Search Results - "Connors, C"

Teaching the blind to find their way by playing video games by Merabet, Lotfi B, Connors, Erin C, Halko, Mark A, Sánchez, Jaime

“…Computer based video games are receiving great interest as a means to learn and acquire new skills. As a novel approach to teaching navigation skills in the…”
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Treatment with a retinoic acid-inducible gene I (RIG-I) agonist as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors: results from two phase 1 studies by Moreno, V., Calvo, E., Middleton, M. R., Barlesi, F., Gaudy-Marqueste, C., Italiano, A., Romano, E., Marabelle, A., Chartash, E., Dobrenkov, K., Zhou, H., Connors, E. C., Zhang, Y., Wermke, M.

“…Background We evaluated MK-4621, an oligonucleotide that binds and activates retinoic acid–inducible gene I (RIG-I), as monotherapy (NCT03065023) and in…”
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The IGF-1/Akt Pathway Is Neuroprotective in Huntington's Disease and Involves Huntingtin Phosphorylation by Akt by Humbert, Sandrine, Bryson, Elzbieta A., Cordelières, Fabrice P., Connors, Nathan C., Datta, Sandeep R., Finkbeiner, Steven, Greenberg, Michael E., Saudou, Frédéric

“…In the search for neuroprotective factors in Huntington's disease, we found that insulin growth factor 1 via activation of the serine/threonine kinase Akt/PKB…”
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Recommendations from a Canadian Delphi consensus study on best practice for optimal referral and appropriate management of severe asthma by Godbout, K, Bhutani, M, Connors, L, Chan, C K N, Connors, C, Dorscheid, D, Dyck, G, Foran, V, Kaplan, A G, Reynolds, J, Waserman, S

“…In Canada, severe asthma affects an estimated 5-10% of people with asthma and is associated with frequent exacerbations, poor symptom control and significant…”
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Potassium channel Kir4.1 macromolecular complex in retinal glial cells by Connors, Nathan C., Kofuji, Paulo

“…A major role for Müller cells in the retina is to buffer changes in the extracellular K+ concentration ([K+]o) resulting from light‐evoked neuronal activity…”
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The potassium channel Kir4.1 associates with the dystrophin-glycoprotein complex via alpha-syntrophin in glia by Connors, Nathan C, Adams, Marvin E, Froehner, Stanley C, Kofuji, Paulo

“…One of the major physiological roles of potassium channels in glial cells is to promote "potassium spatial buffering" in the central nervous system, a process…”
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Health service changes to address diabetes in pregnancy in a complex setting: perspectives of health professionals by Kirkham, R, Boyle, J A, Whitbread, C, Dowden, M, Connors, C, Corpus, S, McCarthy, L, Oats, J, McIntyre, H D, Moore, E, O'Dea, K, Brown, A, Maple-Brown, L

“…Australian Aboriginal and Torres Strait Islander women have high rates of gestational and pre-existing type 2 diabetes in pregnancy. The Northern Territory…”
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Comorbidity Burden and Adverse Outcomes After Transcatheter Aortic Valve Replacement by Feldman, Daniel R, Romashko, Mikhail D, Koethe, Benjamin, Patel, Sonika, Rastegar, Hassan, Zhan, Yong, Resor, Charles D, Connors, Annie C, Kimmelstiel, Carey, Allen, David, Weintraub, Andrew R, Wessler, Benjamin S

“…Background Transcatheter aortic valve replacement (TAVR) has become the preferred treatment for symptomatic patients with aortic stenosis and elevated…”
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Diabetes care in remote Australia: the antenatal, postpartum and inter-pregnancy period by Kirkham, R, Trap-Jensen, N, Boyle, J A, Barzi, F, Barr, E L M, Whitbread, C, Van Dokkum, P, Kirkwood, M, Connors, C, Moore, E, Zimmet, P, Corpus, S, Hanley, A J, O'Dea, K, Oats, J, McIntyre, H D, Brown, A, Shaw, J E, Maple-Brown, L

