Search Results - "Conti, Anna"

Genetics and Molecular Basis of Congenital Heart Defects in Down Syndrome: Role of Extracellular Matrix Regulation by Mollo, Nunzia, Scognamiglio, Roberta, Conti, Anna, Paladino, Simona, Nitsch, Lucio, Izzo, Antonella

“…Down syndrome (DS), a complex disorder that is caused by the trisomy of chromosome 21 (Hsa21), is a major cause of congenital heart defects (CHD)…”
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Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets by Izzo, Antonella, Mollo, Nunzia, Nitti, Maria, Paladino, Simona, Calì, Gaetano, Genesio, Rita, Bonfiglio, Ferdinando, Cicatiello, Rita, Barbato, Maria, Sarnataro, Viviana, Conti, Anna, Nitsch, Lucio

“…Trisomy of chromosome 21 (TS21) is the most common autosomal aneuploidy compatible with postnatal survival with a prevalence of 1 in 700 newborns. Its…”
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Targeting Mitochondrial Network Architecture in Down Syndrome and Aging by Mollo, Nunzia, Cicatiello, Rita, Aurilia, Miriam, Scognamiglio, Roberta, Genesio, Rita, Charalambous, Maria, Paladino, Simona, Conti, Anna, Nitsch, Lucio, Izzo, Antonella

“…Mitochondria are organelles that mainly control energy conversion in the cell. In addition, they also participate in many relevant activities, such as the…”
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The hand that has forgotten its cunning-Lessons from musicians' hand dystonia by Conti, Anna M., Pullman, Seth, Frucht, Steven J.

“…Focal task‐specific dystonia of the musicians' hand (FTSDmh) is an occupational movement disorder that affects instrumental musicians and often derails…”
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NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome by Izzo, Antonella, Manco, Rosanna, Bonfiglio, Ferdinando, Calì, Gaetano, De Cristofaro, Tiziana, Patergnani, Simone, Cicatiello, Rita, Scrima, Rosella, Zannini, Mariastella, Pinton, Paolo, Conti, Anna, Nitsch, Lucio

“…Mitochondrial dysfunction, which is consistently observed in Down syndrome (DS) cells and tissues, might contribute to the severity of the DS phenotype. Our…”
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Overexpression of the Hsa21 Transcription Factor RUNX1 Modulates the Extracellular Matrix in Trisomy 21 Cells by Mollo, Nunzia, Aurilia, Miriam, Scognamiglio, Roberta, Zerillo, Lucrezia, Cicatiello, Rita, Bonfiglio, Ferdinando, Pagano, Pasqualina, Paladino, Simona, Conti, Anna, Nitsch, Lucio, Izzo, Antonella

“…Down syndrome is a neurodevelopmental disorder frequently characterized by other developmental defects, such as congenital heart disease. Analysis of gene…”
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Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression by De Rosa, Laura, Fasano, Dominga, Zerillo, Lucrezia, Valente, Valeria, Izzo, Antonella, Mollo, Nunzia, Amodio, Giuseppina, Polishchuk, Elena, Polishchuk, Roman, Melone, Mariarosa Anna Beatrice, Criscuolo, Chiara, Conti, Anna, Nitsch, Lucio, Remondelli, Paolo, Pierantoni, Giovanna Maria, Paladino, Simona

“…Endosomal trafficking is essential for cellular homeostasis. At the crossroads of distinct intracellular pathways, the endolysosomal system is crucial to…”
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Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells by Mollo, Nunzia, Nitti, Maria, Zerillo, Lucrezia, Faicchia, Deriggio, Micillo, Teresa, Accarino, Rossella, Secondo, Agnese, Petrozziello, Tiziana, Calì, Gaetano, Cicatiello, Rita, Bonfiglio, Ferdinando, Sarnataro, Viviana, Genesio, Rita, Izzo, Antonella, Pinton, Paolo, Matarese, Giuseppe, Paladino, Simona, Conti, Anna, Nitsch, Lucio

“…Mitochondrial dysfunction plays a primary role in neurodevelopmental anomalies and neurodegeneration of Down syndrome (DS) subjects. For this reason, targeting…”
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Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation by Mollo, Nunzia, Esposito, Matteo, Aurilia, Miriam, Scognamiglio, Roberta, Accarino, Rossella, Bonfiglio, Ferdinando, Cicatiello, Rita, Charalambous, Maria, Procaccini, Claudio, Micillo, Teresa, Genesio, Rita, Calì, Gaetano, Secondo, Agnese, Paladino, Simona, Matarese, Giuseppe, De Vita, Gabriella, Conti, Anna, Nitsch, Lucio, Izzo, Antonella

“…Background: The presence of mitochondrial alterations in Down syndrome suggests that it might affect neuronal differentiation. We established a model of…”
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Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy by Conti, Anna, Fabbrini, Floriana, D'Agostino, Paola, Negri, Rosa, Greco, Dario, Genesio, Rita, D'Armiento, Maria, Olla, Carlo, Paladini, Dario, Zannini, Mariastella, Nitsch, Lucio

