Search Results - "Connaughton, M"

Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies by McArdle, Maeve A, Finucane, Orla M, Connaughton, Ruth M, McMorrow, Aoibheann M, Roche, Helen M

“…Obesity and associated chronic inflammation initiate a state of insulin resistance (IR). The secretion of chemoattractants such as MCP-1 and MIF and of…”
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Spatial and Temporal Clustering of Anti-Glomerular Basement Membrane Disease by Canney, Mark, O'Hara, Paul V, McEvoy, Caitriona M, Medani, Samar, Connaughton, Dervla M, Abdalla, Ahad A, Doyle, Ross, Stack, Austin G, O'Seaghdha, Conall M, Clarkson, Michael R, Griffin, Matthew D, Holian, John, Dorman, Anthony M, Niland, Aileen, Keogan, Mary, Wallace, Eleanor M, Conlon, Niall P, Walsh, Cathal, Kelly, Alan, Little, Mark A

“…An environmental trigger has been proposed as an inciting factor in the development of anti-GBM disease. This multicenter, observational study sought to define…”
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Reclassification of Genetic Testing Results: A Case Report Demonstrating the Need for Structured Re-Evaluation of Genetic Findings by Schott, Clara, Colaiacovo, Samantha, Baker, Cadence, Weir, Matthew A, Connaughton, Dervla M

“…Alport Syndrome (AS) is a progressive genetic condition characterized by chronic kidney disease (CKD), hearing loss, and eye abnormalities. It is caused by…”
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Karyomegalic Interstitial Nephritis: Cancer Risk Following Transplantation by Murray, Susan L, Connaughton, Dervla M, Fennelly, Neil K, Kay, Elaine W, Dorman, Anthony, Doyle, Brendan, Conlon, Peter J

“…A brother and sister presented individually in their forties with progressive renal failure, bronchiectasis and mild derangements of their liver function…”
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Tacrolimus trough-level variability predicts long-term allograft survival following kidney transplantation by O’Regan, John A., Canney, Mark, Connaughton, Dervla M., O’Kelly, Patrick, Williams, Yvonne, Collier, Geraldine, deFreitas, Declan G., O’Seaghdha, Conall M., Conlon, Peter J.

“…Aims The purpose of this study is to investigate tacrolimus trough-level variability from 3 to 12 months following transplantation and its association with…”
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Weighted Gene Co‐Expression Network Analysis Identifies Gender Specific Modules and Hub Genes Related to Metabolism and Inflammation in Response to an Acute Lipid Challenge by Fatima, Attia, Connaughton, Ruth M., Weiser, Anna, Murphy, Aoife M., O'Grada, Colm, Ryan, Miriam, Brennan, Lorraine, O'Gaora, Peadar, Roche, Helen M.

“…Scope Inflammation is characteristic of diet‐related diseases including obesity and type 2 diabetes (T2D). However, biomarkers of inflammation that reflect the…”
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An Exome Sequencing Study of 10 Families with IgA Nephropathy by Stapleton, Caragh P, Kennedy, Claire, Fennelly, Neil K, Murray, Susan L, Connaughton, Dervla M, Dorman, Anthony M, Doyle, Brendan, Cavalleri, Gianpiero L, Conlon, Peter J

“…Immunoglobulin A nephropathy (IgAN) is a heterogeneous disorder with a strong genetic component. The advent of whole exome sequencing (WES) has accelerated the…”
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COL4A1 mutations as a potential novel cause of autosomal dominant CAKUT in humans by Kitzler, Thomas M., Schneider, Ronen, Kohl, Stefan, Kolvenbach, Caroline M., Connaughton, Dervla M., Dai, Rufeng, Mann, Nina, Nakayama, Makiko, Majmundar, Amar J., Wu, Chen-Han W., Kari, Jameela A., El Desoky, Sherif M., Senguttuvan, Prabha, Bogdanovic, Radovan, Stajic, Natasa, Valivullah, Zaheer, Lek, Monkol, Mane, Shrikant, Lifton, Richard P., Tasic, Velibor, Shril, Shirlee, Hildebrandt, Friedhelm