“…Aboriginal and Torres Strait Islander women experience high rates of diabetes in pregnancy (DIP), contributing to health risks for mother and infant, and the…”
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Preconception care for women with type 2 diabetes mellitus: A mixed-methods study of provider knowledge and practice by Klein, J, Boyle, J.A, Kirkham, R, Connors, C, Whitbread, C, Oats, J, Barzi, F, McIntyre, D, Lee, I, Luey, M, Shaw, J, Brown, A.D.H, Maple-Brown, L.J

“…Highlights • Practitioners reported enthusiasm for preconception care and knowledge of guidelines. • Practitioners aimed to offer opportunistic preconception…”
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Irreducible Ankle Fracture Dislocation Due to Tibialis Posterior Tendon Interposition: A Case Report by Connors, James C., DPM, Coyer, Michael A., DPM, Hardy, Mark A., DPM, FACFAS

“…Abstract Traumatic ankle fractures and dislocations that fail closed reduction present a challenging set of circumstances that can potentially lead to…”
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Dystrophin Dp71 Is Critical for the Clustered Localization of Potassium Channels in Retinal Glial Cells by Connors, Nathan C, Kofuji, Paulo

“…The Müller cell is the principal glial cell of the vertebrate retina. The primary conductance in Müller cells is the inwardly rectifying potassium channel…”
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Comparing Outcomes after Transthoracic and Transhiatal Esophagectomy: A 5-Year Prospective Cohort of 17,395 Patients by Connors, Rafe C., MD, Reuben, Brian C., MD, Neumayer, Leigh A., MD, FACS, Bull, David A., MD, FACS

“…Background Debate continues over whether transhiatal esophagectomy (THE) offers decreased morbidity and mortality compared with transthoracic esophagectomy…”
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Social Desirability and Affective Polarization by Connors, Elizabeth C

“…Abstract Media coverage of affective polarization—partisans disliking and distrusting out-partisans while liking and trusting in-partisans—is abundant, both…”
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The Social Dimension of Political Values by Connors, Elizabeth C.

“…Worries about the instability of political attitudes and lack of ideological constraint among the public are often pacified by the assumption that individuals…”
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Health Education Advanced Leadership for Zimbabwe (Healz): Developing the Infrastructure to Support Curriculum Reform by Aagaard, Eva M, Connors, Susan C, Challender, Amelia, Gandari, Jonathan, Nathoo, Kusum, Borok, Margaret, Chidzonga, Midion, Barry, Michele, Campbell, Thomas, Hakim, James

“…An economic crisis in Zimbabwe from 1999-2009 resulted in a shortage of faculty at the University of Zimbabwe College of Health Sciences (UZCHS) and declining…”
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Effect of work-hour restriction on operative experience in cardiothoracic surgical residency training by Connors, Rafe C., MD, Doty, John R., MD, Bull, David A., MD, May, Heidi T, Fullerton, David A., MD, Robbins, Robert C., MD

“…Objective Resident work-hour regulations were instituted to improve patient care during resident training. Although initial data have not shown the intended…”
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Party Foul: The Effectiveness of Political Value Rhetoric is Constrained by Party Ownership by Connors, Elizabeth C.

“…Politicians use political value rhetoric to win elections or persuade constituents towards policy positions, but the effectiveness of this rhetoric is unclear…”
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Improvement of glucaric acid production in E. coli via dynamic control of metabolic fluxes by Reizman, Irene M. Brockman, Stenger, Andrew R., Reisch, Chris R., Gupta, Apoorv, Connors, Neal C., Prather, Kristala L.J.

“…D-glucaric acid can be used as a building block for biopolymers as well as in the formulation of detergents and corrosion inhibitors. A biosynthetic route for…”
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Birth outcomes in women with gestational diabetes managed by lifestyle modification alone: The PANDORA study by Cheng, E., Longmore, D.K., Barzi, F., Barr, E.L.M., Lee, I.L., Whitbread, C., Boyle, J.A., Oats, J., Connors, C., McIntyre, H.D., Kirkwood, M., Dempsey, K., Zhang, X., Thomas, S., Williams, D., Zimmet, P., Brown, A.D.H., Shaw, J.E., Maple-Brown, L.J.

“…To assess outcomes of women in the Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) cohort with gestational diabetes mellitus (GDM)…”
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