Search Results - "Connor, Michael K."

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest by Slingerland, Joyce M, Liang, Jiyong, Zubovitz, Judit, Petrocelli, Teresa, Kotchetkov, Rouslan, Connor, Michael K, Han, Kathy, Lee, Jin-Hwa, Ciarallo, Sandra, Catzavelos, Charles, Beniston, Richard, Franssen, Edmee

“…Mechanisms linking mitogenic and growth inhibitory cytokine signaling and the cell cycle have not been fully elucidated in either cancer or in normal cells…”
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Proliferative endocrine effects of adipose tissue from obese animals on MCF7 cells are ameliorated by resveratrol supplementation by Theriau, Christopher F, Sauvé, O'Llenecia S, Beaudoin, Marie-Soleil, Wright, David C, Connor, Michael K

“…Obesity is clearly associated with an increased risk of breast cancer in postmenopausal women. The purpose was to determine if obesity alters the adipocyte…”
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Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells by Freyssenet, Damien, Irrcher, Isabella, Connor, Michael K, Di Carlo, Martino, Hood, David A

“…Cytochrome c expression and mitochondrial biogenesis can be invoked by elevated intracellular Ca(2+) in muscle cells. To characterize the potential role of…”
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Voluntary physical activity abolishes the proliferative tumor growth microenvironment created by adipose tissue in animals fed a high fat diet by Theriau, Christopher F, Shpilberg, Yaniv, Riddell, Michael C, Connor, Michael K

“…The molecular mechanisms behind the obesity-breast cancer association may be regulated via adipokine secretion by white adipose tissue. Specifically,…”
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Synergistic activation of mitochondrial metabolism and the glutathione redox couple protects HepG2 hepatocarcinoma cells from palmitoylcarnitine-induced stress by Turnbull, Patrick C, Dehghani, Ali C, Theriau, Christopher F, Connor, Michael K, Perry, Christopher G R

“…Fatty acid stress can have divergent effects in various cancers. We explored how metabolic and redox flexibility in HepG2 hepatocarcinoma cells mediates…”
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Molecular Characterization of Ring Finger Protein 11 by Connor, Michael K, Azmi, Peter B, Subramaniam, Venkateswaran, Li, Hoaxia, Seth, Arun

“…Ring finger proteins serve many vital functions within the cell. We have identified RNF11, a novel 154-amino acid ring finger–containing protein, which is…”
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Muscle‐specific AMPK β1β2‐null mice display a myopathy due to loss of capillary density in nonpostural muscles by Thomas, Melissa M., Wang, David C., D'Souza, Donna M., Krause, Matthew P., Layne, Andrew S., Criswell, David S., O'Neill, Hayley M., Connor, Michael K., Anderson, Judy E., Kemp, Bruce E., Steinberg, Gregory R., Hawke, Thomas J.

“…ABSTRACT AMP‐activated protein kinase (AMPK) is a master regulator of metabolism. While Muscle‐specific AMPK β1β2 double‐knockout (β1β2M‐KO) mice display…”
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Voluntary physical activity counteracts the proliferative tumor growth microenvironment created by adipose tissue via high‐fat diet feeding in female rats by Theriau, Christopher F., Connor, Michael K.

“…The adipokine secretion profile created from adipose tissue may represent the molecular mechanism behind the obesity‐breast cancer association. Two adipokines,…”
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CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis by Connor, Michael K, Kotchetkov, Rouslan, Cariou, Sandrine, Resch, Ansgar, Lupetti, Rafaella, Beniston, Richard G, Melchior, Frauke, Hengst, Ludger, Slingerland, Joyce M

“…We show that p27 localization is cell cycle regulated and we suggest that active CRM1/RanGTP-mediated nuclear export of p27 may be linked to cytoplasmic p27…”
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The direct and indirect effects of corticosterone and primary adipose tissue on MCF7 breast cancer cell cycle progression by Shpilberg, Yaniv, Connor, Michael K, Riddell, Michael C