“…Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease (~ 45%) that manifests before 30 years of age…”
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Utility of Genomic Testing after Renal Biopsy by Murray, Susan L, Dorman, Anthony, Benson, Katherine A, Connaughton, Dervla M, Stapleton, Caragh P, Fennelly, Neil K, Kennedy, Claire, McDonnell, Ciara A, Kidd, Kendrah, Cormican, Sarah M, Ryan, Louise A, Lavin, Peter, Little, Mark A, Bleyer, Anthony J, Doyle, Brendan, Cavalleri, Gianpiero L, Hildebrandt, Friedhelm, Conlon, Peter J

“…Renal biopsy is the mainstay of renal pathological diagnosis. Despite sophisticated diagnostic techniques, it is not always possible to make a precise…”
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Personalized medicine in chronic kidney disease by detection of monogenic mutations by Connaughton, Dervla M, Hildebrandt, Friedhelm

“…Abstract A large fraction of early-onset chronic kidney disease (CKD) is known to be monogenic in origin. To date, ∼450 monogenic (synonymous with single-gene…”
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Autosomal dominant tubulointerstitial kidney disease (ADTKD) in Ireland by Cormican, S., Connaughton, D. M., Kennedy, C., Murray, S., Živná, M., Kmoch, S., Fennelly, N. K., O'Kelly, P., Benson, K. A., Conlon, E. T., Cavalleri, G., Foley, C., Doyle, B., Dorman, A., Little, M. A., Lavin, P., Kidd, K., Bleyer, A. J., Conlon, P. J.

“…Introduction: Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a rare genetic cause of renal impairment resulting from mutations in the MUC1,…”
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Non-adherence to statin therapy: a major challenge for preventive cardiology by Bates, T R, Connaughton, V M, Watts, G F

“…Hypercholesterolemia is a major risk factor for atherosclerosis and cardiovascular disease, the leading cause of death worldwide. In the last twenty years,…”
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Effects of fish size and temperature on weakfish disturbance calls: implications for the mechanism of sound generation by Connaughton, M A, Taylor, M H, Fine, M L

“…To categorize variation in disturbance calls of the weakfish Cynoscion regalis and to understand their generation, we recorded sounds produced by…”
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Disease mechanisms of monogenic congenital anomalies of the kidney and urinary tract American Journal of Medical Genetics Part C by Connaughton, Dervla M., Hildebrandt, Friedhelm

“…Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) is a developmental disorder of the kidney and/or genito‐urinary tract that results in end stage…”
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Weakfish sonic muscle: influence of size, temperature and season by Connaughton, M A, Fine, M L, Taylor, M H

“…The influence of temperature, size and season on the sounds produced by the sonic muscles of the weakfish Cynoscion regalis are categorized and used to…”
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Disease mechanisms of monogenic congenital anomalies of the kidney and urinary tract by Connaughton, Dervla M., Hildebrandt, Friedhelm

“…Abstract Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) is a developmental disorder of the kidney and/or genito‐urinary tract that results in end…”
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Genotypic analysis of a large cohort of patients with suspected atypical hemolytic uremic syndrome by Connaughton, Dervla M., Bhai, Pratibha, Isenring, Paul, Mahdi, Mohammed, Sadikovic, Bekim, Schenkel, Laila C.

“…Atypical hemolytic uremic syndrome (aHUS) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. Complement and…”
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Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome by Cooke, Aoife A., Connaughton, Ruth M., Lyons, Claire L., McMorrow, Aoibheann M., Roche, Helen M.

“…The metabolic syndrome is a group of obesity associated metabolic conditions that result in increased risk of cardiovascular disease and type 2 diabetes…”
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Teaching NeuroImage: Extensive Brainstem and Striatal Involvement in Neuropsychiatric Systemic Lupus Erythematosus by Branch, Anna, Nuaaman, Mais M, Appleton, C Thomas, Connaughton, Dervla M, Basmaji, John, Chan, Tommy L H, Budhram, Adrian

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Proteomic analysis identifies ZMYM2 as endogenous binding partner of TBX18 protein in 293 and A549 cells by Lüdtke, Timo H-W, Kleppa, Marc-Jens, Rivera-Reyes, Reginaldo, Qasrawi, Fairouz, Connaughton, Dervla M, Shril, Shirlee, Hildebrandt, Friedhelm, Kispert, Andreas

“…The TBX18 transcription factor regulates patterning and differentiation programs in the primordia of many organs yet the molecular complexes in which TBX18…”
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