Search Results - "Connie J. Weaver"
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Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage–stellate cell interaction
Published in Laboratory investigation (01-04-2014)“…Pancreatic cancer occurs in the setting of a profound fibrotic microenvironment that often dwarfs the actual tumor. Although pancreatic fibrosis has been well…”
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Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer
Published in Cellular and molecular gastroenterology and hepatology (01-01-2018)“…Background & Aims Chronic inflammation is a predisposing condition for colorectal cancer. Many studies to date have focused on proinflammatory signaling…”
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Journal Article -
3
SMAD4 Suppresses Colitis-associated Carcinoma Through Inhibition of CCL20/CCR6-mediated Inflammation
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2022)“…We previously reported that colon epithelial cell silencing of Smad4 increased epithelial expression of inflammatory genes, including the chemokine c-c motif…”
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Journal Article -
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Abstract A16: Smad4 pathways modulate induction of the chemokine Ccl20 and repress inflammation-induced carcinogenesis in mouse colon
Published in Cancer research (Chicago, Ill.) (01-02-2017)“…Abstract Inflammation regulates many aspects of gut homeostasis but is also a key component of colon cancer progression. While TGFβ signaling is known to…”
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Journal Article -
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Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia
Published in Oncogene (13-02-2014)“…Pancreatic cancer remains as one of the most deadly cancers with few treatment options at late stages and little information about how it develops through…”
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Journal Article -
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Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated CancerSummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2018)“…Background & Aims: Chronic inflammation is a predisposing condition for colorectal cancer. Many studies to date have focused on proinflammatory signaling…”
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Journal Article -
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A national survey of psychological assessment practices with hearing-impaired students
Published 01-01-1990“…A nationwide survey of 524 (371 were returned) school psychologists was conducted to determine their preparation for, and practices used with hearing-impaired…”
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Dissertation