Search Results - "Conradie, Andelé M"

Distinct polymorphisms in a single herpesvirus gene are capable of enhancing virulence and mediating vaccinal resistance by Conradie, Andelé M, Bertzbach, Luca D, Trimpert, Jakob, Patria, Joseph N, Murata, Shiro, Parcells, Mark S, Kaufer, Benedikt B

“…Modified-live herpesvirus vaccines are widely used in humans and animals, but field strains can emerge that have a higher virulence and break vaccinal…”
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Mechanism of Virus Attenuation by Codon Pair Deoptimization by Groenke, Nicole, Trimpert, Jakob, Merz, Sophie, Conradie, Andelé M., Wyler, Emanuel, Zhang, Hongwei, Hazapis, Orsalia-Georgia, Rausch, Sebastian, Landthaler, Markus, Osterrieder, Nikolaus, Kunec, Dusan

“…Codon pair deoptimization is an efficient virus attenuation strategy, but the mechanism that leads to attenuation is unknown. The strategy involves synthetic…”
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Latest Insights into Marek's Disease Virus Pathogenesis and Tumorigenesis by Bertzbach, Luca D, Conradie, Andelé M, You, Yu, Kaufer, Benedikt B

“…Marek's disease virus (MDV) infects chickens and causes one of the most frequent cancers in animals. Over 100 years of research on this oncogenic…”
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The Marek's Disease Virus Unique Gene MDV082 Is Dispensable for Virus Replication but Contributes to a Rapid Disease Onset by You, Yu, Conradie, Andelé M, Kheimar, Ahmed, Bertzbach, Luca D, Kaufer, Benedikt B

“…Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus of chickens that causes lymphomas in various organs. Most MDV genes are conserved among…”
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Combinatorial Drug Treatments Reveal Promising Anticytomegaloviral Profiles for Clinically Relevant Pharmaceutical Kinase Inhibitors (PKIs) by Wild, Markus, Kicuntod, Jintawee, Seyler, Lisa, Wangen, Christina, Bertzbach, Luca D, Conradie, Andelé M, Kaufer, Benedikt B, Wagner, Sabrina, Michel, Detlef, Eickhoff, Jan, Tsogoeva, Svetlana B, Bäuerle, Tobias, Hahn, Friedrich, Marschall, Manfred

“…Human cytomegalovirus (HCMV) is a human pathogenic herpesvirus associated with a variety of clinical symptoms. Current antiviral therapy is not always…”
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Artesunate derivative TF27 inhibits replication and pathogenesis of an oncogenic avian alphaherpesvirus by Bertzbach, Luca D., Conradie, Andelé M., Hahn, Friedrich, Wild, Markus, Marschall, Manfred, Kaufer, Benedikt B.

“…Nucleoside analogues have been the cornerstone of clinical treatment of herpesvirus infections since the 1970s. However, severe side effects and emergence of…”
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The Diverse Major Histocompatibility Complex Haplotypes of a Common Commercial Chicken Line and Their Effect on Marek's Disease Virus Pathogenesis and Tumorigenesis by Bertzbach, Luca D, Tregaskes, Clive A, Martin, Rebecca J, Deumer, Undine-Sophie, Huynh, Lan, Kheimar, Ahmed M, Conradie, Andelé M, Trimpert, Jakob, Kaufman, Jim, Kaufer, Benedikt B

“…The major histocompatibility complex (MHC) is crucial for appropriate immune responses against invading pathogens. Chickens possess a single…”
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Establishment of different plasmid only-based reverse genetics systems for the recovery of African horse sickness virus by Conradie, Andelé M, Stassen, Liesel, Huismans, Henk, Potgieter, Christiaan A, Theron, Jacques

“…Abstract In an effort to simplify and expand the utility of African horse sickness virus (AHSV) reverse genetics, different plasmid-based reverse genetics…”
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A Common Live-Attenuated Avian Herpesvirus Vaccine Expresses a Very Potent Oncogene by Conradie, Andelé M, Bertzbach, Luca D, Bhandari, Nirajan, Parcells, Mark, Kaufer, Benedikt B

“…Vaccines play a crucial role in the protection of animals and humans from deadly pathogens. The first vaccine that also protected against cancer was developed…”
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Viral and cellular telomerase RNAs possess host-specific anti-apoptotic functions by Kheimar, Ahmed, Trapp-Fragnet, Laetitia, Conradie, Andelé M., Bertzbach, Luca D., You, Yu, Sabsabi, Mohammad A., Kaufer, Benedikt B.

“…ABSTRACT Human telomerase RNA (hTR) is overexpressed in many cancers and protects T cells from apoptosis in a telomerase-independent manner. The most prevalent…”
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Telomeric repeats in the commercial SB-1 vaccine facilitate viral integration and contribute to vaccine efficacy by You, Yu, Kheimar, Ahmed M., Vychodil, Tereza, Kossak, Lisa, Sabsabi, Mohammad A., Conradie, Andelé M., Reddy, Sanjay M., Bertzbach, Luca D., Kaufer, Benedikt B.

“…Marek’s disease virus (MDV) integrates its genome into the telomeres of host chromosomes and causes fatal lymphomas in chickens. This integration is…”
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A Genetically Engineered Commercial Chicken Line Is Resistant to Highly Pathogenic Avian Leukosis Virus Subgroup J by Kheimar, Ahmed, Klinger, Romina, Bertzbach, Luca D, Sid, Hicham, Yu, You, Conradie, Andelé M, Schade, Benjamin, Böhm, Brigitte, Preisinger, Rudolf, Nair, Venugopal, Kaufer, Benedikt B, Schusser, Benjamin

“…Viral diseases remain a major concern for animal health and global food production in modern agriculture. In chickens, avian leukosis virus subgroup J (ALV-J)…”
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Correction for You et al., “The Marek’s Disease Virus Unique Gene MDV082 Is Dispensable for Virus Replication but Contributes to a Rapid Disease Onset” by You, Yu, Conradie, Andelé M., Kheimar, Ahmed, Bertzbach, Luca D., Kaufer, Benedikt B.

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Marek's Disease Virus Requires Both Copies of the Inverted Repeat Regions for Efficient In Vivo Replication and Pathogenesis by Vychodil, Tereza, Conradie, Andelé M, Trimpert, Jakob, Aswad, Amr, Bertzbach, Luca D, Kaufer, Benedikt B

“…Marek's disease virus (MDV) is an oncogenic alphaherpesvirus of chickens. The MDV genome consists of two unique regions that are both flanked by inverted…”
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In vivo imaging reveals novel replication sites of a highly oncogenic avian herpesvirus in chickens by Lantier, Isabelle, Mallet, Corentin, Souci, Laurent, Larcher, Thibaut, Conradie, Andele M, Courvoisier, Katia, Trapp, Sascha, Pasdeloup, David, Kaufer, Benedikt B, Denesvre, Caroline

“…In vivo bioluminescence imaging facilitates the non-invasive visualization of biological processes in living animals. This system has been used to track virus…”
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African horse sickness virus infects BSR cells through macropinocytosis by Vermaak, Elaine, Conradie, Andelé M, Maree, Francois F, Theron, Jacques

“…Abstract Cellular pathways involved in cell entry by African horse sickness virus (AHSV), a member of the Orbivirus genus within the Reoviridae family, have…”
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