Search Results - "Contasta, Ida"

A gender-related action of IFNbeta-therapy was found in multiple sclerosis by Contasta, Ida, Totaro, Rocco, Pellegrini, Patrizia, Del Beato, Tiziana, Carolei, Antonio, Berghella, Anna Maria

“…Understanding how sexual dimorphism affects the physiological and pathological responses of the immune system is of considerable clinical importance and could…”
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The Role of Gender-specific Cytokine Pathways as Drug Targets and Gender- specific Biomarkers in Personalized Cancer Therapy by Berghella, Anna Maria, Contasta, Ida, Lattanzio, Roberto, Di Gregorio, Giancarlo, Campitelli, Irma, Silvino, Marino, Liberatore, Luigi Liborio, Navarra, Luca, Caterino, Giampaolo, Mongelli, Antonio, Vittorini, Vincenzo, Basta, Matteo, Domenicucci, Mauro, Antonucci, Nunzia, Del Beato, Tiziana, Secinaro, Enzo, Ciccone, Fabiana, Pellegrini, Patrizia

“…The definition of personalized treatments in tumor disease could lead to an improvement of the therapeutic success rate. Therefore, biomarkers are urgently…”
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The discovery of how gender influences age immunological mechanisms in health and disease, and the identification of ageing gender-specific biomarkers, could lead to specifically tailored treatment and ultimately improve therapeutic success rates by Berghella, Anna Maria, Contasta, Ida, Del Beato, Tiziana, Pellegrini, Patrizia

“…The control of human health and diseases in the elderly population is becoming a challenge, since mean age and life expectation are progressively increasing as…”
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Gender-Specific Cytokine Pathways, Targets, and Biomarkers for the Switch from Health to Adenoma and Colorectal Cancer by Pellegrini, Patrizia, Contasta, Ida, Del Beato, Tiziana, Ciccone, Fabiana, Berghella, Anna Maria

“…Studies focusing on gender have shown that differences exist in how the immune system responds to disease and therapy. Understanding how gender influences…”
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The potential role of thioredoxin 1 and CD30 systems as multiple pathway targets and biomarkers in tumor therapy by Berghella, Anna Maria, Pellegrini, Patrizia, Del Beato, Tiziana, Ciccone, Fabiana, Contasta, Ida

“…Our progress in understanding pathological disease mechanisms has led to the identification of biomarkers that have had a considerable impact on clinical…”
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Ageing gender-specific "Biomarkers of Homeostasis", to protect ourselves against the diseases of the old age by Berghella, Anna Maria, Contasta, Ida, Marulli, Giuseppe, D'Innocenzo, Carlo, Garofalo, Ferdinando, Gizzi, Francesca, Bartolomucci, Marco, Laglia, Giacomo, Valeri, Marisa, Gizzi, Mario, Friscioni, Mauro, Barone, Mario, Del Beato, Tiziana, Secinaro, Enzo, Pellegrini, Patrizia

“…Low-grade inflammatory state causes the development of the principal chronic-degenerative pathologies related with ageing. Consequently, it is required a…”
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CD30 antigen: not a physiological marker for TH2 cells but an important costimulator molecule in the regulation of the balance between TH1/TH2 response by Pellegrini, Patrizia, Berghella, Anna Maria, Contasta, Ida, Adorno, Domenico

“…Understanding the physiological role of CD30 would be an important step forward in transplants because CD30 + T cells can be induced by alloantigens even in…”
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Gender-Specific Cytokine Pathways, Targets, and Biomarkers for the Switch from Health to Adenoma and Colorectal Cancer by Ciccone, Fabiana, Del Beato, Tiziana, Contasta, Ida, Pellegrini, Patrizia, Berghella, Anna Maria

“…Studies focusing on gender have shown that differences exist in how the immune system responds to disease and therapy. Understanding how gender influences…”
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The study of a patient's immune system may prove to be a useful noninvasive tool for stage classification in colon cancer by Pellegrini, Patrizia, Berghella, Anna Maria, Contasta, Ida, Del Beato, Tiziana, Adorno, Domenico

“…Therapy, and, therefore, prognosis, is strictly related to cancer stage, and hence, screening tests that can contribute to the early classification of disease…”
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Are immunological mechanisms involved in colon cancer and are they possible markers for biotherapy improvement? by Berghella, Anna Maria, Contasta, Ida, Pellegrini, Patrizia, Del Beato, Tiziana, Adorno, Domenico