“…Breast cancer is the second leading cause of cancer-related mortality in women. Glucocorticoids (GCs) have the potential to directly affect breast cancer or…”
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Exercise effects on adipokines and the IGF axis in men with prostate cancer treated with androgen deprivation: A randomized study by Santa Mina, Daniel, Connor, Michael K, Alibhai, Shabbir M H, Toren, Paul, Guglietti, Crissa, Matthew, Andrew G, Trachtenberg, John, Ritvo, Paul

“…Androgen deprivation therapy (ADT) has significant deleterious effects on body composition that may be accompanied by unfavourable changes in adipokine levels…”
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A central role for the ring finger protein RNF11 in ubiquitin-mediated proteolysis via interactions with E2s and E3s by Connor, Michael K, Seth, Arun

“…The identification of novel tumor-associated genes represents an important area of cancer research. To that end, we have discovered a number of genes whose…”
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Contractile Activity-induced Transcriptional Activation of Cytochrome c Involves Sp1 and Is Proportional to Mitochondrial ATP Synthesis in C2C12 Muscle Cells by Connor, Michael K., Irrcher, Isabella, Hood, David A.

“…Contractile activity induces adaptations in the expression of genes encoding skeletal muscle mitochondrial proteins; however, the putative signals responsible…”
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Muscle‐specific AMPK β1β2‐null mice display a myopathy due to loss of capillary density in nonpostural muscles by Thomas, Melissa M., Wang, David C., D'Souza, Donna M., Krause, Matthew P., Layne, Andrew S., Criswell, David S., O'Neill, Hayley M., Connor, Michael K., Anderson, Judy E., Kemp, Bruce E., Steinberg, Gregory R., Hawke, Thomas J.

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Tom20-mediated mitochondrial protein import in muscle cells during differentiation by Grey, J Y, Connor, M K, Gordon, J W, Yano, M, Mori, M, Hood, D A

“…Mitochondrial biogenesis is accompanied by an increased expression of components of the protein import machinery, as well as increased import of proteins…”
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Cytochrome c transcriptional activation and mRNA stability during contractile activity in skeletal muscle by Freyssenet, D, Connor, M K, Takahashi, M, Hood, D A

“…We evaluated contractile activity-induced alterations in cytochrome c transcriptional activation and mRNA stability with unilateral chronic stimulation (10 Hz,…”
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Effect of contractile activity on protein turnover in skeletal muscle mitochondrial subfractions by Connor, Michael K, Bezborodova, Olga, Escobar, C. Patricia, Hood, David A

“…Departments of Biology and of Kinesiology and Health Science, York University, Toronto, Canada M3J 1P3 To determine the role of intramitochondrial protein…”
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CRM1/Ran-Mediated Nuclear Export of p27Kip1 Involves a Nuclear Export Signal and Links p27 Export and Proteolysis by Connor, Michael K., Kotchetkov, Rouslan, Cariou, Sandrine, Resch, Ansgar, Lupetti, Rafaella, Beniston, Richard G., Melchior, Frauke, Hengst, Ludger, Slingerland, Joyce M.

“…We show that p27 localization is cell cycle regulated and we suggest that active CRM1/RanGTP-mediated nuclear export of p27 may be linked to cytoplasmic p27…”
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Effect of microgravity on the expression of mitochondrial enzymes in rat cardiac and skeletal muscles by Connor, Michael K, Hood, David A

“…Departments of Biology and Kinesiology and Health Science, York University, Toronto, Ontario, Canada M3J 1P3 Connor, Michael K., and David A. Hood. Effect of…”
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A Survey of Patient Experience During Molecular Breast Imaging by Hruska, Carrie B, Gray, Lacey R, Jenkins, Sarah M, Block, Emily A, Hunt, Katie N, Conners, Amy Lynn, Zingula, Shannon N, O'Connor, Michael K, Rhodes, Deborah J

“…Molecular breast imaging (MBI) is one of several options available to patients seeking supplemental screening due to mammographically dense breasts. Patient…”
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