Search Results - "Connolly, Gregory C."

Incidence and predictors of venous thromboembolism (VTE) among ambulatory high‐risk cancer patients undergoing chemotherapy in the United States by Khorana, Alok A., Dalal, Mehul, Lin, Jay, Connolly, Gregory C.

“…BACKGROUND: Recent studies suggest that thromboprophylaxis is beneficial in preventing venous thromboembolism (VTE) in cancer outpatients, but this is not…”
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Assessing Risk of Venous Thromboembolism in the Patient With Cancer by Khorana, Alok A, Connolly, Gregory C

“…Patients with cancer are increasingly at risk for venous thromboembolism (VTE). Rates of VTE, however, vary markedly among patients with cancer. This review…”
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Cancer-associated thrombosis by Connolly, Gregory C, Francis, Charles W

“…Cancer-associated thrombosis accounts for almost one-fifth of all cases of venous thromboembolism (VTE) and is a leading cause of death, morbidity, delays in…”
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Emerging risk stratification approaches to cancer-associated thrombosis: risk factors, biomarkers and a risk score by Connolly, Gregory C, Khorana, Alok A

“…Abstract Cancer patients are well-known to be at increased risk of venous thromboembolism (VTE). However, the risk varies widely between patients and over the…”
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Leukocytosis, thrombosis and early mortality in cancer patients initiating chemotherapy by Connolly, Gregory C, Khorana, Alok A, Kuderer, Nicole M, Culakova, Eva, Francis, Charles W, Lyman, Gary H

“…Abstract Background Leukocytosis has been associated with thrombosis and mortality in cancer patients. We explored the association of leukocytosis with venous…”
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Prevalence and Clinical Significance of Incidental and Clinically Suspected Venous Thromboembolism in Lung Cancer Patients by Connolly, Gregory C, Menapace, Laurel, Safadjou, Saman, Francis, Charles W, Khorana, Alok A

“…Micro-Abstract The clinical significance of incidental venous thromboembolism (VTE) in lung cancer patients is unknown. VTE events were characterized in 207…”
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Risk stratification for cancer-associated venous thromboembolism by Connolly, Gregory C., MD, Khorana, Alok A., MD

“…The risk of venous thromboembolism (VTE) is elevated in cancer, and thrombosis is the second leading cause of death in patients with malignancy. Many risk…”
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Diabetes mellitus impacts risk of macrovascular invasion in patients undergoing transplantation for hepatocellular carcinoma by Connolly, Gregory C, Safadjou, Saman, Kashyap, Randeep, Chen, Rui, Orloff, Mark S, Hezel, Aram F

“…Diabetes mellitus (DM) is identified as a negative prognostic indicator in hepatocellular carcinoma (HCC), though the basis for this is unknown. This is a…”
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Platelets and Cancer-Associated Thrombosis by Connolly, Gregory C, Phipps, Richard P, Francis, Charles W

“…Platelets have a newly appreciated and important role in many cancer-related processes, including tumor growth and metastases, angiogenesis, and promotion of a…”
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Inhibition of Mrp2- and Ycf1p-mediated transport by reducing agents: evidence for GSH transport on rat Mrp2 by Rebbeor, James F, Connolly, Gregory C, Ballatori, Nazzareno

“…Mammalian Mrp2 and its yeast orthologue, Ycf1p, mediate the ATP-dependent cellular export of a variety of organic anions. Ycf1p also appears to transport the…”
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Anticoagulation in cancer-associated thromboembolism with thrombocytopenia: a prospective, multicenter cohort study by Carney, Brian J., Wang, Tzu-Fei, Ren, Siyang, George, Gemlyn, Al Homssi, Amer, Gaddh, Manila, Connolly, Gregory C., Shah, Vinay I., Bogue, Thomas, Bartosic, Abigail, Neuberg, Donna, Baumann Kreuziger, Lisa, Zwicker, Jeffrey I.