“…This paper focuses on our data on colon cancer patients. Our overall results lead us to believe that the suppressive effect of specific cytokines in colon…”
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Passage from normal mucosa to adenoma and colon cancer: alteration of normal sCD30 mechanisms regulating TH1/TH2 cell functions by Contasta, Ida, Berghella, Anna Maria, Pellegrini, Patrizia, Adorno, Domenico

“…The pathogenesis of cancer is currently under intensive investigation to identify reliable prognostic indices for the early detection of disease. Adenomas have…”
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Colon cancer and gene alterations: their immunological implications and suggestions for prognostic indices and improvements in biotherapy by Contasta, Ida, Pellegrini, Patrizia, Berghella, Anna Maria, Del Beato, Tiziana, Adorno, Domenico

“…Studies have shown that changes occur in c-Ki-ras, p53, and Bcl2 gene structure and function during the various stages of human colon carcinogenesis…”
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IFNbeta-1a treatment and reestablishment of Th1 regulation in MS patients: dose effects by Pellegrini, Patrizia, Totaro, Rocco, Contasta, Ida, Berghella, Anna Maria, Russo, Tomassina, Carolei, Antonio, Adorno, Domenico

“…The authors evaluated the relationships between clinical and pharmacologic parameters and the Th1/Th2/Th3 cytokine network in patients with relapsing-remitting…”
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Simultaneous measurement of soluble carcinoembryonic antigen and the tissue inhibitor of metalloproteinase TIMP1 serum levels for use as markers of pre-invasive to invasive colorectal cancer by PELLEGRINI, P, CONTASTA, I, BERGHELLA, A. M, GARGANO, E, MAMMARELLA, C, ADORNO, D

“…Matrix metalloproteinases (MMP) are members of a multigene family of zinc-dependent enzymes involved in the degradation of extracellular matrix components…”
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Immunological study of IFNbeta-1a-treated and untreated multiple sclerosis patients: clarifying IFNbeta mechanisms and establishing specific dendritic cell immunotherapy by Berghella, Anna Maria, Totaro, Rocco, Pellegrini, Patrizia, Contasta, Ida, Russo, Tomassina, Carolei, Antonio, Adorno, Domenico

“…A comparative immunological evaluation of multiple sclerosis (MS) patients receiving IFNbeta treatment and patients who are not receiving treatment may help…”
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CD30 antigen and multiple sclerosis: CD30, an important costimulatory molecule and marker of a regulatory subpopulation of dendritic cells, is involved in the maintenance of the physiological balance between TH1/TH2 immune responses and tolerance. The role of IFNbeta-1a in the treatment of multiple sclerosis by Pellegrini, Patrizia, Totaro, Rocco, Contasta, Ida, Berghella, Anna Maria, Carolei, Antonio, Adorno, Domenico

“…The immunological effect of CD30 on dendritic cells (DCs) was examined in a comparative study of patients with relapsing-remitting multiple sclerosis (RRMS)…”
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Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer by Berghella, Anna Maria, Contasta, Ida, Pellegrini, Patrizia, Del Beato, Tiziana, Adorno, Domenico

“…In cancer, the extent to which the disease has spread is probably the most important factor in determining patient prognosis. Hence practical and non-invasive…”
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IFN??-1a Treatment and Reestablishment of Th1 Regulation in MS Patients: Dose Effects by Pellegrini, Patrizia, Totaro, Rocco, Contasta, Ida, Berghella, Anna Maria, Russo, Tomassina, Carolei, Antonio, Adorno, Domenico

“…The authors evaluated the relationships between clinical and pharmacologic parameters and the Th1/Th2/Th3 cytokine network in patients with relapsing-remitting…”
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Cell cycle control in cellular homeostasis during the immune response: interactions between TH1, TH2 cytokines, and Bcl2 and p53 molecules by Contasta, I, Pellegrini, P, Berghella, A M, Adorno, D

“…Cytokine regulation of lymphocyte survival may play an important role in the control of the cell cycle during the immune response both in health and disease…”
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Relationships between the activity of MMP1/TIMP1 enzymes and the TH1/TH2 cytokine network by Contasta, I, Berghella, A M, Pellegrini, P, Del Beato, T, Casciani, C A, Adorno, D

“…The evaluation of the balance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) would appear to be important in…”
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