, limited growth of squamous cell carcinomas (SCC) or…”
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Early Dietary Exposures Epigenetically Program Mammary Cancer Susceptibility through Igf1-Mediated Expansion of the Mammary Stem Cell Compartment by Zheng, Yuanning, Luo, Linjie, Lambertz, Isabel U, Conti, Claudio J, Fuchs-Young, Robin

“…Diet is a critical environmental factor affecting breast cancer risk, and recent evidence shows that dietary exposures during early development can affect…”
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The enhancing effects of obesity on mammary tumor growth and Akt/mTOR pathway activation persist after weight loss and are reversed by RAD001 by De Angel, Rebecca E., Conti, Claudio J., Wheatley, Karrie E., Brenner, Andrew J., Otto, Glen, deGraffenried, Linda A., Hursting, Stephen D.

“…The prevalence of obesity, an established risk and progression factor for postmenopausal breast cancer, remains high in US women. Activation of Akt/mammalian…”
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Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions by Benavides, Fernando, Blando, Jorge, Perez, Carlos J., Garg, Rachana, Conti, Claudio J., DiGiovanni, John, Kazanietz, Marcelo G.

“…It is well established that protein kinase C (PKC) isozymes play distinctive roles in mitogenic and survival signaling as well as in cancer progression. PKCe,…”
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Progressive Metaplastic and Dysplastic Changes in Mouse Pancreas Induced by Cyclooxygenase-2 Overexpression by Colby, Jennifer K.L., Klein, Russell D., McArthur, Mark J., Conti, Claudio J., Kiguchi, Kaoru, Kawamoto, Toru, Riggs, Penny K., Pavone, Amy I., Sawicki, Janet, Fischer, Susan M.

“…Cyclooxygenase-2 (COX-2) overexpression is an established factor linking chronic inflammation with metaplastic and neoplastic change in various tissues. We…”
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Interaction between Genetic Susceptibility and Early-Life Environmental Exposure Determines Tumor-Suppressor-Gene Penetrance by Cook, Jennifer D., Davis, Barbara J., Cai, Sheng-Li, Barrett, J. Carl, Conti, Claudio J., Walker, Cheryl Lyn, Wogan, Gerald N.

“…Gene-environment interactions are important determinants of cancer risk. Traditionally, gene-environment interactions are thought to contribute to…”
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WWOX hypomorphic mice display a higher incidence of B-cell lymphomas and develop testicular atrophy by Ludes-Meyers, John H., Kil, Hyunsuk, Nuñez, Maria I., Conti, Claudio J., Parker-Thornburg, Jan, Bedford, Mark T., Aldaz, C. Marcelo

“…WWOX is a putative tumor suppressor gene encoded within common chromosomal fragile site region FRA16D, in chromosome band 16q23. Multiple studies have…”
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Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes by Perez, Carlos J, Jaubert, Jean, Guénet, Jean-Louis, Barnhart, Kirstin F, Ross-Inta, Catherine M, Quintanilla, Vicente C, Aubin, Isabelle, Brandon, Jimi L, Otto, Nancy W, DiGiovanni, John, Gimenez-Conti, Irma, Giulivi, Cecilia, Kusewitt, Donna F, Conti, Claudio J, Benavides, Fernando

“…Citrullinemia type I (CTLN1, OMIM# 215700) is an inherited urea cycle disorder that is caused by an argininosuccinate synthetase (ASS) enzyme deficiency. In…”
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Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues by Miliani de Marval, Paula L., Macias, Everardo, Rounbehler, Robert, Sicinski, Piotr, Kiyokawa, Hiroaki, Johnson, David G., Conti, Claudio J., Rodriguez-Puebla, Marcelo L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development by LARCHER, F, MURILLAS, R, BOLONTRADE, M, CONTI, C. J, JORCANO, J. L

“…Upregulation of keratinocyte-derived VEGF-A expression has recently been established in non-neoplastic processes of skin such as wound healing, blistering…”
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The importance of immunity in the development of reliable animal models for psoriasis and atopic dermatitis by Guerrero‐Aspizua, Sara, Carretero, Marta, Conti, Claudio J, Del Río, Marcela

“…Psoriasis (PS) and atopic dermatitis (AD) are common inflammatory skin diseases characterized by an imbalance in specific T‐cell subsets, resulting in a…”
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Molecular mechanisms of protein kinase C-induced apoptosis in prostate cancer cells by Gonzalez-Guerrico, Anatilde M, Meshki, John, Xiao, Liqing, Benavides, Fernando, Conti, Claudio J, Kazanietz, Marcelo G

“…Protein kinase C (PKC) isozymes, a family of serine-threonine kinases, are important regulators of cell proliferation and malignant transformation. Phorbol…”
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Dynamic role of the codon 72 p53 single-nucleotide polymorphism in mammary tumorigenesis in a humanized mouse model by Gunaratna, Ramesh T., Santos, Andres, Luo, Linjie, Nagi, Chandandeep, Lambertz, Isabel, Spier, Madison, Conti, Claudio J., Fuchs-Young, Robin S.

“…Female breast cancer (BrCa) is the most common noncutaneous cancer among women in the United States. Human epidemiological studies reveal that a p53…”
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High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC by Sands, Arthur T, Abuin, Alejandro, Sanchez, Ana, Conti, Claudio J, Bradley, Allan

“…Compromise of genetic information by mutation may result in the dysregulation of cellular growth control and subsequent tumour formation. Xeroderma pigmentosum…”
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Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8‐expressing transgenic mice by Casanova, M. Llanos, Bravo, Ana, Martínez‐Palacio, Jesús, Jesús Fernández‐Aceñero, M., Villanueva, Concepción, Larcher, Fernando, Conti, Claudio J., Jorcano, José L.

“…ABSTRACT Keratins K8 and K18 are the major components of the intermediate filament cytoskeleton of simple epithelia. Increased levels of these keratins have…”
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ARF Differentially Modulates Apoptosis Induced by E2F1 and Myc by Russell, Jamie L., Powers, John T., Rounbehler, Robert J., Rogers, Pamela M., Conti, Claudio J., Johnson, David G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b) by Rojas, Paola, Benavides, Fernando, Blando, Jorge, Perez, Carlos, Cardenas, Kim, Richie, Ellen, Knudsen, Erik S., Johnson, David G., Senderowicz, Adrian M., Rodriguez-Puebla, Marcelo L., Conti, Claudio J.

“…Cyclin D1b is an alternative transcript of the cyclin D1 gene (CCND1) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism…”
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Transcriptional Regulation of Estrogen Receptor-α by p53 in Human Breast Cancer Cells by HARKEY SHIRLEY, Stephanie, RUNDHAUG, Joyce E, JIE TIAN, CULLINAN-AMMANN, Noirin, LAMBERTZ, Isabel, CONTI, Claudio J, FUCHS-YOUNG, Robin

“…Estrogen receptor alpha (ER) and p53 are critical prognostic indicators in breast cancer. Loss of functional p53 is correlated with poor prognosis, ER…”
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Early Exposure to a High Fat/High Sugar Diet Increases the Mammary Stem Cell Compartment and Mammary Tumor Risk in Female Mice by Lambertz, Isabel U, Luo, Linjie, Berton, Thomas R, Schwartz, Scott L, Hursting, Stephen D, Conti, Claudio J, Fuchs-Young, Robin

“…Obesity and alterations in metabolic programming from early diet exposures can affect the propensity to disease in later life. Through dietary manipulation,…”
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