“…Venous thromboembolism (VTE) with concurrent thrombocytopenia is frequently encountered in patients with cancer. Therapeutic anticoagulation in the setting of…”
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Health care costs associated with venous thromboembolism in selected high-risk ambulatory patients with solid tumors undergoing chemotherapy in the United States by Khorana, Alok A, Dalal, Mehul R, Lin, Jay, Connolly, Gregory C

“…This study examines venous thromboembolism (VTE)-associated resource utilization and real-world costs in ambulatory patients initiating chemotherapy for…”
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ATP-dependent transport of reduced glutathione on YCF1, the yeast orthologue of mammalian multidrug resistance associated proteins by Rebbeor, J.F. (University of Rochester School of Medicine, Rochester, NY.), Connolly, G.C, Dumont, M.E, Ballatori, N

“…The transport systems involved in the export of cellular reduced glutathione (GSH) have not been identified, although recent studies implicate a role for some…”
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Diabetes Mellitus Is Associated With the Presence of Metastatic Spread at Disease Presentation in Hepatocellular Carcinoma by Connolly, Gregory C., Safadjou, Saman, Chen, Rui, Nduaguba, Afamefuna, Dunne, Richard, Khorana, Alok A., Hezel, Aram F.

“…Purpose: Diabetes mellitus (DM) is identified as a negative prognostic indicator in hepatocellular carcinoma (HCC). Methods: A retrospective review of HCC…”
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Incidence, risk factors and consequences of portal vein and systemic thromboses in hepatocellular carcinoma by Connolly, Gregory C, Chen, Rui, Hyrien, Ollivier, Mantry, Parvez, Bozorgzadeh, Adel, Abt, Peter, Khorana, Alok A

“…Abstract Introduction Hemostatic activation may be important for tumor biology. Hepatocellular carcinoma (HCC) is commonly associated with portal vein…”
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A Primitive ATP Receptor from the Little Skate Raja erinacea by Dranoff, Jonathan A., O'Neill, Allison F., Franco, Ann Marie, Cai, Shi-Ying, Connolly, Gregory C., Ballatori, Nazzareno, Boyer, James L., Nathanson, Michael H.

“…P2Y ATP receptors are widely expressed in mammalian tissues and regulate a broad range of activities. Multiple subtypes of P2Y receptors have been identified…”
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A Proteomics-Based Approach To Identifying Mechanisms Of Cancer-Associated Thrombosis: Potential Role For Immunoglobulins by Khorana, Alok A., Connolly, Gregory C., Hagen, Fred, Willard, Belinda, Iyer, Renuka, McCrae, Keith R.

“…Venous thromboembolism (VTE) is highly prevalent in cancer and has serious consequences, but underlying mechanisms are incompletely understood. Proteomics is a…”
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Assessing Risk of Venous Thromboembolism in the Patient With Cancer: Cancer and Thrombosis by KHORANA, Alok A, CONNOLLY, Gregory C

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Pharmacologic Thromboprophylaxis Is Frequently Prescribed In Hospitalized Cancer Patients At Academic Medical Centers: A Prospective, Cross-Sectional, Multi-Center Study by Rojan, Adam A., Rehman, Nadia Q., Funches, Renee E., Campigotto, Federico, Webster, Jonathan, Connolly, Gregory C., Aggarwal, Anita, Mobarek, Dalia, Neuberg, Donna S., Wun, Ted, Rickles, Frederick, Streiff, Michael B., Khorana, Alok A., Zwicker, Jeffrey I.

“…Venous thromboembolism (VTE) is a frequent complication in hospitalized cancer patients and is associated with increased morbidity and mortality. Guidelines…”
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ATP-dependent GSH and glutathione S-conjugate transport in skate liver: role of an Mrp functional homologue by Rebbeor, J F, Connolly, G C, Henson, J H, Boyer, J L, Ballatori, N

“…Multidrug resistance-associated proteins 1 and 2 (Mrp1 and Mrp2) are thought to mediate low-affinity ATP-dependent transport of reduced glutathione (GSH), but…”
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