Search Results - "Connor, V"

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence by Belk, Julia A., Yao, Winnie, Ly, Nghi, Freitas, Katherine A., Chen, Yan-Ting, Shi, Quanming, Valencia, Alfredo M., Shifrut, Eric, Kale, Nupura, Yost, Kathryn E., Duffy, Connor V., Daniel, Bence, Hwee, Madeline A., Miao, Zhuang, Ashworth, Alan, Mackall, Crystal L., Marson, Alexander, Carnevale, Julia, Vardhana, Santosh A., Satpathy, Ansuman T.

“…T cell exhaustion limits antitumor immunity, but the molecular determinants of this process remain poorly understood. Using a chronic stimulation assay, we…”
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Coupling dinitrogen and hydrocarbons through aryl migration by McWilliams, Sean F., Broere, Daniël L. J., Halliday, Connor J. V., Bhutto, Samuel M., Mercado, Brandon Q., Holland, Patrick L.

“…The activation of abundant molecules such as hydrocarbons and atmospheric nitrogen (N 2 ) remains a challenge because these molecules are often inert. The…”
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Covalently-crosslinked mucin biopolymer hydrogels for sustained drug delivery by Duffy, Connor V., David, Laurent, Crouzier, Thomas

“…[Display omitted] The sustained delivery of both hydrophobic and hydrophilic drugs from hydrogels has remained a challenge requiring the design and scalable…”
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ecDNA hubs drive cooperative intermolecular oncogene expression by Hung, King L., Yost, Kathryn E., Xie, Liangqi, Shi, Quanming, Helmsauer, Konstantin, Luebeck, Jens, Schöpflin, Robert, Lange, Joshua T., Chamorro González, Rocío, Weiser, Natasha E., Chen, Celine, Valieva, Maria E., Wong, Ivy Tsz-Lo, Wu, Sihan, Dehkordi, Siavash R., Duffy, Connor V., Kraft, Katerina, Tang, Jun, Belk, Julia A., Rose, John C., Corces, M. Ryan, Granja, Jeffrey M., Li, Rui, Rajkumar, Utkrisht, Friedlein, Jordan, Bagchi, Anindya, Satpathy, Ansuman T., Tjian, Robert, Mundlos, Stefan, Bafna, Vineet, Henssen, Anton G., Mischel, Paul S., Liu, Zhe, Chang, Howard Y.

“…Extrachromosomal DNA (ecDNA) is prevalent in human cancers and mediates high expression of oncogenes through gene amplification and altered gene regulation 1 …”
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Mechanical, compositional and morphological characterisation of the human male urethra for the development of a biomimetic tissue engineered urethral scaffold by Cunnane, Eoghan M., Davis, Niall F., Cunnane, Connor V., Lorentz, Katherine L., Ryan, Alan J., Hess, Jochen, Weinbaum, Justin S., Walsh, Michael T., O'Brien, Fergal J., Vorp, David A.

“…This study addresses a crucial gap in the literature by characterising the relationship between urethral tissue mechanics, composition and gross structure. We…”
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A Review of the Hemodynamic Factors Believed to Contribute to Vascular Access Dysfunction by Cunnane, Connor V., Cunnane, Eoghan M., Walsh, Michael T.

“…A vascular access (VA) is used to facilitate hemodialysis in patients that suffer from end-stage renal disease. However, they suffer from high failure rates…”
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Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection by Biering, Scott B., Sarnik, Sylvia A., Wang, Eleanor, Zengel, James R., Leist, Sarah R., Schäfer, Alexandra, Sathyan, Varun, Hawkins, Padraig, Okuda, Kenichi, Tau, Cyrus, Jangid, Aditya R., Duffy, Connor V., Wei, Jin, Gilmore, Rodney C., Alfajaro, Mia Madel, Strine, Madison S., Nguyenla, Xammy, Van Dis, Erik, Catamura, Carmelle, Yamashiro, Livia H., Belk, Julia A., Begeman, Adam, Stark, Jessica C., Shon, D. Judy, Fox, Douglas M., Ezzatpour, Shahrzad, Huang, Emily, Olegario, Nico, Rustagi, Arjun, Volmer, Allison S., Livraghi-Butrico, Alessandra, Wehri, Eddie, Behringer, Richard R., Cheon, Dong-Joo, Schaletzky, Julia, Aguilar, Hector C., Puschnik, Andreas S., Button, Brian, Pinsky, Benjamin A., Blish, Catherine A., Baric, Ralph S., O’Neal, Wanda K., Bertozzi, Carolyn R., Wilen, Craig B., Boucher, Richard C., Carette, Jan E., Stanley, Sarah A., Harris, Eva, Konermann, Silvana, Hsu, Patrick D.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of symptoms in infected individuals, from mild respiratory illness to acute…”
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Instantaneous and Phosphine-Catalyzed Arene Binding and Reduction by U(III) Complexes by Arnold, Polly L, Halliday, Connor J. V, Puig-Urrea, Laura, Nichol, Gary S

“…Neutral arenes such as benzene have never been considered suitable ligands for electropositive actinide cations, yet we find that even simple UIII UX3…”
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Improved Protein Inference from Multiple Protease Bottom-Up Mass Spectrometry Data by Miller, Rachel M, Millikin, Robert J, Hoffmann, Connor V, Solntsev, Stefan K, Sheynkman, Gloria M, Shortreed, Michael R, Smith, Lloyd M

“…Peptides detected by tandem mass spectrometry (MS/MS) in bottom-up proteomics serve as proxies for the proteins expressed in the sample. Protein inference is a…”
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In vivo ureteroscopic intrarenal pressures and clinical outcomes: a multi‐institutional analysis of 120 consecutive patients by Croghan, Stefanie M., Cunnane, Eoghan M., O'Meara, Sorcha, Muheilan, Muheilan, Cunnane, Connor V., Patterson, Kenneth, Skolarikos, Andreas, Somani, Bhaskar, Jack, Gregory S., Forde, James C., O'Brien, Fergal J., Walsh, Michael T., Manecksha, Rustom P., McGuire, Barry B., Davis, Niall F.

