Search Results - "Conrey, Peyton E."

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19 by Vella, Laura A, Giles, Josephine R, Baxter, Amy E, Oldridge, Derek A, Diorio, Caroline, Kuri-Cervantes, Leticia, Alanio, Cécile, Pampena, M Betina, Wu, Jennifer E, Chen, Zeyu, Huang, Yinghui Jane, Anderson, Elizabeth M, Gouma, Sigrid, McNerney, Kevin O, Chase, Julie, Burudpakdee, Chakkapong, Lee, Jessica H, Apostolidis, Sokratis A, Huang, Alexander C, Mathew, Divij, Kuthuru, Oliva, Goodwin, Eileen C, Weirick, Madison E, Bolton, Marcus J, Arevalo, Claudia P, Ramos, Andre, Jasen, C J, Conrey, Peyton E, Sayed, Samir, Giannini, Heather M, D'Andrea, Kurt, Meyer, Nuala J, Behrens, Edward M, Bassiri, Hamid, Hensley, Scott E, Henrickson, Sarah E, Teachey, David T, Betts, Michael R, Wherry, E John

“…Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder disease than in adults. A subset of children,…”
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IgA deficiency destabilizes homeostasis toward intestinal microbes and increases systemic immune dysregulation by Conrey, Peyton E, Denu, Lidiya, O'Boyle, Kaitlin C, Rozich, Isaiah, Green, Jamal, Maslanka, Jeffrey, Lubin, Jean-Bernard, Duranova, Tereza, Haltzman, Brittany L, Gianchetti, Lauren, Oldridge, Derek A, De Luna, Nina, Vella, Laura A, Allman, David, Spergel, Jonathan M, Tanes, Ceylan, Bittinger, Kyle, Henrickson, Sarah E, Silverman, Michael A

“…The ability of most patients with selective immunoglobulin A (IgA) deficiency (SIgAD) to remain apparently healthy has been a persistent clinical conundrum…”
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IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation by Silverman, Michael A, Conrey, Peyton E., Denu, Lidiya, O’Boyle, Kaitlin C, Tanes, Ceylan, Green, Jamal, Bittinger, Kyle, Allman, David, Lubin, Jean-Bernard, Duranova, Tereza, Oldridge, Derek, Henrickson, Sarah

“…Abstract Mammals produce large quantities of mucosal and systemic antibodies that maintain the intestinal barrier, shape the intestinal microbiome and promote…”
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Primary Immune Regulatory Disorders (PIRDs) That Amplify mTOR Signaling Share a T Cell Exhaustion-like Process by Conrey, Peyton E, Campos, Jose, Mauracher, Andrea, Sayed, Samir, Walter, Jolan E., Su, Helen, Barmettler, Sara, Leiding, Jennifer W, Cooper, Megan, MacFarland, Suzanne P, Ruffner, Melanie A, Farmer, Jocelyn R, Rao, V. Koneti, Henrickson, Sarah E

“…Background: Primary Immune Regulatory Disorders (PIRDs) are a complex and challenging-to-treat subset of Inborn Errors of Immunity (IEI), which are…”
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Dysregulation of CD8+ T cell function in the setting of altered cytokine signaling due to inborn errors of immunity by Campos Duran, Jose S., Conrey, Peyton E., Sayed, Samir, Di, Chao, Gonzalez, Elena N., Romberg, Neil D., Bergerson, Jenna R.E., Holland, Steve M., Freeman, Alexandra F., Su, Helen C., Leiding, Jennifer W., Forbes, Lisa R., Vogel, Tiphanie P., Henrickson, Sarah E.

“…Abstract A key outcome of chronic antigenic stimulation in the setting of sustained inflammation is the development of CD8+ T cell exhaustion. However, the…”
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Amplified STAT3 signaling alters expression of CD39 in STAT3 gain-of-function (STAT3 GOF) and in healthy donor CD8 +T cells by Campos Duran, Jose S., Sayed, Samir, Conrey, Peyton E., Hay, Ceire A., Dalalo, Megan C., Schmitt, Erica G., Mauracher, Andrea A., Romberg, Neil D., Holland, Steven M., Freeman, Alexandra F., Bergerson, Jenna R.E., Su, Helen C., Leiding, Jennifer W., Forbes, Lisa R., Cooper, Megan A., Vogel, Tiphanie P., Henrickson, Sarah E.

“…Abstract It is still unknown whether primary immune regulatory disorders (PIRD) due to genetic variants that amplify T cell receptor and/or inflammatory…”
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The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants by Materna, Marie, Delmonte, Ottavia M, Bosticardo, Marita, Momenilandi, Mana, Conrey, Peyton E, Charmeteau-De Muylder, Bénédicte, Bravetti, Clotilde, Bellworthy, Rebecca, Cederholm, Axel, Staels, Frederik, Ganoza, Christian A, Darko, Samuel, Sayed, Samir, Le Floc'h, Corentin, Ogishi, Masato, Rinchai, Darawan, Guenoun, Andrea, Bolze, Alexandre, Khan, Taushif, Gervais, Adrian, Krüger, Renate, Völler, Mirjam, Palterer, Boaz, Sadeghi-Shabestari, Mahnaz, Langlois de Septenville, Anne, Schramm, Chaim A, Shah, Sanjana, Tello-Cajiao, John J, Pala, Francesca, Amini, Kayla, Campos, Jose S, Lima, Noemia Santana, Eriksson, Daniel, Lévy, Romain, Seeleuthner, Yoann, Jyonouchi, Soma, Ata, Manar, Al Ali, Fatima, Stittrich, Anna, Deswarte, Caroline, Pereira, Anaïs, Mégret, Jérôme, Le Voyer, Tom, Bastard, Paul, Berteloot, Laureline, Dussiot, Michaël, Vladikine, Natasha, Cardenas, Paula P, Jouanguy, Emmanuelle, Alqahtani, Mashael, Hasan, Amal, Thanaraj, Thangavel Alphonse, Rosain, Jérémie, Al Qureshah, Fahd, Sabato, Vito, Alyanakian, Marie Alexandra, Leruez-Ville, Marianne, Rozenberg, Flore, Haddad, Elie, Regueiro, Jose R, Toribio, Maria L, Kelsen, Judith R, Salehi, Mansoor, Nasiri, Shahram, Torabizadeh, Mehdi, Rokni-Zadeh, Hassan, Changi-Ashtiani, Majid, Vatandoost, Nasimeh, Moravej, Hossein, Akrami, Seyed Mohammad, Mazloomrezaei, Mohsen, Cobat, Aurélie, Meyts, Isabelle, Toyofuku, Etsushi, Nishimura, Madoka, Moriya, Kunihiko, Mizukami, Tomoyuki, Imai, Kohsuke, Abel, Laurent, Malissen, Bernard, Al-Mulla, Fahd, Alkuraya, Fowzan Sami, Parvaneh, Nima, von Bernuth, Horst, Beetz, Christian, Davi, Frédéric, Douek, Daniel C, Cheynier, Rémi, Langlais, David, Landegren, Nils, Marr, Nico, Morio, Tomohiro, Shahrooei, Mohammad, Schrijvers, Rik, Henrickson, Sarah E, Luche, Hervé, Notarangelo, Luigi D, Casanova, Jean-Laurent, Béziat, Vivien

“…We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts…”
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