Search Results - "Constantinof, Andrea"

Programming of stress pathways: A transgenerational perspective by Constantinof, Andrea, Moisiadis, Vasilis G., Matthews, Stephen G.

“…•Glucocorticoid exposure in uteroaffects development through epigenetic mechanisms.•Excess glucocorticoid exposure in utero creates heritable changes in…”
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Antenatal Glucocorticoid Exposure Results in Sex-Specific and Transgenerational Changes in Prefrontal Cortex Gene Transcription that Relate to Behavioural Outcomes by Constantinof, Andrea, Moisiadis, Vasilis G., Kostaki, Alisa, Szyf, Moshe, Matthews, Stephen G.

“…Synthetic glucocorticoids (sGC) are administered to women at risk for pre-term delivery to reduce respiratory distress syndrome in the newborn. The prefrontal…”
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Chorioamnionitis Induces a Specific Signature of Placental ABC Transporters Associated with an Increase of miR-331-5p in the Human Preterm Placenta by do Imperio, Guinever Eustaquio, Bloise, Enrrico, Javam, Mohsen, Lye, Phetcharawan, Constantinof, Andrea, Dunk, Caroline, dos Reis, Fernando Marcos, Lye, Stephen James, Gibb, William, Ortiga-Carvalho, Tania M., Matthews, Stephen Giles

“…Background/Aims: The ATP-binding cassette (ABC) transporters mediate drug biodisposition and immunological responses in the placental barrier. In vitro…”
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Prenatal maternal glucocorticoid exposure modifies sperm miRNA profiles across multiple generations in the guinea‐pig by Hamada, Hirotaka, Casciaro, Christopher, Moisiadis, Vasilis G., Constantinof, Andrea, Kostaki, Alisa, Matthews, Stephen G.

“…Maternal stress and glucocorticoid exposure during pregnancy have multigenerational effects on neuroendocrine function and behaviours in offspring…”
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Prenatal Glucocorticoid Exposure Modifies Endocrine Function and Behaviour for 3 Generations Following Maternal and Paternal Transmission by Moisiadis, Vasilis G., Constantinof, Andrea, Kostaki, Alisa, Szyf, Moshe, Matthews, Stephen G.

“…Fetal exposure to high levels of glucocorticoids programs long-term changes in the physiologic stress response and behaviours. However, it is not known whether…”
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Prenatal Glucocorticoid Exposure Results in Changes in Gene Transcription and DNA Methylation in the Female Juvenile Guinea Pig Hippocampus Across Three Generations by Constantinof, Andrea, Boureau, Lisa, Moisiadis, Vasilis G., Kostaki, Alisa, Szyf, Moshe, Matthews, Stephen G.

“…Synthetic glucocorticoids (sGC) are administered to women at risk for pre-term delivery, to mature the fetal lung and decrease neonatal morbidity. sGC also…”
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Gestational age‐dependent gene expression profiling of ATP‐binding cassette transporters in the healthy human placenta by Imperio, Guinever E., Javam, Mohsen, Lye, Phetcharawan, Constantinof, Andrea, Dunk, Caroline E., Reis, Fernando M., Lye, Stephen J., Gibb, William, Matthews, Stephen G., Ortiga‐Carvalho, Tania Maria, Bloise, Enrrico

“…The ATP‐binding cassette (ABC) transporters control placental transfer of several nutrients, steroids, immunological factors, chemicals, and drugs at the…”
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Cocaine exposure prior to pregnancy alters the psychomotor response to cocaine and transcriptional regulation of the dopamine D1 receptor in adult male offspring by Sasaki, Aya, Constantinof, Andrea, Pan, Pauline, Kupferschmidt, Dave A., McGowan, Patrick O., Erb, Suzanne

“…•Cocaine prior to pregnancy enhanced psychomotor sensitivity to cocaine in adult male offspring.•This enhanced sensitivity to cocaine in the offspring was…”
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Transgenerational Effects of Antenatal Synthetic Glucocorticoid Exposure on Transcription and Methylation in the Developing Brain by Constantinof, Andrea

“…The early environment has long term influences on future health that are heritable over multiple generations via maternal and paternal lineages. Antenatal…”
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Reply to Commentary Letter by Dr. Melvin Khee Shing Leow by Constantinof, Andrea, Moisiadis, Vasilis G., Matthews, Stephen G.

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The DNA methylation landscape of enhancers in the guinea pig hippocampus by Boureau, Lisa, Constantinof, Andrea, Moisiadis, Vasilis G, Matthews, Stephen G, Szyf, Moshe

“…To determine the state of methylation of DNA molecules in the guinea pig hippocampus that are associated with either poised or active enhancers. We used…”
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Electrochemical Oxidation of Benzothiazole Dyes for Monitoring Amyloid Formation Related to the Alzheimer’s Disease by Veloso, Anthony Joseph, Hung, Vinci Wing Sze, Sindhu, Guneet, Constantinof, Andrea, Kerman, Kagan

“…Alzheimer’s disease (AD) is associated with the formation and deposition of amyloid fibrils. A better understanding of the oligomeric intermediates on the…”
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Electrochemical detection of interaction between Thioflavin T and acetylcholinesterase by Dounin, Vladimir, Constantinof, Andrea, Schulze, Holger, Bachmann, Till T, Kerman, Kagan

“…The electrochemical oxidation of the benzothiazole dye Thioflavin T (ThT) was found to be modulated by its interaction with electric eel acetylcholinesterase…”
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Application of Epigenetic Techniques to Study Lactase Expression by Constantinof, Andrea

“…DNA methylation is a highly studied epigenetic modification. Numerous techniques have been developed to investigate DNA methylation and its role in gene…”
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