“…ObjectivesTo evaluate the pressure range generated in the human renal collecting system during ureteroscopy (URS), in a large patient sample, and to…”
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Human in vivo baseline intrarenal pressure, peristaltic activity and response to ureteric stenting by Croghan, Stefanie M., Cunnane, Eoghan M., O’Meara, Sorcha, Cunnane, Connor V., Forde, James C., Manecksha, Rustom P., Walsh, Michael T., Breen, Kieran J., McGuire, Barry B., O’Brien, Fergal J., Davis, Niall F.

“…Objectives To assess human in vivo intrarenal pressure (IRP) and peristaltic activity at baseline and after ureteric stent placement, using a narrow calibre…”
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Mechanical and morphological characterisation of porcine urethras for the assessment of paediatric urinary catheter safety by Cunnane, Eoghan M., Cunnane, Connor V., Allardyce, Joanna M., Croghan, Stefanie M., Walsh, Michael T., Davis, Niall F., Flood, Hugh D., Mulvihill, John J.E.

“…Paediatric urinary catheters are often necessary in critical care settings or to address congenital anomalies affecting the urogenital system. Iatrogenic…”
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A Combined Experimental and Theoretical Investigation of Arene-Supported Actinide and Ytterbium Tetraphenolate Complexes by Lam, Francis Y. T, Wells, Jordann A. L, Ochiai, Tatsumi, Halliday, Connor J. V, McCabe, Karl N, Maron, Laurent, Arnold, Polly L

“…Modular tetraphenolate ligands tethered with a protective arene platform (para-phenyl or para-terphenyl) are used to support mononuclear An­(IV) (An = Th, U)…”
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The mechanisms and drivers of lithification in slag‐dominated artificial ground by MacDonald, John M., Brolly, Connor V., Slaymark, Charlotte, Spruženiece, Liene, Wilson, Claire, Hilderman, Robin

“…Unconsolidated artificial ground is an ever‐increasing feature on the Earth's surface but it poses various challenges such as pollutant release and ground…”
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Mechanical characteristics of the ureter and clinical implications by O’Meara, Sorcha, Cunnane, Eoghan M., Croghan, Stefanie M., Cunnane, Connor V., Walsh, Michael T., O’Brien, Fergal J., Davis, Niall F.

“…The ureteric wall is a complex multi-layered structure. The ureter shows variation in passive mechanical properties, histological morphology and insertion…”
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The presence of helical flow can suppress areas of disturbed shear in parameterised models of an arteriovenous fistula by Cunnane, Connor V., Cunnane, Eoghan M., Moran, Daniel T., Walsh, Michael T.

“…Areas of disturbed shear that develop following arteriovenous fistula (AVF) creation are believed to trigger the onset of intimal hyperplasia (IH), leading to…”
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A Prospective Multi-Institutional Evaluation of Iatrogenic Urethral Catheterization Injuries by Croghan, Stefanie M., Hayes, Leah, O'Connor, Eabhann M., Rochester, Mark, Finch, William, Carrie, Anne, Considine, Shane W., D'Arcy, Frank, Riogh, Aisling Nic an, Mahmalji, Wasim, Elhadi, Mohammed, Thursby, Helen, Pearce, Ian, Modgil, Vaibhav, Noweir, Hosam, MacCraith, Eoin, Madden, Aideen, Manecksha, Rustom, Browne, Eva, Giri, Subhasis K., Cunnane, Connor V., Mulvihill, John, Walsh, Michael T., Davis, Niall F., Flood, Hugh D.

“…To perform a multi-institutional investigation of incidence and outcomes of urethral trauma sustained during attempted catheterization. A prospective,…”
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Structure of the Fc fragment of the NIST reference antibody RM8671 by Gallagher, D. Travis, Galvin, Connor V., Karageorgos, Ioannis

“…As the link between antigen binding and immune activation, the antibody Fc region has received extensive structural study. In this report, the structure of the…”
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Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting by Wei, Jingyi, Lotfy, Peter, Faizi, Kian, Baungaard, Sara, Gibson, Emily, Wang, Eleanor, Slabodkin, Hannah, Kinnaman, Emily, Chandrasekaran, Sita, Kitano, Hugo, Durrant, Matthew G, Duffy, Connor V, Pawluk, April, Hsu, Patrick D, Konermann, Silvana

“…Effective and precise mammalian transcriptome engineering technologies are needed to accelerate biological discovery and RNA therapeutics. Despite the promise…”
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Influence of Herpes Simplex Virus 1 Latency-Associated Transcripts on the Establishment and Maintenance of Latency in the ROSA26R Reporter Mouse Model by NICOLL, M. P, PROENCA, J. T, CONNOR, V, EFSTATHIOU, S

“…OA  Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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