Search Results - "Conneely, O M"

Multifunctional roles of lactoferrin: a critical overview by Ward, P P, Paz, E, Conneely, O M

“…Lactoferrin (LF) is a member of the transferrin family that is expressed and secreted by glandular epithelial cells and is found in the secondary granules of…”
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Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities by Lydon, J P, DeMayo, F J, Funk, C R, Mani, S K, Hughes, A R, Montgomery, Jr, C A, Shyamala, G, Conneely, O M, O'Malley, B W

“…Although progesterone has been recognized as essential for the establishment and maintenance of pregnancy, this steroid hormone has been recently implicated to…”
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Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform by Mulac-Jericevic, Biserka, Mullinax, Robert A., DeMayo, Francesco J., Lydon, John P., Conneely, Orla M.

“…Progesterone regulates reproductive function through two intracellular receptors, progesterone receptor-A (PR-A) and progesterone receptor-B (PR-B), that arise…”
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Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia by Boudreaux, S P, Ramirez-Herrick, A M, Duren, R P, Conneely, O M

“…Acute myeloid leukemias (AMLs) are a heterogeneous group of diseases that are sustained by relatively rare leukemia-initiating cells (LICs) that exhibit…”
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Progesterone via Its Receptor Antagonizes the Pro-Inflammatory Activity of Estrogen in the Mouse Uterus by TIBBETTS, T. A, CONNEELY, O. M, O'MALLEY, B. W

“…Populations of macrophages and neutrophils in the uterus are under the control of the female sex steroids estrogen and progesterone (P 4 ). Their influx is…”
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p53 is a Potential Mediator of Pregnancy and Hormone-Induced Resistance to Mammary Carcinogenesis by Sivaraman, Lakshmi, Conneely, Orla M., Medina, Daniel, O'Malley, Bert W.

“…Full-term pregnancy early in reproductive life is protective against breast cancer in women. Pregnancy also provides protection in animals against…”
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Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury by LE, W.-D, CONNEELY, O. M, HE, Y, JANKOVIC, J, APPEL, S. H

“…Mutation in the Nurr1 gene, a member of the nuclear receptor superfamily, causes selective agenesis of dopaminergic neurons in the midbrain of null mice…”
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Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation by Sivaraman, L, Hilsenbeck, SG, Zhong, L, Gay, J, Conneely, OM, Medina, D, O'Malley, BW

“…An early single full-term pregnancy induces a long-lasting protective effect against mammary tumor development in humans and rodents. This protective effect…”
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Mutual and Intercompartmental Regulation of Estrogen Receptor and Progesterone Receptor Expression in the Mouse Uterus by TIBBETTS, T. A, MENDOZA-MENESES, M, O'MALLEY, B. W, CONNEELY, O. M

“…The epithelial and stromal compartments of the uterus undergo significant estrogen- and progesterone (P 4 )-induced changes during the estrous cycle. While in…”
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Modulation of the Ligand-Independent Activation of the Human Estrogen Receptor by Hormone and Antihormone by Smith, Carolyn L., Conneely, Orla M., O'Malley, Bert W.

“…It has been previously demonstrated that several members of the steroid receptor superfamily may be activated by the neurotransmitter dopamine in the apparent…”
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Regulation of epidermal Langerhans cell migration by lactoferrin by Cumberbatch, M., Dearman, R. J., Uribe‐luna, S., Headon, D. R., Ward, P. P., Conneely, O. M., Kimber, I.

“…Summary Lactoferrin (LF) is a member of the transferrin family of iron‐binding glycoproteins to which several anti‐inflammatory functions have been ascribed…”
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Selective Agenesis of Mesencephalic Dopaminergic Neurons in Nurr1-Deficient Mice by Le, Wei-dong, Conneely, Orla M., Zou, Linglong, He, Yi, Saucedo-Cardenas, Odila, Jankovic, Joseph, Mosier, Dennis R., Appel, Stanley H.

“…Nurr1, a member of the nuclear receptor superfamily of transcription factors, has been found to be essential for the development of ventral midbrain dopamine…”
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Identification of a new brain-specific transcription factor, NURR1 by Law, S W, Conneely, O M, DeMayo, F J, O'Malley, B W

“…We have identified and cloned a novel member of the nuclear receptor superfamily. The cDNA was isolated from a mouse brain cDNA library and encodes a protein…”
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Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats by SIVARAMAN, L, STEPHENS, L. C, MARKAVERICH, B. M, CLARK, J. A, KRNACIK, S, CONNEELY, O. M, O'MALLEY, B. W, MEDINA, D

“…One of the most consistent results in the epidemiology of human breast cancer is the inverse relationship of risk and early full-term parity. The goal of this…”
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Cooperative Interactions between the Amino- and Carboxyl-terminal Lobes Contribute to the Unique Iron-binding Stability of Lactoferrin by Ward, P P, Zhou, X, Conneely, O M

“…Lactoferrin is a member of the transferrin family of iron-binding proteins. Several functions have been ascribed to lactoferrin, including regulation of iron…”
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A System for Production of Commercial Quantities of Human Lactoferrin: A Broad Spectrum Natural Antibiotic by Ward, Pauline P, Piddington, Christopher S, Cunningham, Grainne A, Zhou, Xiaodong, Wyatt, Roger D, Conneely, Orla M

“…We previously reported the production of limited quantities of biologically active recombinant human lactoferrin in the filamentous fungus Aspergillus oryzae…”
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The Chicken Progesterone Receptor A and B Isoforms Are Products of an Alternate Translation Initiation Event by Conneely, O M, Kettelberger, D M, Tsai, M J, Schrader, W T, O'Malley, B W

“…The chicken progesterone receptor A and B proteins differ by an additional 128 amino acids located at the N terminus of the B protein. Using site-directed…”
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Orphan receptors: in search of a unifying hypothesis for activation by O'Malley, B W, Conneely, O M

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A reappraisal of progesterone action in the mammary gland by Lydon, J P, Sivaraman, L, Conneely, O M

“…The ovarian hormones estrogen and progesterone and their respective receptors are essential for maintenance of postnatal developmental plasticity of the…”
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Dopamine Activation of an Orphan of the Steroid Receptor Superfamily by Power, Ronan F., Lydon, John P., Conneely, Orla M., O'Malley, Bert W.

“…The chicken ovalbumin upstream promoter transcription factor (COUP-TF) is a member of the steroid receptor superfamily and participates in the regulation of…”
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