Search Results - "Connor, HE"

Pharmacological characterization of GSK1004723, a novel, long‐acting antagonist at histamine H 1 and H 3 receptors by Slack, RJ, Russell, LJ, Hall, DA, Luttmann, MA, Ford, AJ, Saunders, KA, Hodgson, ST, Connor, HE, Browning, C, Clark, KL

“…BACKGROUND AND PURPOSE Preclinical pharmacological characterization of GSK1004723, a novel, dual histamine H 1 and H 3 receptor antagonist. EXPERIMENTAL…”
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Recent developments in tachykinin NK1 receptor antagonists: prospects for the treatment of migraine headache by Beattie, D T, Connor, H E, Hagan, R M

“…The role of substance P and the influence of neurokinin 1 (NK1) receptor antagonists in the cranial circulation are described in the present review,…”
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Activation of sensory nerves in guinea-pig isolated basilar artery by nicotine: evidence for inhibition of trigeminal sensory neurotransmission by sumatriptan by O'Shaughnessy, C T, Connor, H E

“…Nicotine (100 microM), but not electrical field stimulation or potassium chloride (0.1-3 microM), caused capsaicin (1 microM)- and tetrodotoxin (1…”
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Lack of effect of sumatriptan and UK‐14,304 on capsaicin‐induced relaxation of guinea‐pig isolated basilar artery by O'Shaughnessy, C.T., Waldron, G.J., Connor, H.E.

“…1 The objectives of this study were to assess the effects of sensory neuropeptide antagonists and presynaptically acting receptor agonists on capsaicin‐induced…”
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Extracellular recordings of membrane potential from guinea-pig isolated trigeminal ganglion: lack of effect of sumatriptan by O'Shaughnessy, C T, Connor, H E, Feniuk, W

“…The aim of this study was to investigate the effect of the anti-migraine drug and selective 5-HT1 receptor agonist, sumatriptan, on membrane potential of…”
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Adenosine A(1) receptor agonists inhibit trigeminovascular nociceptive transmission by Goadsby, PJ, Hoskin, KL, Storer, RJ, Edvinsson, Lars, Connor, HE

“…There is a considerable literature to suggest that adenosine A(1) receptor agonists may have anti-nociceptive effects, and we sought to explore the role of…”
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Pharmacological characterization of GSK1004723, a novel, long‐acting antagonist at histamine H1 and H3 receptors by Slack, RJ, Russell, LJ, Hall, DA, Luttmann, MA, Ford, AJ, Saunders, KA, Hodgson, ST, Connor, HE, Browning, C, Clark, KL

“…BACKGROUND AND PURPOSE Preclinical pharmacological characterization of GSK1004723, a novel, dual histamine H1 and H3 receptor antagonist. EXPERIMENTAL APPROACH…”
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GR127935: a potent and selective 5-HT1D receptor antagonist by Skingle, M, Beattie, D T, Scopes, D I, Starkey, S J, Connor, H E, Feniuk, W, Tyers, M B

“…GR127935 is the most potent 5-HT1D receptor antagonist yet described, possessing nanomolar affinity at human 5-HT1D receptors. Sumatriptan-induced contractions…”
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Flora of New Zealand - Gramineae Supplement II: Pooideae (Poeae, Triticeae) by Connor, H. E.

“…Two vexing grasses, Festuca rubra and Elymus scaber, are interpreted as species naturalised from Europe and Australia, respectively. There is no evidence for…”
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Flora of New Zealand - Gramineae Supplement III: Panicoideae by Connor, H. E.

“…The identity of Rottboellia uniflora A.Cunn. collected in Northland in 1834 by R. Cunningham is resolved as Paspalum vaginatum Sw.; confusion with Zoysia sp…”
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Flora of New Zealand - Gramineae supplement IV: Agrostideae, and an addendum to supplement I: Danthonioideae by Connor, H. E.

“…New data affect the lectotypification of the agrostidoids Dichelachne crinita, Echinopogon ovatus, Lachnagrostis filiformis, and Trisetum antarcticum, all…”
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Building on the sumatriptan experience: the development of naratriptan by Connor, H E

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Regional endemism in New Zealand grasses by Connor, H. E.

“…Regional endemism is evident in 60 grass taxa among the 182 species and infraspecific taxa that comprise the New Zealand endemic grass flora. The pattern of…”
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Naratriptan: biological profile in animal models relevant to migraine by Connor, H E, Feniuk, W, Beattie, D T, North, P C, Oxford, A W, Saynor, D A, Humphrey, P P

“…The biological profile of naratriptan (N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethane-sulphonamide), a novel 5HT1B/1D receptor agonist, was…”
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Species novae graminum Novae-Zelandiae II. Chionochloa nivifera (Danthonieae:Danthonioideae) by Connor, H. E., Lloyd, K. M.

“…A new species of Chionochloa, C. nivifera, is described from the high alpine zone of eastern Fiordland mountains. A species found in areas of long snow lie, it…”
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Study of an adenosine A1 receptor agonist on trigeminally evoked dural blood vessel dilation in the anaesthetized rat by Honey, A C, Bland-Ward, P A, Connor, H E, Feniuk, W, Humphrey, P P A

“…The purpose of this study was to use intravital microscopy to determine the effect of a selective adenosine A1 receptor agonist, GR79236 (1, 3 and 10 microg/kg…”
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Species novae graminum Novae-Zelandiae III. Two diploid species of Rytidosperma (Danthonieae: Danthonioideae) by Molloy, B. P. J., Connor, H. E.

“…Two diploid species of Rytidosperma, R. horrens and R. telmaticum, are described from central South Island, the latter as a segregate from R. pumilum. The…”
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Trigeminal ganglion stimulation increases facial skin blood flow in the rat: a major role for calcitonin gene-related peptide by Escott, K. Jane, Beattie, David T., Connor, Helen E., Brain, Susan D.

“…Activation of the trigeminovascular system leads to neurogenic inflammation within the dura mater and cerebral vasodilation. These processes have been…”
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Breeding systems in New Zealand grasses XII. Cleistogamy in Festuca by Connor, H. E.

“…Cleistogamy in Festuca is of a very simple form with floral expression primarily in anther size; it is a very low frequency phenomenon that occurs almost…”
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4991W93, a potent blocker of neurogenic plasma protein extravasation, inhibits trigeminal neurons at 5-hydroxytryptamine (5-HT 1B/1D) agonist doses by Storer, R.James, Akerman, Simon, Connor, Helen E, Goadsby, Peter J

“…Triptans share the pharmacological profile of being 5-hydroxytryptamine (5-HT 1B/1D) agonists and having potent anti-migraine activity. The conformationally…”
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