Search Results - "Conroy, Pauline C"

C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis by Conroy, Pauline C., Saladino, Chiara, Dantas, Tiago J., Lalor, Pierce, Dockery, Peter, Morrison, Ciaran G.

“…Cilia are found on most human cells and exist as motile cilia or non-motile primary cilia. Primary cilia play sensory roles in transducing various…”
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Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair by Dantas, Tiago J, Daly, Owen M, Conroy, Pauline C, Tomas, Martin, Wang, Yifan, Lalor, Pierce, Dockery, Peter, Ferrando-May, Elisa, Morrison, Ciaran G

“…Centrosomes, the principal microtubule-organising centres in animal cells, contain centrins, small, conserved calcium-binding proteins unique to eukaryotes…”
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Centriole separation in DNA damage-induced centrosome amplification by Saladino, Chiara, Bourke, Emer, Conroy, Pauline C, Morrison, Ciaran G

“…Altered centrosome numbers are seen in tumor cells in response to DNA damaging treatments and are hypothesised to contribute to cancer development. The…”
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Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells by Flach, Johanna, Bakker, Sietske T., Mohrin, Mary, Conroy, Pauline C., Pietras, Eric M., Reynaud, Damien, Alvarez, Silvia, Diolaiti, Morgan E., Ugarte, Fernando, Forsberg, E. Camilla, Le Beau, Michelle M., Stohr, Bradley A., Méndez, Juan, Morrison, Ciaran G., Passegué, Emmanuelle

“…Haematopoietic stem cell (HSC) function is known to degrade with age; here, replication stress is shown to be a potent driver of the functional decline of HSCs…”
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Centriole Separation in DNA Damage-Induced Centrosome Amplification: Special issue focused on centrosome structure and function under normal and pathological conditions by SALADINO, Chiara, BOURKE, Emer, CONROY, Pauline C, MORRISON, Ciaran G

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