Search Results - "Contaldi, Elena"
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The Immune System as a Therapeutic Target for Old and New Drugs in Parkinson's Disease
Published in CNS & neurological disorders drug targets (2023)“…Parkinson's disease (PD) is a common neurodegenerative disease characterized by loss of dopaminergic neurons and intraneuronal accumulation of protein…”
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The Impact of SNCA Variations and Its Product Alpha-Synuclein on Non-Motor Features of Parkinson’s Disease
Published in Life (Basel, Switzerland) (09-08-2021)“…Parkinson’s disease (PD) is a common and progressive neurodegenerative disease, caused by the loss of dopaminergic neurons in the substantia nigra pars…”
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Motor and non-motor symptom improvement after mRNA-1273 vaccine in a Parkinson’s disease patient
Published in Neurological sciences (01-02-2022)Get full text
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Immune Response Modifications in the Genetic Forms of Parkinson's Disease: What Do We Know?
Published in International journal of molecular sciences (23-03-2022)“…Parkinson's disease (PD) is a common neurodegenerative disease characterized by loss of dopaminergic neurons in the of the midbrain . PD pathophysiology is…”
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Polymorphisms of Dopamine Receptor Genes and Parkinson's Disease: Clinical Relevance and Future Perspectives
Published in International journal of molecular sciences (06-04-2021)“…Parkinson's disease (PD) is a neurodegenerative disease caused by loss of dopaminergic neurons in the midbrain. PD is clinically characterized by a variety of…”
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Telehealth in Neurodegenerative Diseases: Opportunities and Challenges for Patients and Physicians
Published in Brain sciences (13-02-2021)“…Telehealth, by definition, is distributing health-related services while using electronic technologies. This narrative Review describes the technological…”
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The Role of Tau beyond Alzheimer's Disease: A Narrative Review
Published in Biomedicines (24-03-2022)“…Nowadays, there is a need for reliable fluid biomarkers to improve differential diagnosis, prognosis, and the prediction of treatment response, particularly in…”
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The PROB-PD trial: a pilot, randomised, placebo-controlled study protocol to evaluate the feasibility and potential efficacy of probiotics in modulating peripheral immunity in subjects with Parkinson's disease
Published in Pilot and feasibility studies (08-05-2023)“…Parkinson's disease (PD) is a common neurodegenerative disease. No disease-modifying treatment is available, and therapy is symptomatic. The histopathologic…”
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Potential protective role of ACE-inhibitors and AT1 receptor blockers against levodopa-induced dyskinesias: a retrospective case-control study
Published in Neural regeneration research (01-12-2021)“…Growing evidence has highlighted that angiotensin-converting enzyme (ACE)-inhibitors (ACEi)/AT1 receptor blockers (ARBs) may influence the complex interplay…”
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Multiplex Matrix Metalloproteinases Analysis in the Cerebrospinal Fluid Reveals Potential Specific Patterns in Multiple Sclerosis Patients
Published in Frontiers in neurology (18-12-2018)“…Matrix metalloproteinases (MMPs) are pleiotropic enzymes involved in extracellular protein degradation and turnover. MMPs are implicated in the pathogenesis of…”
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Clinical correlates of “pure” essential tremor: the TITAN study
Published in Frontiers in neurology (23-08-2023)“…Background To date, there are no large studies delineating the clinical correlates of “pure” essential tremor (ET) according to its new definition. Methods…”
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Relationship between [123I]FP-CIT SPECT data and peripheral CD4 + T cell profile in newly-diagnosed drug-naïve Parkinson’s disease patients
Published in Journal of neurology (01-05-2023)“…Background Dysregulation of the CD4 + T cell compartment occurs in Parkinson’s Disease (PD). Nonetheless, the exact relationship with dopamine transporter…”
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Relationship between circulating CD4+ T lymphocytes and cognitive impairment in patients with Parkinson’s disease
Published in Brain, behavior, and immunity (01-10-2020)“…•Immune system may play a role in the pathophysiology of cognitive decline in Parkinson’s disease (PD).•PD patients with cognitive decline may display a…”
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Disease mechanisms as subtypes: Immune dysfunction in Parkinson's disease
Published in Handbook of clinical neurology (2023)“…In recent years, the contraposition between inflammatory and neurodegenerative processes has been increasingly challenged. Inflammation has been emphasized as…”
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Striatal dopamine transporter imaging in Parkinson’s disease drug-naïve patients: focus on sexual dysfunction
Published in Neurological sciences (01-08-2022)“…Introduction Dopamine is involved in sexual behavior, but dopaminergic imaging studies establishing the relationship between nigrostriatal dopaminergic…”
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Parkinson's disease and chronic inflammatory demyelinating polyneuropathy: Broadening the clinical spectrum of VCP mutations
Published in Parkinsonism & related disorders (01-01-2024)Get full text
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Lymphocyte Count and Neutrophil-to-Lymphocyte Ratio Are Associated with Mild Cognitive Impairment in Parkinson’s Disease: A Single-Center Longitudinal Study
Published in Journal of clinical medicine (22-09-2022)“…Lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) may represent useful biomarkers of Parkinson’s disease (PD), but their role in PD-related mild…”
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A case of early-onset Parkinson’s disease in a patient with KBG syndrome
Published in Neurological sciences (01-12-2023)Get full text
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Parkinsonism in SCA19/22: Dopamine Transporter Imaging in an Italian Family Harboring a Novel Mutation
Published in Cerebellum (London, England) (01-06-2024)“…Spinocerebellar ataxia (SCA)19/22 is a channelopathy caused by mutations in the KCND3 gene encoding for the voltage-gated potassium channel Kv4.3. In the…”
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