Search Results - "Contarelli, Serena"

Targeting KRAS: The Elephant in the Room of Epithelial Cancers by Merz, Valeria, Gaule, Marina, Zecchetto, Camilla, Cavaliere, Alessandro, Casalino, Simona, Pesoni, Camilla, Contarelli, Serena, Sabbadini, Fabio, Bertolini, Monica, Mangiameli, Domenico, Milella, Michele, Fedele, Vita, Melisi, Davide

“…Mutations of the proto-oncogene KRAS are the most frequent gain-of-function alterations found in cancer. KRAS is mutated in about 30% of all human tumors, but…”
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Muscle and Systemic Molecular Responses to a Single Flywheel Based Iso-Inertial Training Session in Resistance-Trained Men by Annibalini, Giosuè, Contarelli, Serena, Lucertini, Francesco, Guescini, Michele, Maggio, Serena, Ceccaroli, Paola, Gervasi, Marco, Ferri Marini, Carlo, Fardetti, Francesco, Grassi, Eugenio, Stocchi, Vilberto, Barbieri, Elena, Benelli, Piero

“…Growing evidence points to the effectiveness of flywheel (FW) based iso-inertial resistance training in improving physical performance capacities. However,…”
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Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics by Minnock, Dean, Annibalini, Giosuè, Le Roux, Carel W., Contarelli, Serena, Krause, Mauricio, Saltarelli, Roberta, Valli, Giacomo, Stocchi, Vilberto, Barbieri, Elena, De Vito, Giuseppe

“…Purpose To compare the effect of high-intensity aerobic (AER), resistance (RES), and combined (COMB: RES + AER) exercise, on interstitial glucose (IG)…”
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A phase II trial of the FGFR inhibitor pemigatinib in patients with metastatic esophageal–gastric junction/gastric cancer trastuzumab resistant: the FiGhTeR trial by Merz, Valeria, Zecchetto, Camilla, Simionato, Francesca, Cavaliere, Alessandro, Casalino, Simona, Pavarana, Michele, Giacopuzzi, Simone, Bencivenga, Maria, Tomezzoli, Anna, Santoro, Raffaela, Fedele, Vita, Contarelli, Serena, Rossi, Irene, Giacomazzi, Serena, Pasquato, Martina, Piazzola, Cristiana, Milleri, Stefano, de Manzoni, Giovanni, Melisi, Davide

“…Background: Prognosis of patients affected by metastatic esophageal–gastric junction (EGJ) or gastric cancer (GC) remains dismal. Trastuzumab, an anti-HER2…”
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Novel Biomarkers for Prediction of Response to Preoperative Systemic Therapies in Gastric Cancer by Cavaliere, Alessandro, Merz, Valeria, Casalino, Simona, Zecchetto, Camilla, Simionato, Francesca, Salt, Hayley Louise, Contarelli, Serena, Santoro, Raffaela, Melisi, Davide

“…Preoperative chemo- and radiotherapeutic strategies followed by surgery are currently a standard approach for treating locally advanced gastric and…”
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Novel Biomarkers for Prediction of Response to Preoperative Systemic Therapies in Gastric Cancer by Cavaliere, Alessandro, Merz, Valeria, Casalino, Simona, Zecchetto, Camilla, Simionato, Francesca, Salt, Hayley Louise, Contarelli, Serena, Santoro, Raffaela, Melisi, Davide

“…Preoperative chemo- and radiotherapeutic strategies followed by surgery are currently a standard approach for treating locally advanced gastric and…”
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HOX Genes Family and Cancer: A Novel Role for Homeobox B9 in the Resistance to Anti-Angiogenic Therapies by Contarelli, Serena, Fedele, Vita, Melisi, Davide

“…Angiogenesis is one of the hallmarks of cancer, and the inhibition of pro-angiogenic factors and or their receptors has become a primary strategy for cancer…”
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The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people by Krause, Mauricio, Crognale, Domenico, Cogan, Karl, Contarelli, Serena, Egan, Brendan, Newsholme, Philip, De Vito, Giuseppe