“…The Down syndrome phenotype has been attributed to overexpression of chromosome 21 (Hsa21) genes. However, the expression profile of Hsa21 genes in trisomic…”
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Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis by Di Palma, Tina, Conti, Anna, de Cristofaro, Tiziana, Scala, Serena, Nitsch, Lucio, Zannini, Mariastella

“…The differentiation program of thyroid follicular cells (TFCs), by far the most abundant cell population of the thyroid gland, relies on the interplay between…”
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Corrigendum: Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells by Mollo, Nunzia, Nitti, Maria, Zerillo, Lucrezia, Faicchia, Deriggio, Micillo, Teresa, Accarino, Rossella, Secondo, Agnese, Petrozziello, Tiziana, Calì, Gaetano, Cicatiello, Rita, Bonfiglio, Ferdinando, Sarnataro, Viviana, Genesio, Rita, Izzo, Antonella, Pinton, Paolo, Matarese, Giuseppe, Paladino, Simona, Conti, Anna, Nitsch, Lucio

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Chromosomal Microarray Analysis versus Karyotyping in Fetuses with Increased Nuchal Translucency by Cicatiello, Rita, Pignataro, Piero, Izzo, Antonella, Mollo, Nunzia, Pezone, Lucia, Maruotti, Giuseppe Maria, Sarno, Laura, Sglavo, Gabriella, Conti, Anna, Genesio, Rita, Nitsch, Lucio

“…We have carried out a retrospective study of chromosome anomalies associated with increased nuchal translucency (NT) in order to compare yield rates of…”
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Architectural Mapping: Proiectura - Lovere, la città illuminata by Moretti Conti, Anna

“…Una riflessione e un racconto fotografico sul progetto Proiectura-Lovere la città illuminata, un architectural mapping realizzato nel maggio 2023 nella…”
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Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses by Conti, Anna, Nitsch, Lucio, Zannini, Mariastella, Martino, Marco De, Mollo, Nunzia, Cicatiello, Rita, Bonfiglio, Ferdinando, Cristofaro, Tiziana de, Manco, Rosanna, Izzo, Antonella, Genesio, Rita

“…Dosage-dependent upregulation of most of chromosome 21 (Hsa21) genes has been demonstrated in heart tissues of fetuses with Down syndrome (DS). Also miRNAs…”
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The neural progenitor-restricted isoform of the MARK4 gene in 19q13.2 is upregulated in human gliomas and overexpressed in a subset of glioblastoma cell lines by BEGHINI, Alessandro, MAGNANI, Ivana, LARIZZA, Lidia, ROVERSI, Gaia, PIEPOLI, Tiziana, DI TERLIZZI, Simona, MORONI, Ramona F, POLLO, Bianca, FUHRMAN CONTI, Anna M, COWELL, John K, FINOCCHIARO, Gaetano

“…Alterations of 19q13 are frequently observed in glial neoplasms, suggesting that this region harbors at least one gene involved in gliomagenesis. Following our…”
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Exploring Burial and Dietary Patterns at the Copper Age Necropolis of Selvicciola (Viterbo, Italy): New Perspectives from 14C and Stable Isotope Data by Maria Rosa di Cicco, Altieri, Simona, Mantile, Noemi, Petitti, Patrizia, Persiani, Carlo, Conti, Anna Maria, Allegrezza, Luciana, Cavazzuti, Claudio, Lubritto, Carmine

“…The Selvicciola necropolis is a large burial site dated to the Copper Age, located on the mid-Tyrrhenian side of Central Italy, in the Fiora river valley…”
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Wide gene expression profiling of ischemia‐reperfusion injury in human liver transplantation by Conti, Anna, Scala, Simona, D'Agostino, Paola, Alimenti, Elena, Morelli, Daniele, Andria, Barbara, Tammaro, Angela, Attanasio, Chiara, Ragione, Floriana Della, Scuderi, Vincenzo, Fabbrini, Floriana, D'Esposito, Maurizio, Di Florio, Ernesto, Nitsch, Lucio, Calise, Fulvio, Faiella, Antonio

“…Ischemia‐reperfusion injury (IRI) causes up to 10% of early liver failures in humans and can lead to a higher incidence of acute and chronic rejection. So far,…”
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Variegated silencing through epigenetic modifications of a large Xq region in a case of balanced X;2 translocation with Incontinentia Pigmenti-like phenotype by Genesio, Rita, Melis, Daniela, Gatto, Sole, Izzo, Antonella, Ronga, Valentina, Cappuccio, Gerarda, Lanzo, Ambra, Andria, Generoso, D'Esposito, Maurizio, Matarazzo, Maria R., Conti, Anna, Nitsch, Lucio

“…Molecular mechanisms underlying aberrant phenotypes in balanced X;autosome translocations are scarcely understood. We report the case of a de novo reciprocal…”
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Suppression of neurite outgrowth by high-dose nerve growth factor is independent of functional p75NTR receptors by Conti, Anna M., Brimijoin, Stephen, Miller, Laurence J., Windebank, Anthony J.

“…We have previously demonstrated that high concentrations of nerve growth factor suppress neurite outgrowth from sensory neurons. Inhibition could be mediated…”
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