Search Results - "Contadini, Claudia"

SRC Kinase in Glioblastoma: News from an Old Acquaintance by Cirotti, Claudia, Contadini, Claudia, Barilà, Daniela

“…Glioblastoma multiforme (GBM) is one of the most recalcitrant brain tumors characterized by a tumor microenvironment (TME) that strongly supports GBM growth,…”
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Caspase-8: A Novel Target to Overcome Resistance to Chemotherapy in Glioblastoma by Fianco, Giulia, Contadini, Claudia, Ferri, Alessandra, Cirotti, Claudia, Stagni, Venturina, Barilà, Daniela

“…Caspase-8 was originally identified as a central player of programmed cell death triggered by death receptor stimulation. In that context, its activity is…”
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Identification and Biological Characterization of the Pyrazolo[3,4- d ]pyrimidine Derivative SI388 Active as Src Inhibitor by Contadini, Claudia, Cirotti, Claudia, Carbone, Anna, Norouzi, Mehrdad, Cianciusi, Annarita, Crespan, Emmanuele, Perini, Cecilia, Maga, Giovanni, Barilà, Daniela, Musumeci, Francesca, Schenone, Silvia

“…Src is a non-receptor tyrosine kinase (TK) whose involvement in cancer, including glioblastoma (GBM), has been extensively demonstrated. In this context, we…”
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Caspase-8 and Tyrosine Kinases: A Dangerous Liaison in Cancer by Contadini, Claudia, Ferri, Alessandra, Cirotti, Claudia, Stupack, Dwayne, Barilà, Daniela

“…Caspase-8 is a cysteine-aspartic acid protease that has been identified as an initiator caspase that plays an essential role in the extrinsic apoptotic…”
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Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy by Contadini, Claudia, Ferri, Alessandra, Di Martile, Marta, Cirotti, Claudia, Del Bufalo, Donatella, De Nicola, Francesca, Pallocca, Matteo, Fanciulli, Maurizio, Sacco, Francesca, Donninelli, Gloria, Capone, Alessia, Volpe, Elisabetta, Keller, Nadine, Miki, Shunichiro, Kawauchi, Daisuke, Stupack, Dwayne, Furnari, Frank, Barilà, Daniela

“…Caspase-8 is a cysteine protease that plays an essential role in apoptosis. Consistently with its canonical proapoptotic function, cancer cells may genetically…”
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p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway by Contadini, Claudia, Monteonofrio, Laura, Virdia, Ilaria, Prodosmo, Andrea, Valente, Davide, Chessa, Luciana, Musio, Antonio, Fava, Luca L., Rinaldo, Cinzia, Di Rocco, Giuliana, Soddu, Silvia

“…Centrosomal p53 has been described for three decades but its role is still unclear. We previously reported that, in proliferating human cells, p53 transiently…”
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A Triphenylphosphonium-Functionalized Delivery System for an ATM Kinase Inhibitor That Ameliorates Doxorubicin Resistance in Breast Carcinoma Mammospheres by Stagni, Venturina, Kaminari, Archontia, Contadini, Claudia, Barilà, Daniela, Sessa, Rosario Luigi, Sideratou, Zili, Vlahopoulos, Spiros A, Tsiourvas, Dimitris

“…The enzyme ataxia-telangiectasia mutated (ATM) kinase is a pluripotent signaling mediator which activates cellular responses to genotoxic and metabolic stress…”
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NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma by Cirotti, Claudia, Taddei, Irene, Contadini, Claudia, Di Girolamo, Claudia, Pepe, Gerardo, De Bardi, Marco, Borsellino, Giovanna, Helmer-Citterich, Manuela, Barilà, Daniela

“…Glioblastoma is a severe brain tumor characterized by an extremely poor survival rate of patients. Glioblastoma cancer cells escape to standard therapeutic…”
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mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells by Colella, Barbara, Colardo, Mayra, Iannone, Gianna, Contadini, Claudia, Saiz-Ladera, Cristina, Fuoco, Claudia, Barilà, Daniela, Velasco, Guillermo, Segatto, Marco, Di Bartolomeo, Sabrina

“…Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on the surface of numerous cell types, which activates several…”
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Cross-Modal Interactions Between Auditory Attention and Oculomotor Control by Zhao, Sijia, Contadini-Wright, Claudia, Chait, Maria

“…Microsaccades are small, involuntary eye movements that occur during fixation. Their role is debated with recent hypotheses proposing a contribution to…”
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Pupil Dilation and Microsaccades Provide Complementary Insights into the Dynamics of Arousal and Instantaneous Attention during Effortful Listening by Contadini-Wright, Claudia, Magami, Kaho, Mehta, Nishchay, Chait, Maria

“…Listening in noisy environments requires effort- the active engagement of attention and other cognitive abilities- as well as increased arousal. The ability to…”
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Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene by Santoliquido, Benedetta M, Frenquelli, Michela, Contadini, Claudia, Bestetti, Stefano, Gaviraghi, Marco, Barbieri, Elisa, De Antoni, Anna, Albarello, Luca, Amabile, Angelo, Gardini, Alessandro, Lombardo, Angelo, Doglioni, Claudio, Provero, Paolo, Soddu, Silvia, Cittaro, Davide, Tonon, Giovanni

“…The oncogenic role of common fragile sites (CFS), focal and pervasive gaps in the cancer genome arising from replicative stress, remains controversial…”
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