Search Results - "Consalvo, A"

Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment by Ciavardelli, D, Rossi, C, Barcaroli, D, Volpe, S, Consalvo, A, Zucchelli, M, De Cola, A, Scavo, E, Carollo, R, D'Agostino, D, Forlì, F, D'Aguanno, S, Todaro, M, Stassi, G, Di Ilio, C, De Laurenzi, V, Urbani, A

“…A number of studies suggest that cancer stem cells are essential for tumour growth, and failure to target these cells can result in tumour relapse. As this…”
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Expression profiling of extramedullary acute myeloid leukemia suggests involvement of epithelial–mesenchymal transition pathways by Ottone, T., Silvestrini, G., Piazza, R., Travaglini, S., Gurnari, C., Marchesi, F., Nardozza, A. M., Fabiani, E., Attardi, E., Guarnera, L., Divona, M., Ricci, P., Irno Consalvo, M. A., Ienzi, S., Arcese, R., Biagi, A., Fiori, L., Novello, M., Mauriello, A., Venditti, A., Anemona, L., Voso, M. T.

“…Extramedullary (EM) colonization is a rare complication of acute myeloid leukemia (AML), occurring in about 10% of patients, but the processes underlying…”
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Clinical conundrums in management of sepsis in the elderly by Sehgal, Vishal, Bajwa, Sukhminder Jit Singh, Consalvo, John A., Bajaj, Anurag

“…In 2012, surviving sepsis campaign came out with updated international guidelines for management of severe sepsis and septic shock. Paradoxically, there are no…”
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Management of diabetes in the elderly with canagliflozin: A newer hypoglycemic drug on the horizon by Sehgal, Vishal, Bajwa, Sukhminder Jit Singh, Sehgal, Rinku, Consalvo, John A

“…Canagliflozin is the first available oral inhibitor of sodium/glucose cotransporter 2 (SGLT2) in the market. At the outset it sounds excellent for the use in…”
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Production of Recombinant Salmon Calcitonin by In Vitro Amidation of an Escherichia coli Produced Precursor Peptide by Ray, Martha V. L, Duyne, Paul Van, Bertelsent, Arthur H, Jackson-Matthews, Dianne E, Sturmer, Amy M, Merkler, David J, Consalvo, Angelo P, Young, Stanley D, Gilligan, James P, Shields, Paul P

“…Salmon calcitonin (sCT) is a 32 amino acid peptide hormone that requires C-terminal amidation for full biological activity. We have produced salmon calcitonin…”
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A fluorometric assay for peptidyl alpha-amidation activity using high-performance liquid chromatography by Jones, B N, Tamburini, P P, Consalvo, A P, Young, S D, Lovato, S J, Gilligan, J P, Jeng, A Y, Wennogle, L P

“…A rapid and sensitive method for the determination of peptidyl alpha-amidation activity has been developed and is based on reverse-phase high-performance…”
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18O isotopic 13C NMR shift as proof that bifunctional peptidylglycine α-amidating enzyme is a monooxygenase by MERKLER, D. J, RAVIRAJ KULATHILA, CONSALVO, A. P, YOUNG, S. D, ASH, D. E

“…The biosynthesis of C-terminal alpha-amidated peptides from their corresponding C-terminal glycine-extended precursors is catalyzed by peptidylglycine…”
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Structure-activity relationships for glycine-extended peptides and the alpha-amidating enzyme derived from medullary thyroid CA-77 cells by Tamburini, P P, Jones, B N, Consalvo, A P, Young, S D, Lovato, S J, Gilligan, J P, Wennogle, L P, Erion, M, Jeng, A Y

“…A peptidyl alpha-amidating enzyme has been partially purified from conditioned medium derived from cultured medullary thyroid CA-77 cells. The interactions of…”
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A rapid fluorometric assay for N-terminal glutaminyl cyclase activity using high-performance liquid chromatography by Consalvo, A P, Young, S D, Jones, B N, Tamburini, P P

“…A rapid, sensitive method for the quantification of glutaminyl cyclase activity has been developed. The assay involves enzymatic conversion of the model…”
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Peptide substrate specificity of the alpha-amidating enzyme isolated from rat medullary thyroid CA-77 cells by Tamburini, P P, Young, S D, Jones, B N, Palmesino, R A, Consalvo, A P

“…The kinetic parameters were obtained for enzymatic alpha-amidation of peptides of the form N-dansyl-(Gly)4-X-Gly-OH, in which the amino acid at position X was…”
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Management of diabetes mellitus in the elderly with canagliflozin: A newer hypoglycemic drug on the horizon by Sehgal, Vishal, Bajwa, Sukhminder Jit Singh, Sehgal, Rinku, Consalvo, John A

“…Canagliflozin is the first available oral inhibitor of sodium/glucose cotransporter 2 (SGLT2) in the market. At the outset it sounds excellent for the use in…”
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Bifunctional peptidylglcine alpha-amidating enzyme requires two copper atoms for maximum activity by Kulathila, R, Consalvo, A P, Fitzpatrick, P F, Freeman, J C, Snyder, L M, Villafranca, J J, Merkler, D J

“…The conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides occurs in two distinct reactions, both of which are catalyzed by…”
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super(18)O isotopic super(13)C NMR shift as proof that bifunctional peptidylglycine alpha -amidating enzyme is a monooxygenase by Merkler, D J, Kulathila, R, Consalvo, A P, Young, S D, Ash, DE

“…The biosynthesis of C-terminal alpha -amidated peptides from their corresponding C-terminal glycine-extended precursors is catalyzed by peptidylglycine alpha…”
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Production of salmon calcitonin by direct expression of a glycine-extended precursor in Escherichia coli by Ray, Martha V.L., Meenan, Christopher P., Consalvo, Angelo P., Smith, Carrie A., Parton, Douglas P., Sturmer, Amy M., Shields, Paul P., Mehta, Nozer M.

“…The export of heterologous products into the conditioned medium of an Escherichia coli culture offers the advantages of a higher product yield, an increased…”
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Rapid fluorimetric assay for the detection of the peptidyl alpha-amidating enzyme intermediate using high-performance liquid chromatography by Consalvo, A P, Young, S D, Merkler, D J

“…Peptidylglycine alpha-amidating enzyme catalyzes the conversion of glycine-extended peptides to their corresponding amidated peptides via a stable…”
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