“…This investigation sought to determine the effects of twelve weeks of resistance exercise training in addition to protein supplementation on body composition,…”
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The Multifaceted Role of TGF-β in Gastrointestinal Tumors by Sabbadini, Fabio, Bertolini, Monica, De Matteis, Serena, Mangiameli, Domenico, Contarelli, Serena, Pietrobono, Silvia, Melisi, Davide

“…Transforming growth factor-beta (TGF-β) is a secreted cytokine that signals via serine/threonine kinase receptors and SMAD effectors. Although TGF-β acts as a…”
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Clinical Response to Futibatinib in Patients with High-Level FGFR2-Amplified Advanced Gastric Cancer: Two Case Reports by Quinzii, Alberto, Zecchetto, Camilla, Casalino, Simona, Gaule, Marina, Pesoni, Camilla, Merz, Valeria, Contarelli, Serena, Pietrobono, Silvia, Benhadji, Karim A., Melisi, Davide

“…Genomic alterations responsible for a ligand-independent activation of these tyrosine kinases receptors, including activating point mutations, amplifications,…”
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The intrinsically disordered E-domains regulate the IGF-1 prohormones stability, subcellular localisation and secretion by Annibalini, Giosuè, Contarelli, Serena, De Santi, Mauro, Saltarelli, Roberta, Di Patria, Laura, Guescini, Michele, Villarini, Anna, Brandi, Giorgio, Stocchi, Vilberto, Barbieri, Elena

“…Insulin-like growth factor-1 (IGF-1) is synthesised as a prohormone (proIGF-1) requiring enzymatic activity to yield the mature IGF-1. Three proIGF-1s are…”
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Exceptional Clinical Response to Alectinib in Pancreatic Acinar Cell Carcinoma With a Novel ALK-KANK4 Gene Fusion by Gaule, Marina, Pesoni, Camilla, Quinzii, Alberto, Zecchetto, Camilla, Casalino, Simona, Merz, Valeria, Contarelli, Serena, Pietrobono, Silvia, Vissio, Elena, Molinaro, Luca, Manzin, Enrica, Volpatto, Roberta, Vellani, Giorgio, Melisi, Davide

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Abstract 1064: Targeting stromal autotaxin synergizes with TGF beta inhibition in pancreatic cancer by Sabbadini, Fabio, Bertolini, Monica, Mangiameli, Domenico, Contarelli, Serena, Johnson, Zoë, Lahn, Michael M., Pietrobono, Silvia, Melisi, Davide

“…The TGFβ receptor inhibitor galunisertib (GAL) has been demonstrated as an effective strategy for the treatment of pancreatic cancer (PC) patients, in part…”
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Human IGF1 pro-forms induce breast cancer cell proliferation via the IGF1 receptor by De Santi, Mauro, Annibalini, Giosuè, Barbieri, Elena, Villarini, Anna, Vallorani, Luciana, Contarelli, Serena, Berrino, Franco, Stocchi, Vilberto, Brandi, Giorgio

“…Background IGF1 is a key regulator of tissue growth and development and has been implicated in the initiation and progression of various cancers, including…”
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MIR retroposon exonization promotes evolutionary variability and generates species-specific expression of IGF-1 splice variants by Annibalini, Giosuè, Bielli, Pamela, De Santi, Mauro, Agostini, Deborah, Guescini, Michele, Sisti, Davide, Contarelli, Serena, Brandi, Giorgio, Villarini, Anna, Stocchi, Vilberto, Sette, Claudio, Barbieri, Elena

“…Insulin-like growth factor (IGF) -1 is a pleiotropic hormone exerting mitogenic and anti-apoptotic effects. Inclusion or exclusion of exon 5 into the IGF-1…”
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Clinical Response to Futibatinib in Patients with High-Level FGFR2-Amplified Advanced Gastric Cancer: Two Case Reports by Quinzii, Alberto, Zecchetto, Camilla, Casalino, Simona, Gaule, Marina, Pesoni, Camilla, Merz, Valeria, Contarelli, Serena, Pietrobono, Silvia, Benhadji, Karim A, Melisi, Davide

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